ID W2PPB1_PHYPN Unreviewed; 1034 AA.
AC W2PPB1;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 03-MAY-2023, entry version 43.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETN02104.1};
GN ORFNames=PPTG_16755 {ECO:0000313|EMBL:ETN02104.1};
OS Phytophthora parasitica (strain INRA-310).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=761204 {ECO:0000313|EMBL:ETN02104.1, ECO:0000313|Proteomes:UP000018817};
RN [1] {ECO:0000313|Proteomes:UP000018817}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=INRA-310 {ECO:0000313|Proteomes:UP000018817};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Chapman S.B.,
RA Gearin G., Goldberg J., Griggs A., Gujja S., Hansen M., Heiman D.,
RA Howarth C., Larimer J., Lui A., MacDonald P.J.P., McCowen C.,
RA Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA Saif S., Shea T., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ETN02104.1, ECO:0000313|Proteomes:UP000018817}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=INRA-310 {ECO:0000313|EMBL:ETN02104.1,
RC ECO:0000313|Proteomes:UP000018817};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Phytophthora parasitica INRA-310.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KI669619; ETN02104.1; -; Genomic_DNA.
DR RefSeq; XP_008912487.1; XM_008914239.1.
DR AlphaFoldDB; W2PPB1; -.
DR STRING; 761204.W2PPB1; -.
DR EnsemblProtists; ETN02104; ETN02104; PPTG_16755.
DR GeneID; 20185817; -.
DR VEuPathDB; FungiDB:PPTG_16755; -.
DR OrthoDB; 2891601at2759; -.
DR Proteomes; UP000018817; Unassembled WGS sequence.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00051; EFh; 1.
DR Gene3D; 1.20.58.60; -; 2.
DR Gene3D; 1.10.418.10; Calponin-like domain; 2.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR001589; Actinin_actin-bd_CS.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR PANTHER; PTHR11915:SF435; SPECTRIN BETA CHAIN, NON-ERYTHROCYTIC 5; 1.
DR PANTHER; PTHR11915; SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN; 1.
DR Pfam; PF00307; CH; 2.
DR Pfam; PF13499; EF-hand_7; 1.
DR SMART; SM00033; CH; 2.
DR SMART; SM00054; EFh; 2.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF46966; Spectrin repeat; 1.
DR PROSITE; PS00019; ACTININ_1; 1.
DR PROSITE; PS00020; ACTININ_2; 1.
DR PROSITE; PS50021; CH; 2.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 1.
PE 4: Predicted;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000018817};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 117..223
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 232..338
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 900..935
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 30..107
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 598..625
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 41..55
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 71..95
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1034 AA; 116898 MW; B97A0236669C86F8 CRC64;
MEFRAEECRS GTSVNRLKAF WQEQANREIA RQARSRSEPP RLIAATSTTT DRPRAVSHRG
VNPVQALLVA PKEQEEEEQE TKETAEDRVE PESEPTPSPL RDSTTDSMAG YNEEWVDVQK
NTFTRWANTY LSRKRMTIDD LYEDLKDGIR LISLLQIICR EKVCRKFNKK PRMRIQKMEN
LNFAFAFMQK KNVNVTNIGS SDILDGNNKL VLGLMWTLIK AFQVAEIDVE GVSGKDGLLL
WVNRSLADYP TVEVKNFSGS WADGMAFCAL IHRYAPTLID FNSLNPKDAQ TNVKLAFDIA
REKLRIPQLL EVENVAGQAK PDEKSITTYV SLLFKEFASG VQKKKAVTTI SKALNIAQRH
QELAAEFNKN ASGLLEWLQQ QTERFQTLSQ PRHIPDIKEA LARHLEYKKN EKPPREAQFV
AVEGCAGRWI ASCKNNGRAV PNLDPPIEKL QAMKAHLDEL ETAFELKLRQ NLESYQKTEI
FLKKVVKDLE KVEAWAKEKE ALSLFAEDLR VTSTADAEEK LESVAFLQNI ELPRYKQLLA
TVVSEADGLS EEHKDTKATL ERVEAMKNFV AMAEDKVEGV KIRLQECLRV QQDMDAVAKD
AKTLMRNLKY VIEEMDEEVE AATKLQDVST AGVVAAKHQF DTVLVPKVQN AVVSENEKLI
EKKQILAEAG RESDVALIEK TNARVQKLLD SLAEKRGYYE QELATVEKRD EVCREFANLS
ARIKERCAQS TQSINVVEGS LKDQFNSMVK LRHRLFRANT GVALEEEIEE KPEDPEITGV
ETSAAQEVAK PAAESVAPES EEGDKSTDVA TEVEEAKAKQ VEEVKAKAAE IITPLTEDME
KLERIHEELE RLQVHTNPFT TDTIHGLRAQ FTSLETAVRD KVKSLEKELA LSEVGSLTPE
QAKEIKEVFD HFDLDNDGVL ARDEFIMACK GLGLSLSEDD CHDYFDKIDE EDNDEISFEG
FATFCTLQLQ SGSTKDDVHE ALDILTGDEL TLEQIEERFD ATQVEFIKKH LPELLEADGK
SVDTDKFTDF IFSV
//
