ID W2RAY0_PHYPN Unreviewed; 4959 AA.
AC W2RAY0;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=UBA domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PPTG_02450 {ECO:0000313|EMBL:ETN22532.1};
OS Phytophthora parasitica (strain INRA-310).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=761204 {ECO:0000313|EMBL:ETN22532.1, ECO:0000313|Proteomes:UP000018817};
RN [1] {ECO:0000313|Proteomes:UP000018817}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=INRA-310 {ECO:0000313|Proteomes:UP000018817};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Chapman S.B.,
RA Gearin G., Goldberg J., Griggs A., Gujja S., Hansen M., Heiman D.,
RA Howarth C., Larimer J., Lui A., MacDonald P.J.P., McCowen C.,
RA Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA Saif S., Shea T., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ETN22532.1, ECO:0000313|Proteomes:UP000018817}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=INRA-310 {ECO:0000313|EMBL:ETN22532.1,
RC ECO:0000313|Proteomes:UP000018817};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Phytophthora parasitica INRA-310.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KI669562; ETN22532.1; -; Genomic_DNA.
DR RefSeq; XP_008891778.1; XM_008893530.1.
DR STRING; 761204.W2RAY0; -.
DR EnsemblProtists; ETN22532; ETN22532; PPTG_02450.
DR GeneID; 20172687; -.
DR VEuPathDB; FungiDB:PPTG_02450; -.
DR OrthoDB; 2916270at2759; -.
DR Proteomes; UP000018817; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008152; P:metabolic process; IEA:UniProt.
DR CDD; cd16449; RING-HC; 1.
DR Gene3D; 1.10.8.10; DNA helicase RuvA subunit, C-terminal domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR015940; UBA.
DR InterPro; IPR009060; UBA-like_sf.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR15600; SACSIN; 1.
DR PANTHER; PTHR15600:SF42; SACSIN; 1.
DR Pfam; PF13920; zf-C3HC4_3; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00165; UBA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 2.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF46934; UBA-like; 1.
DR PROSITE; PS50030; UBA; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000018817};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 623..668
FT /note="UBA"
FT /evidence="ECO:0000259|PROSITE:PS50030"
FT DOMAIN 4910..4946
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 3777..3861
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3790..3813
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3827..3859
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 4959 AA; 553836 MW; F1C6A1FB5D127FD0 CRC64;
MVDADVYFGD DFGQKIDLTV RIREILRNYP EGTSIFKEMV QNADDAGATE VNLCLDYRQH
