ID W2PU23_PHYPN Unreviewed; 2831 AA.
AC W2PU23;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 24-JAN-2024, entry version 44.
DE RecName: Full=BEACH domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PPTG_23615 {ECO:0000313|EMBL:ETN04458.1};
OS Phytophthora parasitica (strain INRA-310).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=761204 {ECO:0000313|EMBL:ETN04458.1, ECO:0000313|Proteomes:UP000018817};
RN [1] {ECO:0000313|Proteomes:UP000018817}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=INRA-310 {ECO:0000313|Proteomes:UP000018817};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Chapman S.B.,
RA Gearin G., Goldberg J., Griggs A., Gujja S., Hansen M., Heiman D.,
RA Howarth C., Larimer J., Lui A., MacDonald P.J.P., McCowen C.,
RA Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA Saif S., Shea T., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ETN04458.1, ECO:0000313|Proteomes:UP000018817}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=INRA-310 {ECO:0000313|EMBL:ETN04458.1,
RC ECO:0000313|Proteomes:UP000018817};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Phytophthora parasitica INRA-310.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KI669604; ETN04458.1; -; Genomic_DNA.
DR RefSeq; XP_008910385.1; XM_008912137.1.
DR STRING; 761204.W2PU23; -.
DR EnsemblProtists; ETN04458; ETN04458; PPTG_23615.
DR GeneID; 20192214; -.
DR VEuPathDB; FungiDB:PPTG_23615; -.
DR OMA; LWVERTR; -.
DR OrthoDB; 5478899at2759; -.
DR Proteomes; UP000018817; Unassembled WGS sequence.
DR CDD; cd06071; Beach; 1.
DR CDD; cd01201; PH_BEACH; 1.
DR CDD; cd16449; RING-HC; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 1.10.1540.10; BEACH domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR000409; BEACH_dom.
DR InterPro; IPR036372; BEACH_dom_sf.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR023362; PH-BEACH_dom.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR InterPro; IPR001841; Znf_RING.
DR PANTHER; PTHR46108; BLUE CHEESE; 1.
DR PANTHER; PTHR46108:SF4; BLUE CHEESE; 1.
DR Pfam; PF02138; Beach; 1.
DR Pfam; PF13385; Laminin_G_3; 1.
DR Pfam; PF14844; PH_BEACH; 1.
DR Pfam; PF00400; WD40; 1.
DR SMART; SM01026; Beach; 1.
DR SMART; SM00320; WD40; 3.
DR SUPFAM; SSF81837; BEACH domain; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50197; BEACH; 1.
DR PROSITE; PS51783; PH_BEACH; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00175};
KW Reference proteome {ECO:0000313|Proteomes:UP000018817};
KW WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00175};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00175}.
FT DOMAIN 151..189
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 1841..1991
FT /note="BEACH-type PH"
FT /evidence="ECO:0000259|PROSITE:PS51783"
FT DOMAIN 2014..2321
FT /note="BEACH"
FT /evidence="ECO:0000259|PROSITE:PS50197"
FT REPEAT 2617..2658
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 738..764
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1677..1753
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1884..1905
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2335..2364
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 750..764
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1693..1720
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1721..1735
