ID W2KQD7_PHYPR Unreviewed; 2093 AA.
AC W2KQD7;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=Dynein heavy chain {ECO:0008006|Google:ProtNLM};
GN ORFNames=L917_13417 {ECO:0000313|EMBL:ETL87373.1};
OS Phytophthora parasitica (Potato buckeye rot agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=4792 {ECO:0000313|EMBL:ETL87373.1};
RN [1] {ECO:0000313|EMBL:ETL87373.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHvinca01 {ECO:0000313|EMBL:ETL87373.1};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Phytophthora parasitica CHvinca01.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KI681095; ETL87373.1; -; Genomic_DNA.
DR EnsemblProtists; ETL87373; ETL87373; L917_13417.
DR VEuPathDB; FungiDB:PPTG_23535; -.
DR Proteomes; UP000054423; Unassembled WGS sequence.
DR GO; GO:0030286; C:dynein complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0045505; F:dynein intermediate chain binding; IEA:InterPro.
DR GO; GO:0051959; F:dynein light intermediate chain binding; IEA:InterPro.
DR GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 1.20.58.1120; -; 1.
DR Gene3D; 1.20.140.100; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.20.180.20; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR035699; AAA_6.
DR InterPro; IPR026983; DHC_fam.
DR InterPro; IPR042222; Dynein_2_N.
DR InterPro; IPR013602; Dynein_heavy_linker.
DR InterPro; IPR042228; Dynein_linker_3.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10676:SF396; DYNEIN AXONEMAL HEAVY CHAIN 1; 1.
DR PANTHER; PTHR10676; DYNEIN HEAVY CHAIN FAMILY PROTEIN; 1.
DR Pfam; PF12774; AAA_6; 1.
DR Pfam; PF08393; DHC_N2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
FT DOMAIN 1129..1571
FT /note="Dynein heavy chain linker"
FT /evidence="ECO:0000259|Pfam:PF08393"
FT DOMAIN 1721..1850
FT /note="Dynein heavy chain hydrolytic ATP-binding dynein
FT motor region"
FT /evidence="ECO:0000259|Pfam:PF12774"
FT REGION 316..379
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 322..341
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 363..379
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2093 AA; 234757 MW; 227DCADD02426B54 CRC64;
MDSVNNEVVR ESTIFATPSP RGYSKRGISS DARVTDSGAI PSGILPPVNP RDATSILRSP
TQLKSTFSPK TPQSLMMAVP MTMNECWLVW KFLCDWVKTQ LAMEVPASIP GFGTFYLRVQ
ALGIRITLFE PDKQFLNKFC LQVDSEMPDP ALVATLSSTV SNSDALASTE SISRAPSVVG
LGDVFAFSFV EMAACCGNAA DSKRAQEWLS AIVNKLGNAM SQCGRVELNF GVGVILCVDG
VVHRHLLSRD SHSSPQLKYE IRTGESVVKR NLRAQAALQT TPTPPAKYSF LSGSTFSSSI
QLNPVFDRSM DVPDFSFGPS NPRRPTFPSV VTSSDSRASP RSTQLERLHR RSPSPRISRI
NTSMLEESDE RNDAEAESTL TKLEGEDTRM VPQLFDRLCR TLCVEPDQNV SYLLPSNRIG
SNFTPAAALL MTEKSASQYG QLTKHSGGVV FIEKPSFLSS SFRMRRKKLL QNSPPEQRYF
EYLSDDKVID RSYLAPLPAD LEARVVAAAV KYIDGPSSDQ IERVLEVAHQ EFVYNYYASA
KKAILNYLLM RSESCDRLGI PQGAPTQARL PIKWKWGSSD GPNGCMADLN KAARRKRVQS
KLMSLLILSN PQVRALRHMW HGIYASITLV DLPGIEGHND GIEPMDIIEF ERAQLGFSAK
AKEFVMENWY MKSKMMFESA IRAETFSIHT SEAAVSFRLR HLFDTVAAVM SLQIRSLIMK
SIQAYVSFFE RYGGVNEENY ANSRDEERPA FPGLLTTLVL HGGQIQFRDP LVDIPSRLLN
VLHNIPKQFS NLGRIETQFE EPIVLSTTST PFLWNVAAQE DDIVVATIRI RAIIEQNLSH
LRKLQADYDM FALTHRYVNS VDCFHLEENS ELETYRAEME RVQTTALRLA IDNRHSQHLG
LFSVDCRQVN KRLHTDLAQW TIRLLQAFEQ RTGRINAELR QQYKEIAARL AKKPLDLYEL
VDGEAFVKSL KSAMLQELQD KANIIKQRLR FLLFERENIH IGNVEVDDVP TEHEGFSLSL
DLLSSTAKTL KWRSQIEKLL KEAESVLVDE RSRIESMFIA KRSRFQAEIE EFEGEVRGFA
KKGDLRHAAT YVIQLAKMQD NIFSFRQAMA TIIQEEQKLQ WKPTDFGKLD DIAEEMAPYE
RLWKTVREFR EMNSRWLRGN IFELPGKEGM HTLQQMLTVV SDVSSMLILN SAAAAITAET
VRKQMADFRE TVRLIVAIQN PSMKERHMKA VSGLLGIDFM SEELITLLKL LENGAFERIS
DIVDISCNAT QEQQIERALH EIRDEWETTS FKLVPSRHPI SLSTVLAPLL KTDDPESETF
NLVLEKECGG KIVSIMEDHL LRLQTLSCMS HAGPFIDEIA LWQTFVSEMG QVVEMLTLVE
HRWRKITPLF AAGIVENDST SSRLFASAAT LYQLSHAFIL RKPACTEYYM RSNSTVGLDQ
ALHSPARSLI SDLEQCQEIL DSLRGDVRVG FDSKRASFSR FYFLSDLELV TALALADVPS
DASLWKALSR CFPGIHSVQT NAANEITALL SSVGEPFPLG SPIITKDTPM PTWLAKLETS
MTTILHASIR AAYSDLPRKE FRKWCLIWPE QSLLAAIQHV WTLQSEQAYQ NPNQRKAWTA
VTDNLIQNID AVSKEMRVTA YPHAKVALGN IILLLAQLRD VSTSALAEVG GTWVEERGES
KCESCTYPHY SPSLCWIAQP RYYFIDSVLS VTMMTSLNLP YGLEYLGNGS AGMLVTPLTL
RCFHAIAQAV STMVKGACLE GAAGVGKTTI CHQLARLCGR LDVTFQCANR ELVFDELVNY
IKATTSSGAW LCIDNFQLLD PVNVSMVTML CAQVMSGLAA RHAQCSLVGD RSPDIEKLAE
FEFQCARFVH ASDLSKLLVA ALGACERGFE LMSHSSETTN AVNVLGSRLV NMRLVKSVVK
RAMELNNLEK EHHRRGRCSL LISDEEHEDV STTETPILND ATAEAMAKRD EERMEHRSVY
LAIQECMGSV ISAANFQLIN SILRDFSSDA LTGDLDTLNN EGQGNFGSPS LSTTGLVHNL
ENYVENYVRT NEEWKHFGVE FGMKMVQLLQ VMRNSRAVVL SGEVLRTELA LVK
//
