ID   W2KZH6_PHYPR            Unreviewed;      1031 AA.
AC   W2KZH6;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   27-MAR-2024, entry version 46.
DE   RecName: Full=DDHD domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=L917_10798 {ECO:0000313|EMBL:ETL90558.1};
OS   Phytophthora parasitica (Potato buckeye rot agent).
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Phytophthora.
OX   NCBI_TaxID=4792 {ECO:0000313|EMBL:ETL90558.1};
RN   [1] {ECO:0000313|EMBL:ETL90558.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CHvinca01 {ECO:0000313|EMBL:ETL90558.1};
RG   The Broad Institute Genomics Platform;
RA   Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA   Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA   Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA   Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA   Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA   Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA   Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Phytophthora parasitica CHvinca01.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KI680327; ETL90558.1; -; Genomic_DNA.
DR   AlphaFoldDB; W2KZH6; -.
DR   EnsemblProtists; ETL90558; ETL90558; L917_10798.
DR   VEuPathDB; FungiDB:PPTG_13399; -.
DR   Proteomes; UP000054423; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR   CDD; cd00821; PH; 1.
DR   CDD; cd06093; PX_domain; 1.
DR   Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR004177; DDHD_dom.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   InterPro; IPR001683; PX_dom.
DR   InterPro; IPR036871; PX_dom_sf.
DR   PANTHER; PTHR23509; PA-PL1 PHOSPHOLIPASE FAMILY; 1.
DR   PANTHER; PTHR23509:SF10; PHOSPHOLIPASE DDHD1; 1.
DR   Pfam; PF02862; DDHD; 1.
DR   Pfam; PF00169; PH; 1.
DR   Pfam; PF00787; PX; 1.
DR   SMART; SM01127; DDHD; 1.
DR   SMART; SM00233; PH; 2.
DR   SMART; SM00312; PX; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   SUPFAM; SSF64268; PX domain; 1.
DR   PROSITE; PS51043; DDHD; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
DR   PROSITE; PS50195; PX; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT   DOMAIN          444..591
FT                   /note="DDHD"
FT                   /evidence="ECO:0000259|PROSITE:PS51043"
FT   DOMAIN          769..863
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   DOMAIN          903..1017
FT                   /note="PX"
FT                   /evidence="ECO:0000259|PROSITE:PS50195"
FT   REGION          698..717
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        700..717
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1031 AA;  117438 MW;  6847558C3D827EA0 CRC64;
     MSAVAFSSAE ELPERSFFPK VYMHQYRQQL SELLKRLELL LDEDELLEVD YDGEPVSALP
     RESVWQNLCT LQNCSVTLSD VMGQFKQKIQ ESAAVDPGAF ELERTQSSSS IDCSSSDDVD
     EEIDVGFHDV EPVKGRKAAV ALNNDVTERV ENALRDDEEF DRFKANALEF GMGHESAESF
     YAYLAQHIPA PVLDSIVVDF ARLLPQPALR VPLLKAHYEH MQNELSRPSI ASFKNKSYST
     VLTSRSSTSS SIDEAGSSDD EDEEYPSTIR LRTFNHLVFV IHGIGQHIDF RDGEFKSWNG
     ETGVEGGNHA FRDMFRSMLE TTFQDIPLAL EMQSIEWHED LHDPTGLDNV FDLISPEGAS
     AIREFNKETF MDVLYYLSPR YGQLIVDSVT QQLNEKYRVF MDEHPGWDGK VSIFAHSLGS
     MISYDLLTHK PGEVAINGVR FPGLDFEIDN FFGVGSPVGV MILARGDLNI EDGEFTPGIK
     IPNCRRYFNV YHPIDPIAYR IEPLIKQEMH DKDPVQLMQF SAVKDQTFGQ LQEQWEGLNG
     PVHGFPYRHD YVMRRRKREQ GMMEVAFAAA SHSSYWMSDD VVLFTIMQLC QPVVDTLHRY
     MSARVPLPKL MRSIVELTPH TKVLLSATAL VRDRCTGLSR EQIVLIDKDR LYFLSRLSEV
     ACRRKWRIKL TATTKAVYGE DSFMMKIIPN DAAVPEPGAP PTSNNATQPG VHTFKAPSTP
     VRNQWMDAIN EAVVKANSIL AEELPAHKVT RDTANLVDLP TGKSIDYFNA IKAGFLKEKT
     ANGWYDSWND RWLVLQEDHL SCYENSPKLD FVGQFPLRKT KAFCYEREYL IRVVARRGAA
     CEMRVQNQES FNRWVEVFEK IPTVEIYRHK DLLENSPSSV LIMTESSRGH FNGAQKKSKG
     GEWLQTKIEG HQIKLDENDQ EYVAFVIQVA SSTAGHSIVQ RRYSEFAKLH RELRKLFQPE
     QLPALPGTRM WNKFEPNYLK QKAIGLHGYL NEVCKRCANT RAQPLLLDFL ELTPPATELK
     ESTEEENAEK N
//