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2335..2357
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2831 AA; 312465 MW; 1FECC3B9340000F1 CRC64;
MMLSLCHERP RNSKKSKKAD RSSRARSITP SDSHASVLST EIFASPVPTL MRLLVKMTSA
TFERAKGAPG IEFDVSKDGY GCLQIPDVNA RSSSSIEPAT TTPSLSTFAH SSKVWPPPDG
YSVMAWFRVD SLDRKDDREK LYRECFMSNT CIHCRNKIQD ECVLKCSHRA CRGCIEALLN
SGGECVVCNP PMFYIFRFRS SDGKSVSEAF LKGGKLYMRT SSNRASAYQF SHTPITTGQW
YHVVFTHARQ RFQSSMVSCY LNGILQENVK ISYPSGITGS QPLSGLLGVP SQARRCSSAK
WMLGPFYLLD LPVSPPVVNA VFAAGPSYDR LFFGATGSNE IGVTFDHLSI PNMVMLDSYM
WDPVRSLIDS VDVERGGRNK LLRRSLSLAS AASSTAAAIV QDIKSSSNVF ARIPSAAPLI
HIPIPSERIV VTYSARNGVA KELSMVPSSK LDGRPSGHLM GGTTLCEAAT MADAMFDIRT
SGCQIAYGLL DEASTKEEVE LALDLLRLCM QSNFRNLAAM ENDHGYGVVN YLLHQKASLL
SATCLQTLFR IVGVDFELDA PVRQSGIEAH HSRDSAIRNV QALQYFILDY SLWQKLPGAD
TAKLLFSTLY ACLAAADEAI RERNRAQLQS MSFIRQLLYV LMDPTVTDGV SRVVVDVILV
CLTSPSRDSI VESNFSDVTS FLAATLSPRF GRYRSEVVDD EISAEVVLAT MSDDEKFDVT
ERNTGQFKMH TLASPTGRLC LSPRGSQRMD SWSDTKDSEE KPGPTKVANA RLISHQAKIQ
ELLLDALVKA VHKLDIKENR ENGEDLDNGT SEMNSVGALK AMAPSSNSAG GAARMQLPTA
SRLTGFRKYL GMRWIEYFLF PGEETEFSLC IPPSTIIAAL RLLCTLLGNS RYENVFKKEG
YYRLLAQGLP CNHIAFATAA VDQILVPFPF QKMWYTLFGA LLGTPIDGVP TEIRLEIDYL
RKDFEVNIQR DRVVNFSILN VIMVLLRRHF NDPVAMMSTA GDMLMVSIVD VDGEPDQKSA
GPQSAVTSAS TELNDIHQVE VLDFLHHIFE NMPSLHSFVV SGTEKMRQEF MEELTRLICA
AARAYLIDQY PHSQGQVTKV LEDKQIALTE YNIAVARAEL AEEAAAADSN GSDPFLHHSV
SASGLRLLIA QLMKLLLDAP NGSDFVEEYV DGTANSAVVL PPLHSGLVLR FQSLVVMGLL
DHIRAKFDDD DILAKHKHFG ANVREFVKFV VGKMHSWQRP QHGDGCPAAF ACCGRAHFVG
GPSRLLEMVL FVLADANIGT CGTSGGGLSV LSTSSSFGGL LSEKLGKGKK RKPFRQLMDR
MTRSAELENL LFELFTALNA VILHVIHGRG AEVGDEELEA MLQQIHSHRE TVFGSQNTHD
KRFLGCLCRY LLQLLSDSNI RPLQEAAAHL WIDLMVFQRT FVDDLLTVEI RKSGAPPYSV
NLMKNGFDVL LECADTPEGR QIVQSSSFAK FSKWLELVGP PLKELENILD RIYINFVVET
KESVHETWAA YHKKANHRKI KYEKQFEARC DWFVSMENAY VESLLRSQQH EFRRQLKWKQ
DRVDRQKFVA RQWGRLHLDF QRDALADGKA KEQKVGVNAS DNPLLMVEIV NRTRYDIKAS
SPQHYCWRLD FTEGPYRMRK RLTRMAQTLE FPRFRGQQSS PARLCETSNK MKPRISALAP
NGDFHGSGRL QRRYSESDVN LSATISREKS PSGTAAHLST RQRSDESEVG KPRHPAAKRP
FATSASSSAV LSSRERLRKG SFEALFNKYV KNERRPSQSF RFNRLSAGHD SIVEHDASAD
NEEEKAGDVG GVESSTAESA ANAGGVVMED VVDEKLRPLL MPGDEIADIY DCLRIDGMDS
CPGVFLLCND HVYIVDNYQR QSQPFTSSHT DNGSEHNSQV RVTEVPQGST TLLERRLSWR
VLESPHHSQP VSRSRDTHQC RFWAYEDIKE LHKRRYQLRH VALEFFANDG RNYLVTLESL
EQRELVFHAL LAKCPNVQGA ASGLDGVSGG GDLYSQLRKL LRNSMTERWV QGDISNFAYL
MHLNTLAGRS YNDLTQYPVF PWVLADYESE ILDLSDPNAY RDLCKPMGAL QREEEFRARY
DGLLESLGAA DDDADDHPLS SRPFHYGTHY SSAAITLHYL MRLEPFTSHF RRLHGGKFDH
ADRLFTSVVG AWKSAAGFEG AQNGTQDVKE LIPEFFYLPE FLENVNKCVF GTSQTGVVVG
DVELPPWANG SPTEFVRLNR AALESPYVSA NLHHWIDLIF GYKQQGPAAV EACNIFYHLT
YEGSVDLDAI TDASTKRAIL DQITEFGQTP SQLFRTPHPV RAVSASASSN TATNSSLFGG
SLGPSSGASN AQGDSGDGRR VATSPVTTRA ALASSFLEGG EIISRMQTML SSGPVLSGTF
VGTTETTFSP ALETSAMLQQ DPRRQVPVNP LLAFYRRGQQ NSASCSNTSI HHIAWTSGGV
AREEKVVAVG PKCLLIPPRN NEYLAWGFHD RSVKVVSTGS SEIGGHGSES KVVACLELDV
EIDVATITTD GRIVITSSPG LPVMRVWRFN STRRSLAASL AAASGSSSAS ATSSSAAAVA
SSLAAASALS APHRRRTYTT MGPSSTRSLT LMGSVATPTH QHQITALQAS RAYSVLVSGC
AGGVAVLWDL NRRRFIRQLP PISGQDSGRV HSITTICINE VTGDIVVAAG STFGVYNING
VLRVRLDDTV VVFQDPSALS PVAITSMAVN RGEACEWSAE KHVVTGHADG TLCVWAYSQS
GGRDQSEQPQ QRRKDEWVIE LQGRHKVTPS SAITAICVTP DKRKLFTGTQ DGQLSCWTAS
TSNSSPTAAH R
//
