ID   W2JWS4_PHYPR            Unreviewed;      1236 AA.
AC   W2JWS4;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   27-MAR-2024, entry version 49.
DE   RecName: Full=Helicase ATP-binding domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=L917_21736 {ECO:0000313|EMBL:ETL77323.1};
OS   Phytophthora parasitica (Potato buckeye rot agent).
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Phytophthora.
OX   NCBI_TaxID=4792 {ECO:0000313|EMBL:ETL77323.1};
RN   [1] {ECO:0000313|EMBL:ETL77323.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CHvinca01 {ECO:0000313|EMBL:ETL77323.1};
RG   The Broad Institute Genomics Platform;
RA   Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA   Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA   Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA   Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA   Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA   Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA   Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Phytophthora parasitica CHvinca01.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KI683795; ETL77323.1; -; Genomic_DNA.
DR   AlphaFoldDB; W2JWS4; -.
DR   EnsemblProtists; ETL77323; ETL77323; L917_21736.
DR   VEuPathDB; FungiDB:PPTG_23120; -.
DR   VEuPathDB; FungiDB:PPTG_23121; -.
DR   Proteomes; UP000054423; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004518; F:nuclease activity; IEA:InterPro.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   CDD; cd17917; DEXHc_RHA-like; 1.
DR   CDD; cd18791; SF2_C_RHA; 1.
DR   Gene3D; 1.20.120.1080; -; 1.
DR   Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR007502; Helicase-assoc_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR029060; PIN-like_dom_sf.
DR   InterPro; IPR006086; XPG-I_dom.
DR   PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR   PANTHER; PTHR18934:SF234; ATP-DEPENDENT RNA HELICASE DHX40-RELATED; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF00867; XPG_I; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00847; HA2; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF88723; PIN domain-like; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          579..756
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          821..992
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
FT   REGION          509..560
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        517..543
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1236 AA;  138848 MW;  C8D09DA99E782A61 CRC64;
     MTLLQINGRF PFAPEKLRGV LKKHGIKVKT ATQEADDELG NLGRNGKAFA VLAEESDFLA
     MSGVRYIPFR ELSFYQYSQN LEQMRIRVRV FSSEMVAASL GLAVDQLVDL ALLCGNDFTP
     LEDNEFHMAT MLNFPMYGCN PILSQIEAQK KEFLRALFEI YRFYGHAAAF LNKFPMRIEP
     NLPPNKLELY KKMIDSYSFP LMAIDILETK GHKLNQRFDA LASVSGLKDK SLDELQAPVR
     HLSYLVLDTP VVKEETVRGC VEVHVVPLES LDPLISVPIQ SRSGKAVGRT FRSLVFVFLY
     GDSSGRTRRD RTCLKNRSLP DDKLLELLLL TSLISFTVDS SDPKSTDLEL TVFDERLLSM
     EIYAAVGGYL ETLKQLHHLR LLLGSKLPPN SGCSTYFSGE VFLKVCHTLM QSTRSSSTAG
     KSTKSASGLS CRAVESAISK FAEISDRKRF WSHYTNIRGA MQRMKELVAL PSGVARANVA
     SKSAATAALE NTMRSNGYIS VDGFDLRPPD ATPPLPLSSP SHLQTSVNAR SVRGLMTSKP
     TERTSTDDAV ESEPEPSTSV SLKGMMQTLP VFDHREEILK NVAINQLTII QGETGCGKST
     SVPQFFYNAW ARAKASFERP VNIYVTQPRR IAAIELTNTV ARMREGNAFD EVGQVGQVVG
     YRIGQKHVTS SKTKITYVTT GYMVERIIHD PEALTKITHL VLDEVHERSM DVDLLLLLLK
     LKFKNHPQVR VVIMSATMDA KLLIHYLANA LAARLVNRKP LCVGSKLYPV EDIYLDKLSD
     HFPGLSQRGQ QDLVLMKDQF KRLSKPQHMT NSKLARKSIM NIHDNQLKLI KEMVRCLIRE
     QTQQIESQSQ CILIFLPGIE VSTNLLHSEI ELGDQREAFK LLGVKSTKIV LSTNIAENSV
     TIPDVTHVIN CAVEKQIELS SVKKLHAEVL KANWCSKDSS IQRSGRAGRV MPGKAFHLFT
     KAFHGSCMAQ YTTPELLRKP LDRVILQFTG RLSEFKVPSS LLRGALDAPD LSHIDNAYRL
     LASFDAIDSE DEKDSRLTRF GSFVCHLPLS LQLCRLLMTG VYTVQDNTDQ VESCPLLLHT
     VILVSILSTP DLFIMLSFYH IRSAQTYLKE MKKNLQAKLK LDGGMWSEPL SIWLFYMETM
     SDQQINIKSN LRGIFHKFAI SSRRYQTLNY LISDLCQRLI SLSQTPEFSQ LIYAKGREVL
     SKLETYASTQ RVDKKLLKFA RDTVSGKRDE CVVFGS
//