AATGLAYEKL ASFQGPSLLV HNNATFSDAD FQSIQRIGDS LKKDNSKGWK TGRFGVGFNS
GTIICIPWIC FLQQKGQHLN VLVFLVCFDA VYHVTDLPAF VSGSQLVFFD PQACHLPNVN
PSNPGKMIDY IAHPNLVSNF PDQISPFRCF GCNFSEPFSG TIFRLALRTE EQAQRSKLSN
RAQTPAKMAE MLKEFADSLP TVLLFLRNVC KISIWEWRAG EDTPTVLHEA SISNMTSEIK
AMRSLKHTSL SSNHQPATQR FSTDGIVCDY PLNIEARHCT AGLTKKFEYL IMNQLGGGEC
SKIACDPANA SQRLVPWGGV AVSTTADSAN TATSGLAFCF LPLPTHTYLP VHVNGYFELS
SNRRDIWFGE GLSGDGLLRA QWNIALLRDV IAPCYVRAIL HLANNQVMEP RQHVQLLPQA
LPPAPWDSLT YAFFSLVRNK PCLYSEVGGG RWVSPSESMV IRSSYLNSKH LEQLLIDDGF
PVVRNLAEDL ERVLVKTGTV PSYVEPQTVR EAYKSKHSSH ADDQGAIKCL LSFMLSDLEP
SRLNTLVGVN FLPVADGTLR VFENRSKVVP NELEYLCSMG FTRQHAVFAL AVAGDNGVEV
ALNWLLQNPN PSIVSGEGAN ITLYIPNREE LELLEKARGH LMHIDAIGAD ELKLLSTVQA
QKQLNVQKLD FQGFEDMLAV VLPAAWFGKL VVPWSGTGER DEPNEEWFRH LWNYIGKSKH
LSSFNDKWPI VPTSSHKLAQ LSASAGVLSA ELIPEGCLEC LEKIQVRLLL PNLFASFQPN
PEVWQYIQQP TPAGVLSCIG VALGAGGLTL PAQAKALFER TEKSDREHLL KFLMSGDIED
IGASHKQICC KLPIFPGFRT IPRIEERGTQ WMNSEEEIDS LGSGFSPVFV SLAEIEEHHH
ESLLCVGIAP KFLDDNFVFV KEGDAVLAEF LAHLGARRIS KVELFAKHLI PRFNRIKPDA
RVKFVYQLLL ELSSLLAQDH DGILSSILET AAIFPTMTGD LKCIDDLYDP EIDEFMDIMD
DSFFPALDLQ DPQPLSALRS IGLQRTLSRR SILSLAVSLE NDQMKITAAS AELKDDAELE
ATCEKLRTRS VKFFQYVDIH MEQLVTPTSL QRKPQNHAKR SKKSKGMRFL RNFIGDDRLR
GLDSLHDDNV PTAEELEGQA MERAEIEDFK AKLAIIVWIP VYEEKPHPAA PWYKQGERII
VASSQQSRPT KQLWLCSSQF HIIKCSVHSE VLRDVLGWDK LVPVETIAAQ LKKISLLFDA
QRVQGCGELK SGADNDTHVI WSAVYNIYQV LSVFFETELG GRRSQVLAVL SGNGKYVWVG
DRFVSANHVA NVAVVNAEPY LYTVPNELLH FRPFLRAIGV RERFALADYV HVLGSMYKDC
SAGVTSEVGN TKAAPLSGDR LTTAIGLIQL ISDTLQHHSD YELFAPDRDG VLEFAASLTY
DDAPWLDEHD YETSSGSIRF IHPKISNEVA AKIGSRSLRN QLLNESGHEA MSFGDVEAFG
QTEALTKRIA HILEQYPDGP NIISELIQNA DDAGATRVAV LYNNCTYGTS SLLSPAMAKW
QGPALYCYND AEFSDGDFIN LARIGQASKL QRAATTGRFG LGFNSVYHFT DLPSIVSAKS
IVMFDPHATH LPGISAVNPG IKIRFANANI VKQFPDQFAP FKGVFGCDLE HHYKGTLFRF
PLRDSTLAES SEIKRRGYSH REIVELFKSF QASIIDTLLF LRNVRKVEVY FQPEIDQSPV
LLYDAEVPEE DRGESWREID RFMRNTESTS GTTELSAKRE FYARLRSTPT QELPSVSQVL
HIRRRQQKEL QDSFHRFGTV TSHQESEVEM DHRMEETTEK YLVCNQIGGG KARDMACAAE
NESLKLIPWV GIASRIDEEP MEGRAFCFLP LPVRVGLPVH VNGYFELSSN RRDIWTGDDM
SGDGKLRSEW NANLLVDAVA PAYLAFLLEA KAMSQGDFSQ YLPFFPTNLP ASPWDSVVLE
LFRIMKNQPM FFASPSQVMS NTLVEAPRRS VAPSSCVLVD DSLTDWETLE AALGTVSLAT
VHLPVALRNL LIQLNAVHGA MTPGFFRQLT RTGDFLSVLN QDGLKRVVQF CMSDCLGPSN
LLAAQALNQL PLLPLKNGKF ERLCFTDTND DTDSSRKQQL TFFFGNAIEE ELLADFQHRV
VRGEFKELFD QLPAVYENSN LGVVSLETIL ESFLPHVLGR CWSKIQKDMF ALTSTSAMDE
TQAKKDWIRL LWTYAETQLQ TLEQLPQSFM KWPLIPIVCD EGNRWVCLSA SISLVFPPSE
SSPLSPELLS QLQHVLAKVG VHIVDMSYVN GERSKQWLLA RKYTHKLTSN GLLAALSRHQ
FQHNRQSFDD IFAATTATER QVLCDFFAQN TFDTVSNDLQ PILFELPIFP VYRNSVFTAA
SAQDNNSAQF LSLRRGGYLP DTNADSRILD DSFFHAEKES LRRFLRDCGI DEWTDTRILL
