ID W2LRL7_PHYPR Unreviewed; 564 AA.
AC W2LRL7;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=Magnesium and cobalt transporter CorA {ECO:0000313|EMBL:ETL99349.1};
GN ORFNames=L917_03815 {ECO:0000313|EMBL:ETL99349.1};
OS Phytophthora parasitica (Potato buckeye rot agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=4792 {ECO:0000313|EMBL:ETL99349.1};
RN [1] {ECO:0000313|EMBL:ETL99349.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHvinca01 {ECO:0000313|EMBL:ETL99349.1};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Phytophthora parasitica CHvinca01.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35)
CC family. {ECO:0000256|ARBA:ARBA00009765}.
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DR EMBL; KI678376; ETL99349.1; -; Genomic_DNA.
DR AlphaFoldDB; W2LRL7; -.
DR EnsemblProtists; ETL99349; ETL99349; L917_03815.
DR VEuPathDB; FungiDB:PPTG_08116; -.
DR Proteomes; UP000054423; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0015693; P:magnesium ion transport; IEA:UniProt.
DR CDD; cd12822; TmCorA-like; 1.
DR Gene3D; 3.30.460.20; CorA soluble domain-like; 1.
DR Gene3D; 1.20.58.340; Magnesium transport protein CorA, transmembrane region; 2.
DR InterPro; IPR045861; CorA_cytoplasmic_dom.
DR InterPro; IPR045863; CorA_TM1_TM2.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR002523; MgTranspt_CorA/ZnTranspt_ZntB.
DR PANTHER; PTHR46494; CORA FAMILY METAL ION TRANSPORTER (EUROFUNG); 1.
DR PANTHER; PTHR46494:SF1; CORA FAMILY METAL ION TRANSPORTER (EUROFUNG); 1.
DR Pfam; PF01544; CorA; 2.
DR SUPFAM; SSF143865; CorA soluble domain-like; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF144083; Magnesium transport protein CorA, transmembrane region; 1.
DR PROSITE; PS50222; EF_HAND_2; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 502..526
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 538..558
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 142..177
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 1..47
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 30..47
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 564 AA; 65100 MW; 10CD030905F62BCD CRC64;
MPGPMDFYPV DEDTPLLRGP EESPRNPDFT SYPVAANSGD SSTTRRSLQT TELELNVDKI
SFLFSPSARH GYGSPNNYKS FADVPLHGSV QDVDELNMLD PYFDVTPPRL RVAFEGAAPE
EGGELSYDGF RVALETLGIR CSDNSVFLKL VQSIDREQSG QITLQQFDAA VHRLKLMHMF
DEGTVQEMRT VGYQQAALSV SDFSSTRLQS FALRQENLHE FFTAHRPEWV NVRWINLDGR
DSLNLKRLAI KYRLHPLAIE DTIEGHERPK FDRYDGHLFL VFPVLRMQLA DKGNRLYSDP
REPSLPTFVK RMSFRRSMSA VTDETDEEDD DPFKLWIEHV FIFVVDNDTV ITVKDGGDSD
IWTELNRRLA VPYSKLRHND AKFLVYSVLD VIVDQVTSVV DSITECLIAL ENQLEQERHR
FELRSLRVLK NELFRLPRLL KAAREVLKNI IESKDFDATV TDYVRDVHDH VVVALDDIEQ
QLQMCRQLTE EYRDAKANQM NYVIYTLTVV TTVFLPGQFL TGVYGMNFDE MPELHERYGY
ALFWVFAIAI AAALQLYFRY KQWI
//
