ID   W2P0D6_PHYPR            Unreviewed;       817 AA.
AC   W2P0D6;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   27-MAR-2024, entry version 38.
DE   RecName: Full=Glutamate carboxypeptidase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=L914_02212 {ECO:0000313|EMBL:ETM54452.1};
OS   Phytophthora parasitica (Potato buckeye rot agent).
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Phytophthora.
OX   NCBI_TaxID=4792 {ECO:0000313|EMBL:ETM54452.1};
RN   [1] {ECO:0000313|EMBL:ETM54452.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IAC_01/95 {ECO:0000313|EMBL:ETM54452.1};
RG   The Broad Institute Genomics Platform;
RA   Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA   Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA   Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA   Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA   Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA   Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA   Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Phytophthora parasitica IAC_01/95.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase M28 family. M28B subfamily.
CC       {ECO:0000256|ARBA:ARBA00005634}.
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DR   EMBL; KI691013; ETM54452.1; -; Genomic_DNA.
DR   AlphaFoldDB; W2P0D6; -.
DR   EnsemblProtists; ETM54452; ETM54452; L914_02212.
DR   VEuPathDB; FungiDB:PPTG_07160; -.
DR   VEuPathDB; FungiDB:PPTG_07161; -.
DR   Proteomes; UP000054532; Unassembled WGS sequence.
DR   CDD; cd08022; M28_PSMA_like; 1.
DR   CDD; cd02121; PA_GCPII_like; 1.
DR   Gene3D; 3.50.30.30; -; 1.
DR   Gene3D; 1.20.930.40; Transferrin receptor-like, dimerisation domain; 1.
DR   Gene3D; 3.40.630.10; Zn peptidases; 1.
DR   InterPro; IPR046450; PA_dom_sf.
DR   InterPro; IPR003137; PA_domain.
DR   InterPro; IPR007484; Peptidase_M28.
DR   InterPro; IPR039373; Peptidase_M28B.
DR   InterPro; IPR007365; TFR-like_dimer_dom.
DR   InterPro; IPR036757; TFR-like_dimer_dom_sf.
DR   PANTHER; PTHR10404:SF46; GLUTAMATE CARBOXYPEPTIDASE 2 HOMOLOG; 1.
DR   PANTHER; PTHR10404; N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE; 1.
DR   Pfam; PF02225; PA; 1.
DR   Pfam; PF04389; Peptidase_M28; 1.
DR   Pfam; PF04253; TFR_dimer; 1.
DR   SUPFAM; SSF52025; PA domain; 1.
DR   SUPFAM; SSF47672; Transferrin receptor-like dimerisation domain; 1.
DR   SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils}.
FT   DOMAIN          237..300
FT                   /note="PA"
FT                   /evidence="ECO:0000259|Pfam:PF02225"
FT   DOMAIN          422..520
FT                   /note="Peptidase M28"
FT                   /evidence="ECO:0000259|Pfam:PF04389"
FT   DOMAIN          692..814
FT                   /note="Transferrin receptor-like dimerisation"
FT                   /evidence="ECO:0000259|Pfam:PF04253"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          103..123
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          715..749
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   817 AA;  89803 MW;  E86C48D5D660443C CRC64;
     MMPLTTPLAS PGPARTRYDD HETLEDPSEV YGTFHGREVP DIGERPHVSS KLWRSVGIAT
     LLLVVASYML LQSHYDSVRG REESKTSSIS SLVAPEVHQK AQNEVHETTT FSHKHKDQDE
     SDGLSKLESK FLDSVDTTEI RKFHGAYASA PHPAGSHQDY KTALFTAEQF ESFGLKAEIV
     EYYPLLSLPI HRKLSILAPS EAARELNLTE ASIPGDSCTS NDDALPPYLG YSDSGNVTAS
     VVYVNYARPV DFQWLKDNNV TLEGKIALVR YGGNFRGLKV MLAEQHGMAG VLIYSDPLDD
     GYAQGPVYPE GPWRPEGSFQ RGSVQYNSIY GGDPLTPGFP SLPGEPYLSK EECKTIPHIP
     TLPLSYGQAR YILESLGGKK APQSWQGALN LDNGGYFVGD DDATVLNLDV AMDNSIGPIW
     DVIGTIEGTE EPDQMVIIGN HRDAWVCGAV DPSSASAVML EIARGLGDLL KDGWKPRRTL
     VIASWDGEEL GLLGSTEFAE DHAELLKKQA VAYVNVDNVV GPFVSSGGTP SIAKFLQETA
     QLIPGNPFHG VEVTENLYEQ WVSQTAIRRS SLAAGVDDGT MAPDHLIQFL GSGTDFTAFY
     QHLGIISANL GYTVGTAMYG TYHSTMDSIP YMETVGDPHY ATHTTMAKWW GLITLRLVDN
     AIVPFDFSTY GLVMQEDLAG YEKITTEMGR HVDYAELHEA IKKFSSNAEV FQARIAEFAK
     KNPKKKKEIR KLEAERHIWN EKLVSLERYL LSDAGLPHRP WFKHMIFGPG FYEGYKGAAF
     PGISDCIVFE DDDAAIQAHV DDVAAVINTA ATFLTSN
//