DYVFPRLDEL EKRDGDLVDS VIVGALETLS YHQRNDSRFR DVIATQAVIP SRKRVFREVR
QLHDPSVSEL SDLVGENSLP AQAFSTPLMV QILRSLGLRT GLSCHAVLES ARSIEAMYGE
SSDDSANQAC VKAHSLLSIV NKHFDAMMSE TTSNDSIAEQ EENSERRAIL DIVAELKDVK
WLPVRLESPD PAMPWKRSTG SVDHRPTLSN ASKIRPLKDA WLCSSSMDIL DGELTSEELI
GAFGWNEQVD SFVIAKQLEA IAFQWEEYCR KKDAEASSTL PSWRFPLSEV HLMYEELESC
RLADEEAWKT SPVYRKLANA FWIWTGRGFA YPCQIAVEAD SALEPLLYSC PSEHIIPRSL
LASFGLKNYF DTVDYLEAIM RLPRNIVLHD KQVAACLKIY ETVADDTSSL ESALGSFVSQ
EMVLLDQSNR LVSAAQLTFD DMEWNDSREV RRGATFVSNK VPKTVAGLLG AASLHSTLAQ
TSVTSRRVVC PPVDALKSVL PLRSEWLHTL LWETILATER FGGSQVDFFL DSRHHSSQRV
IQPSLQPLQD EALCIHIHGL VLSENDINNL FQGESSRAGL LCGFTVSDCM QILSGEGFYV
LDPTGCYLSS SAGTTTSSAP ASGRITSVGR RYEVLSQDFV RYPDQLLPFT TLPSCPSNVS
QGTQSTLIRF PWRKSASAVS AYVLDTKEVD KLVAFLKSQL YHTLIFTECV HRISLWSVGK
ESEFASHCHG EVYLEAPERT IRKRNITRQN QEWKKRFSLQ SFFKTPQIPE NQMEFVVNLE
LENRQHRDTW LFADNIGWGR SRDLACTPVH EMLHSLPYVS VACHIFRDGK PAPRLRGRVY
KILDTHQKVG LPVHINGCFK KTIKDKQLVL AAPNQAGREG DSGGASGSEL QVAAGWNRIL
LEDGASDAYA KLLMVAKRRY ESSFPRALYK IWPTLQQQRG DKELGALVQA HTYHSVATRE
LFLCTDGVFR ALSSGYQLDL GGMNIQVASF AQLHFPAFNI PARILQDCSR LLPSRIYSVT
PRVMRRFLRS VSSSEVLSDV CLSLLEYCLS DLPFPLPSEA DPIWTEFHGL SLLPLEDGSI
GVLRVNQRRT SYILASFNQI ELLRPLGNMF VSLAAFQRLH KYFSETRFTS IFGLTSFSIK
TLADNIERVL PSSWKNRAVV DWDPSSPVEI DQLWLYRFWQ VVHFERRSLG YFANWPLIPV
KGSRLISCAK MDMAVCVWDG SADDEVAAKV AEAFLASTTE QDKKMAGMEA ERKRLMELSS
EKLKKEDELA DESSDDEERG EVDDDEDVAS DNDSVSASDE GDLTVEVEDI SSSTQGEERN
SNTESVVESG NSSGETPLSP GSLVVALEDI SNDEEDDESG GISEGFAVPV YPVEDESHEF
CSRETLHNIL LELNVSMMEL AYLGGQERDI VPRSAEVGLA VLDGVFASAW EELAWEDLTE
PCAVLIAEFF AHNGETNGGY NRAQLEKLKQ LPIFVNICDV PCAIHGGQDF FLIPTELNLT
DIPLPPDAQQ CFLKSNPRLN AFYKELGVDE MSDSKLLIYI LPMFNGLLES QRDQVMHILL
QKWQSLRGNA ELTTLLKTSA LFRDDESEGA SYHPASAYCD PRNKVLATIY ADVRGQFPAQ
RYRTPEWLDL MGEIGLQTEV TVEIFVECAL RIDGQFSGKQ ALAPEDEHLI TTLHEFFVQN
FDKFDRSRSF FDRITPLSFV PAVVYENELE SSNGAAVDRQ KREGQFTSRS VVRKYADCAT
SDDQALVYST MPILANVALP PRVLYSRLGI KSPPPQDQVV KHLLTITNGD RAMSSRSLDW
QFFLPMVEVF QAIFKFLQEN WVELGPETQK RLANAAVIPV GSTLVKGSRL FIRLGENLAP
LMFEVPRVFG AYDTLFGYMG SKEAPEVSDY IQLLRDLKDE CCGHSLNLNE LVAAARAIDL
LVAAMAESNY RLSREEKNSI FLPSGTAVMQ SMLVMAFNDS ASLCSSVDLT ELHVVHPRIS
TRCCKMLEVP GITSIVTEEL DGGENPTELL ASDDIAHFNS VLASQQFADG LRKIITAQQQ
KASSYDAFGF IPDFEDLNQR IMNLAKYEVK CVAELHSRFI AKLGFPARRV DVTKTERQSS
LSFLDQTRRI IYITKRTLEA RSEKGMRVSH LVARCINQLL GGVLQDCSVL ESILTCDEME
IPDVLQQLDI YEDPVLIVEK LRGVLGQPLC DSDCANVELA PLRSCLPGEL IAVEDENGTL
CYGKILRGEP SDIPGVSRYD VKVSSSSTRW MLATQLHFFR SARVGTSGSS AGVQTGRMVE
NHTTNHLENV ALPASVVAIA PETQGSEIVP GFSSVNAPAA VVSTANVLSA VNDLLSRLNV
TLDTSVEDLM AENLRLQRHL EVAEAGRRAA AAQIDSVIRE KKEVQDSLVC AVCLENQVNR
VLIPCGHIYC ASCVQQLPRP SCPICRQNIV SSSAFHVPS
//
