ID W2R6J0_PHYPN Unreviewed; 1105 AA.
AC W2R6J0;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=4-coumarate-CoA ligase {ECO:0008006|Google:ProtNLM};
GN ORFNames=PPTG_21018 {ECO:0000313|EMBL:ETN20851.1};
OS Phytophthora parasitica (strain INRA-310).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=761204 {ECO:0000313|EMBL:ETN20851.1, ECO:0000313|Proteomes:UP000018817};
RN [1] {ECO:0000313|Proteomes:UP000018817}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=INRA-310 {ECO:0000313|Proteomes:UP000018817};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Chapman S.B.,
RA Gearin G., Goldberg J., Griggs A., Gujja S., Hansen M., Heiman D.,
RA Howarth C., Larimer J., Lui A., MacDonald P.J.P., McCowen C.,
RA Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA Saif S., Shea T., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ETN20851.1, ECO:0000313|Proteomes:UP000018817}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=INRA-310 {ECO:0000313|EMBL:ETN20851.1,
RC ECO:0000313|Proteomes:UP000018817};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Phytophthora parasitica INRA-310.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KI669563; ETN20851.1; -; Genomic_DNA.
DR RefSeq; XP_008893718.1; XM_008895470.1.
DR AlphaFoldDB; W2R6J0; -.
DR STRING; 761204.W2R6J0; -.
DR EnsemblProtists; ETN20851; ETN20851; PPTG_21018.
DR GeneID; 20189617; -.
DR VEuPathDB; FungiDB:PPTG_21018; -.
DR OrthoDB; 1404660at2759; -.
DR Proteomes; UP000018817; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:UniProt.
DR CDD; cd05911; Firefly_Luc_like; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 3.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR24096:SF149; 4-COUMARATE--COA LIGASE 1-RELATED; 1.
DR PANTHER; PTHR24096; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR Pfam; PF00501; AMP-binding; 3.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 3.
DR PROSITE; PS00455; AMP_BINDING; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000018817}.
FT DOMAIN 23..124
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 169..529
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 591..952
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 1003..1081
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 1105 AA; 120713 MW; C477DF2AABA79B19 CRC64;
MIFRSRLPTL PIPDDASIWK VVEDHARTIG NKKAFICGIT ERSLTFAELL EQAKKVCAGL
AANGLKKGDI VILHSFNCLE YVVVFLALNR LGAIISPSSP LFNGKELADQ IEIAEAAAVI
SHKKFAKVAV EAAGLRLFAS SVSTSPMIFR SRLPTLPIPD DASIWKVVED HARTIGNKKA
FICGITERSL TFAELLEQAK KVCAGLAANG LKKGDIVILH SFNCLEYVVV FLALNRLGAI
ISPSSPLFNG KELADQIEIA EAAAVISHKK FAKVAVEAAG LRRLPLSRVY TLGQAEGPSG
LKTIEGLIAQ NLPFPNIPPI DTNQVVTLPF SSGTTGRPKG VELTARAMYA CGLLPAYREA
DLEYVLGMLP FFHIMATMIF HVTLYKGVTM VVLPGFDPET FLRTVAKYKM TKLNLAPPLV
TFLAKHPIVD KYDLSHVTHV NSGGAPLGKE VEHAVMQRLG IRVLQGYGMT EFAGCATSSY
PTTYRDGASG TLHPNTELKV KDLETDEDLG VNQTGELLFR TPALMKGYYK NPEANREAKL
LLASWIHFSI RHFRANPFSS RLVNSSSMSI IFKSPHSDVS IPDDAAIWNK LEQHAHENGD
KPALVCGMSE RTLSFAEVFN LAQRICAGLY ANGIKKGDIV ILHSFNCLEY PIVFLALNRL
GAICSPSSPH FNSDELGDQM RASKASAVIS HVAFAEMATQ AAGRVGIPLN RMFTLGHAKG
ALGLQTIEAL IELNLPFPSL PRINPDDVVL LPFSSGTTGR PKGVELTARS MYACGARVSA
LDVDADYILA VLPFYHIAAT MIFHVTIFKR IAMIVLPRFE PGSFLRVIEN FKLDTVYVVP
PIVQFLAKHP LVDKYDLSSL NRLASGAASL GGELFDAIQN RLGLPVLQSY GMTELAGSAT
HTSRTEYRKG SAGKLLPNTE LRVRCIETGV DLPVNQRGEL LIRSPGAMKA YFNNPEATRE
AFTDDGFICT GDVGYIDEDD YIFIVDRLKE LIKYKGHQVA PAEIEDVVNS HPQVADSCCV
RGLDLETGGE IPKVFVVRKF SGDEPLTSNA LMEYVASKVA SFKRVREVEF IDVIPKSLSG
KILRRKLQLE QDKKVAAARS IKSRL
//
