ID W2K0K2_PHYPR Unreviewed; 1066 AA.
AC W2K0K2;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=ATP-dependent RNA helicase DOB1 {ECO:0008006|Google:ProtNLM};
GN ORFNames=L917_20539 {ECO:0000313|EMBL:ETL78696.1};
OS Phytophthora parasitica (Potato buckeye rot agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=4792 {ECO:0000313|EMBL:ETL78696.1};
RN [1] {ECO:0000313|EMBL:ETL78696.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHvinca01 {ECO:0000313|EMBL:ETL78696.1};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Phytophthora parasitica CHvinca01.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KI683216; ETL78696.1; -; Genomic_DNA.
DR AlphaFoldDB; W2K0K2; -.
DR EnsemblProtists; ETL78696; ETL78696; L917_20539.
DR VEuPathDB; FungiDB:PPTG_06148; -.
DR Proteomes; UP000054423; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR GO; GO:0006401; P:RNA catabolic process; IEA:InterPro.
DR CDD; cd18024; DEXHc_Mtr4-like; 1.
DR CDD; cd18795; SF2_C_Ski2; 1.
DR Gene3D; 1.10.3380.30; -; 1.
DR Gene3D; 1.20.1500.20; -; 1.
DR Gene3D; 2.40.30.300; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR048392; MTR4-like_stalk.
DR InterPro; IPR025696; MTR4_beta-barrel.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016438; SKI2-like.
DR InterPro; IPR012961; Ski2/MTR4_C.
DR PANTHER; PTHR12131; ATP-DEPENDENT RNA AND DNA HELICASE; 1.
DR PANTHER; PTHR12131:SF7; EXOSOME RNA HELICASE MTR4; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF08148; DSHCT; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF21408; MTR4-like_stalk; 1.
DR Pfam; PF13234; MTR4_beta-barrel; 1.
DR PIRSF; PIRSF005198; Antiviral_helicase_SKI2; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM01142; DSHCT; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242}.
FT DOMAIN 137..293
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 374..607
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..87
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 599..626
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 16..36
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 47..62
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1066 AA; 120019 MW; B7EACF20377A3216 CRC64;
MDEDLDLFGA FDDSSATLTA EEQAAASSTS TKRKEAPAAS PNDDKVSSPP AKKQQNEGRL
ASTNLKVVEG KRIDATPVDS NDKHSANVVS TGTQQKNLIS FSVYPPDYEA KPTAGAAAKN
PAKTYPFTLD PFQQQAVDYI ESGESVLVSA HTSAGKTAVA EYAIAKSLRD KQRVIYTSPI
KALSNQKYRD LEEEFGDVGL MTGDITINPS ATCLIMTTEI LRSMLYRGSE VMREVAWVIY
DEIHYMRDKE RGVVWEESII LLPHKVRFVF LSATIPNSKE FAGWICHIHH QPCHVVYTDY
RPTPLQHYIF PAGGNGLHLV VDEKGKFRED NFQKAIATLS ASADDAAQEL ASYGSNTKRR
KAQKSNPKKK IGTDVFRIVK LIMERQYDPV IIFSFSKREC EAYALLMSKL DFNTEEEKQS
VDQLFKNAMD SLSDDDRALP QVDSILPLLR RGIGIHHGGL LPILKEVIEI LFGEGLLKCL
FATETFSMGL NMPAKTVVFT NCRKYDGKDF RWITAGEYIQ MSGRAGRRSL DARGIVIQML
SEQMEPQVAK GILYGQADPL FSTFHLGYNM LLNLMRVEDA DPEYMIKQSF HQFQNEQAAP
VLEEALERAK EEKDQIVIKN EEEVAQYYYL SRSLVRLKEE FLAIRNKPDY VVRFLNGGRL
VKLYCPDSDD GTTRPKWDWG VIVNFTTKNA SDSTSATPDT VVHVLLNCMT NNGNTKANDA
TNGSTVSELP TPAPENMMGL STSANYEMKI CPVPLEMLDL ISSLRVYIPK DLRTLESRQA
VGKSVKEVLR RFPQGVPLLD PREDMDIQDE QFLRVIEKTV DAEKKLKSSA FHNAADKEAR
FALYNLKMES EAKMRELERK IKESKSLVLR DDLRRRRRVL RRLEFVDKEG VIQRKGRTAC
EVSTTDELLV TEMIFNGQFN DLSVNDTVAL LSCLINTEKK KETDKPPQAD SLEIPVRQLR
ETAQRIAKVM QDAKITIDVD EYAGAFNTSL VDVVIAWCQG AKFSQICKMS DAFEGTIIRC
LRRLEELLRQ LTLAAHSIGD VELEKKFDEG GKKLKRDIVF AASLYL
//
