ID   W2K181_PHYPR            Unreviewed;       997 AA.
AC   W2K181;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   27-MAR-2024, entry version 45.
DE   RecName: Full=FYVE-type domain-containing protein {ECO:0000259|PROSITE:PS50178};
GN   ORFNames=L917_20338 {ECO:0000313|EMBL:ETL78931.1};
OS   Phytophthora parasitica (Potato buckeye rot agent).
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Phytophthora.
OX   NCBI_TaxID=4792 {ECO:0000313|EMBL:ETL78931.1};
RN   [1] {ECO:0000313|EMBL:ETL78931.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CHvinca01 {ECO:0000313|EMBL:ETL78931.1};
RG   The Broad Institute Genomics Platform;
RA   Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA   Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA   Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA   Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA   Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA   Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA   Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Phytophthora parasitica CHvinca01.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; KI683157; ETL78931.1; -; Genomic_DNA.
DR   AlphaFoldDB; W2K181; -.
DR   EnsemblProtists; ETL78931; ETL78931; L917_20338.
DR   VEuPathDB; FungiDB:PPTG_18454; -.
DR   Proteomes; UP000054423; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd00065; FYVE_like_SF; 1.
DR   Gene3D; 3.30.530.20; -; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR013702; FIST_domain_N.
DR   InterPro; IPR023393; START-like_dom_sf.
DR   InterPro; IPR000306; Znf_FYVE.
DR   InterPro; IPR017455; Znf_FYVE-rel.
DR   InterPro; IPR011011; Znf_FYVE_PHD.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR13510; FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED; 1.
DR   PANTHER; PTHR13510:SF44; RABENOSYN-5; 1.
DR   Pfam; PF08495; FIST; 1.
DR   Pfam; PF01363; FYVE; 1.
DR   SMART; SM00897; FIST; 1.
DR   SMART; SM00064; FYVE; 1.
DR   SUPFAM; SSF55961; Bet v1-like; 1.
DR   SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR   PROSITE; PS50178; ZF_FYVE; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00091}.
FT   DOMAIN          413..473
FT                   /note="FYVE-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50178"
FT   REGION          1..113
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          238..258
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          606..627
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        28..56
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        57..84
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        85..113
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   997 AA;  107777 MW;  C091F761B85EA8BE CRC64;
     MDRFRLDLDG VDQDGVDTVE PMRPSSFDMT FSLGSYPSAQ GLSRDSDEQQ TSNQDDNDVT
     DSRKLPGRGE KGRLHVDELM ESSRSQKFDG SSLASSGHKR NTTASSPASS SMHKDVANIA
     LRLEEKAHEA IDVANLCGKV SWKLSKRTQD VHVYRPATLP SEEDSSTKLY FRVSCEVKAH
     LGTIMEYLTP SNSRSYYDIE SQVFPGLLHA AVIKRMELPE RAPASMANSG QTLLFPSGAS
     ATTTASGSHD DTSSVDEDSS DSFPHLQVKW HASRFAGRFV KPVDFFFVEY ANIEAMADGR
     KRGYGYIRSV ESFKGDELAI RLAGEDVAIP PSVAKCKRAV INKGVYVVSP SGDASGTYEV
     TCMMVIDFQK QFASSVGAKI IHNFTERLIG IRELLFNTLF RPIAVLPKNQ WKPARSNKCA
     ICMCSFSIVK SKHHCRSCGE AVCGQCSRKW TLQPGAQPET QARLCTSCSL QARSYLMPNG
     DPSRSPAGAS SRFSSVINDF SVSQLAGSRS AVPRMANVYK CDVQVASTVS HDPDTFAAAT
     SAFAKLVSAL GDQNPHFMLV SYSHHHNGAA VYEALARAAP DTLFMGGTSS GGVYVGATAS
     ALGLNKSGGN SSNNSRHRGN TGSQGPTVGL WGIYDPEGSY AILNADLDRE SPRDAARRCL
     TDGMKMLAME PEESPDFVWT VMGGGEDTYD VDDQRDGEEE QITRAVNEIV DCSYSVVGGS
     SSRHTASSRG HATQLCSEGG NVGCVTKHGA CFAICCPSVE VAHALFTCYD ATDKSFVVTK
     ASGRDLFALD HKPALEAINE ATHGMLAEMT QRPEKFNLES NLLPAYYPVA RERRGAVPRG
     LKRNTSRYQM LQPETSARDL SLHLGAEVRL GERLHMMSLS PRGVASKARR GLRDAIRVSV
     PTMDLQDVIG CFLSVGMSYD RVLQGDLNAV ADATGSAFPQ GASLLSVSHG QQGVMTGGNE
     AVHANSMLTA LIVTNRKKAQ KLNPLRPLNI RVATTTA
//