ID   W2NS64_PHYPR            Unreviewed;       391 AA.
AC   W2NS64;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding domain-containing protein {ECO:0000259|Pfam:PF02826};
GN   ORFNames=L914_05259 {ECO:0000313|EMBL:ETM50758.1};
OS   Phytophthora parasitica (Potato buckeye rot agent).
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Phytophthora.
OX   NCBI_TaxID=4792 {ECO:0000313|EMBL:ETM50758.1};
RN   [1] {ECO:0000313|EMBL:ETM50758.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IAC_01/95 {ECO:0000313|EMBL:ETM50758.1};
RG   The Broad Institute Genomics Platform;
RA   Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA   Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA   Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA   Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA   Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA   Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA   Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Phytophthora parasitica IAC_01/95.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KI691935; ETM50758.1; -; Genomic_DNA.
DR   AlphaFoldDB; W2NS64; -.
DR   EnsemblProtists; ETM50758; ETM50758; L914_05259.
DR   VEuPathDB; FungiDB:PPTG_09620; -.
DR   Proteomes; UP000054532; Unassembled WGS sequence.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   CDD; cd05300; 2-Hacid_dh_1; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR   InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR43333; 2-HACID_DH_C DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR43333:SF1; 2-HACID_DH_C DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF02826; 2-Hacid_dh_C; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   NAD {ECO:0000256|ARBA:ARBA00023027};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT   DOMAIN          177..356
FT                   /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT                   binding"
FT                   /evidence="ECO:0000259|Pfam:PF02826"
SQ   SEQUENCE   391 AA;  43295 MW;  C0A8F2E7708A664A CRC64;
     MTALTNPTDA DSLSSTSPLR VPIMTFIAGI GDNVRKAFAA SDSPAGELYR SGKLELIDIP
     LPQLVGNKQD PLHGPSMEDP GRPIWNLTPE QQSIVEQAEI VMIDSHGGGP VFMAPKENLP
     EDKQHVLNNV KWIQATYAGV DMYLDLLPKG PNATVPKFTL TRAGGMMPRI MAQYVLGYIT
     MIERKLLEAK EYQSKRDYAR VDMISFRPAQ SVTVGILGLG DIGQYTGKML RSCGYKVLGF
     KRHVSAQDVA DLAESADQIT TSLEEVLAKS DYLINLLPST SATRYVLNEK NLELCEHSPV
     FINIGRGDVI SEKTLINALN KGTLSKAVLD VFEKEPLPKE SELWEHPSVL LTPHVSGKVF
     PEDVAAMFLD NFNRYIKDEP VRYKVDWSKG Y
//