ID W2QKQ3_PHYPN Unreviewed; 714 AA.
AC W2QKQ3;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=PX domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PPTG_08055 {ECO:0000313|EMBL:ETN13129.1};
OS Phytophthora parasitica (strain INRA-310).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=761204 {ECO:0000313|EMBL:ETN13129.1, ECO:0000313|Proteomes:UP000018817};
RN [1] {ECO:0000313|Proteomes:UP000018817}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=INRA-310 {ECO:0000313|Proteomes:UP000018817};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Chapman S.B.,
RA Gearin G., Goldberg J., Griggs A., Gujja S., Hansen M., Heiman D.,
RA Howarth C., Larimer J., Lui A., MacDonald P.J.P., McCowen C.,
RA Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA Saif S., Shea T., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ETN13129.1, ECO:0000313|Proteomes:UP000018817}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=INRA-310 {ECO:0000313|EMBL:ETN13129.1,
RC ECO:0000313|Proteomes:UP000018817};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Phytophthora parasitica INRA-310.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KI669575; ETN13129.1; -; Genomic_DNA.
DR RefSeq; XP_008901206.1; XM_008902958.1.
DR AlphaFoldDB; W2QKQ3; -.
DR STRING; 761204.W2QKQ3; -.
DR EnsemblProtists; ETN13129; ETN13129; PPTG_08055.
DR GeneID; 20177884; -.
DR VEuPathDB; FungiDB:PPTG_08055; -.
DR OMA; KHNIGFS; -.
DR OrthoDB; 54753at2759; -.
DR Proteomes; UP000018817; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0043226; C:organelle; IEA:UniProt.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR CDD; cd06093; PX_domain; 1.
DR Gene3D; 2.60.120.680; GOLD domain; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR009038; GOLD_dom.
DR InterPro; IPR036598; GOLD_dom_sf.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR PANTHER; PTHR23324; SEC14 RELATED PROTEIN; 1.
DR PANTHER; PTHR23324:SF83; SEC14-LIKE PROTEIN 2-RELATED; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF00787; PX; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00312; PX; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR SUPFAM; SSF101576; Supernatant protein factor (SPF), C-terminal domain; 1.
DR PROSITE; PS50866; GOLD; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50195; PX; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000018817};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 674..695
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 56..175
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT DOMAIN 187..289
FT /note="GOLD"
FT /evidence="ECO:0000259|PROSITE:PS50866"
FT DOMAIN 408..517
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 294..330
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 528..623
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 538..552
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 584..621
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 714 AA; 78963 MW; 1317570F145BCB4C CRC64;
MMDINADPSE LNSSLPQATK AAAMTADMEE KTPPKGCKKQ LVACRIEGHK IQKRLSPKKK
ALDPLRYLPD HGGYYALFTI AAYFEAEGDE ATERHHVVQR SYKQFCTLHS RLLKTYPKSH
LPKGLPAMRN KRYDNEYIEE KRNELTKYLA QLMQIPEVKA SNVLRDFLEA STAAEDSSDD
EDGLVTPSRM LEGLPGTIVT VRAGQSFSVT LPLSAAGDVA SWQFTTKKHN IGFSATFEGE
MIRAYSREGA DVKPVKGFYR CTTAGTCTLT WDNTYTWSKA KVLIYWAEVE SQNGTPQQST
QRHALTASAT SQDGTVSTEN TEAALTGSGS DTVDMDNRRL GFIEHTRSNS MHPRHLVNSS
ISLLSKPFVH GHDDGSAHGK ARRLIPGRAT SAPALTIPSY LQASEHGPQV KAGSLIIQRS
VKFRGRNWYR KWFVLDPRKC VLRYYDSEAA ARRGLSLAKL NLTNKHASLA ITSSLSLDAA
PTPYMFLIRT KKHCWKICAP SQSEYNEWEN AISTAILTAQ LSRRGRKSKK AMVKAAKKSA
VVRKDSQASD SEDETPKAGA MTDINGNDVA TMSSCRDPDR PLSPIEESDD DDDDSDNKDD
GDSDDDDESE SDSDDELHEG DDIEVVQPIV DTGSPMHIQS EAVGSMPDLQ KLPLEWKLGL
AAVLNVALLS VRSAPTVVIV LVLFIMDWYL LLLYMKNTSD NELNSSSMAK PKTE
//
