ID   W2MX94_PHYPR            Unreviewed;      1272 AA.
AC   W2MX94;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   RecName: Full=EF-hand domain-containing protein {ECO:0000259|PROSITE:PS50222};
GN   ORFNames=L914_13271 {ECO:0000313|EMBL:ETM40905.1};
OS   Phytophthora parasitica (Potato buckeye rot agent).
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Phytophthora.
OX   NCBI_TaxID=4792 {ECO:0000313|EMBL:ETM40905.1};
RN   [1] {ECO:0000313|EMBL:ETM40905.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IAC_01/95 {ECO:0000313|EMBL:ETM40905.1};
RG   The Broad Institute Genomics Platform;
RA   Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA   Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA   Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA   Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA   Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA   Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA   Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Phytophthora parasitica IAC_01/95.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the parvalbumin family.
CC       {ECO:0000256|ARBA:ARBA00009753}.
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DR   EMBL; KI694273; ETM40905.1; -; Genomic_DNA.
DR   AlphaFoldDB; W2MX94; -.
DR   EnsemblProtists; ETM40905; ETM40905; L914_13271.
DR   VEuPathDB; FungiDB:PPTG_14040; -.
DR   Proteomes; UP000054532; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   Gene3D; 1.10.238.10; EF-hand; 1.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR   InterPro; IPR002048; EF_hand_dom.
DR   InterPro; IPR009305; Mpo1-like.
DR   InterPro; IPR008080; Parvalbumin.
DR   PANTHER; PTHR11653:SF10; EF-HAND DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR11653; PARVALBUMIN ALPHA; 1.
DR   Pfam; PF13499; EF-hand_7; 1.
DR   Pfam; PF06127; Mpo1-like; 1.
DR   SMART; SM00054; EFh; 2.
DR   SUPFAM; SSF47473; EF-hand; 1.
DR   PROSITE; PS00018; EF_HAND_1; 1.
DR   PROSITE; PS50222; EF_HAND_2; 1.
PE   3: Inferred from homology;
KW   Calcium {ECO:0000256|ARBA:ARBA00022837};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        117..136
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        148..166
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        201..220
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        270..293
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        591..609
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        616..638
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1099..1119
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1139..1157
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1164..1183
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        1195..1214
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          879..914
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000259|PROSITE:PS50222"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1272 AA;  144919 MW;  D2D248D53CF5DD4A CRC64;
     MTASSAMESH ENDSPPTHTE VTFVTESPAE IKLRRTRNLT SSTDVADEIA TNMRINLDKR
     RKGFLSPSRL SATFRQNTEM ALRASFAVIL SSIIQTRNQA YDPSHAHDKK WMFFPDWYYL
     GGLSYCAIMV VFSMAYNVGG TIREVCQGFS GVGVALLYNY ILFAFVEVER FDSKADDPYI
     NYYKINKAFN SNAYWINVPN MYATLPWIFV FTVGVMVLPF HINTRKYAVG TNAYFTLTII
     NPANPLRSGQ LKSIDEELFD TSNILRNLRI FAIVGLLGAL ISVVAMCFPY PIFAISRLRE
     DSQKAAADLL ELLNIVVDSY CFKNKNVENM EFLKLRLRRK FDDAEARYRR MESLLEDAWW
     EQCFGLHYPL RFNRVMSRTY IKLVGSLIAD LRTLSYAMRL EKYGRLHTTY MAILKREIYI
     IQTRSNDLLN EISHEVHDLS PHLDLKSLGA LENQVEMALY QFRKIQNRTF AKEVVTPEEV
     AENVPLNLFL FSLNSFCSTL LNFQQSYNSR KYDDAHRVRS FVRKSLRKIV DPGYYKNPTT
     WINAFKITLA VMAGVGFSVG VYGFSSTVPS TIAYIMCETL GSSFRKTVNR VGGVVAGSIV
     PSVFKFFFVQ ICEPQVLSIV LTNIVMFIWV GMCMYVYFGQ GYAAYSGMVA AFVASDTLMR
     QTDICYPNGS DSSSSIAVAS YSSLAQTSVA VVIFISVETF IFPKSAISML RHSIVDSLKL
     HQKAFDELFG HHLSSSVVMD ESSMADVRRM LAVDIPNSLE KQRQLLVEAM VEPLLWRPNF
     SHDKYRRLLE ISQGLLNNNY LLFKLLRWFH FRVSQNRVNL SSSDIRDVVV RTDVDGDVDC
     HAKWKVSTAH FQSLVRDIFD TMKLVFCDTF CYADPDQTAV FMQMKEAFRL ADKDCSGELN
     ANDVTVMLGN IFAQSGDVKK EQIKKYVQEF MDVVGKPGRT TVSFEDFMDA LEHGLKLEIE
     VYHRVKPRPP ALLSSALQRA IKNEGFQEKY VDDNNVFEKS DTSKLAGTVG PVTVSELSQT
     RGTSSDSLEN ASVFIRREYD VLNVEDFTTS EVVAHMKAAY AEWLLTDNRY ERTSMEEQLL
     LNCLVTFYLS YHDNKINQYI HFACIWQIFI SALCMFASLE SFAEPPSFVT SLPYSQYMLL
     NPSCILAGIY MVWYIQLDRV AGSLGAALVF ICYLFANFFV QVYAPSNFER PGWQIALAVH
     CFAWIMQFIG HGVFERRKPA LFDSLDQALV TAPMFVLLEA MFAFGYRPEL YKRVSFAAKA
     NIKAFRAAGK TL
//