ID W2S7S7_9EURO Unreviewed; 758 AA.
AC W2S7S7;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 24-JAN-2024, entry version 42.
DE RecName: Full=Cdc23 domain-containing protein {ECO:0000259|Pfam:PF04049};
GN ORFNames=HMPREF1541_10402 {ECO:0000313|EMBL:ETN44732.1};
OS Cyphellophora europaea CBS 101466.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Cyphellophoraceae; Cyphellophora.
OX NCBI_TaxID=1220924 {ECO:0000313|EMBL:ETN44732.1, ECO:0000313|Proteomes:UP000030752};
RN [1] {ECO:0000313|EMBL:ETN44732.1, ECO:0000313|Proteomes:UP000030752}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 101466 {ECO:0000313|EMBL:ETN44732.1,
RC ECO:0000313|Proteomes:UP000030752};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Phialophora europaea CBS 101466.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KB822714; ETN44732.1; -; Genomic_DNA.
DR RefSeq; XP_008713295.1; XM_008715073.1.
DR AlphaFoldDB; W2S7S7; -.
DR STRING; 1220924.W2S7S7; -.
DR GeneID; 19977741; -.
DR VEuPathDB; FungiDB:HMPREF1541_10402; -.
DR eggNOG; KOG1155; Eukaryota.
DR HOGENOM; CLU_018320_2_0_1; -.
DR InParanoid; W2S7S7; -.
DR OrthoDB; 3131281at2759; -.
DR Proteomes; UP000030752; Unassembled WGS sequence.
DR GO; GO:0005680; C:anaphase-promoting complex; IEA:InterPro.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR InterPro; IPR007192; APC8.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR12558; CELL DIVISION CYCLE 16,23,27; 1.
DR PANTHER; PTHR12558:SF10; CELL DIVISION CYCLE PROTEIN 23 HOMOLOG; 1.
DR Pfam; PF04049; ANAPC8; 1.
DR Pfam; PF13414; TPR_11; 1.
DR Pfam; PF13181; TPR_8; 2.
DR SMART; SM00028; TPR; 6.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50005; TPR; 3.
PE 4: Predicted;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW Reference proteome {ECO:0000313|Proteomes:UP000030752};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT DOMAIN 21..334
FT /note="Cdc23"
FT /evidence="ECO:0000259|Pfam:PF04049"
FT REPEAT 395..428
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 429..462
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 497..530
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 128..155
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 535..563
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 596..686
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 736..758
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 133..155
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 535..556
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 605..639
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 758 AA; 85087 MW; 9A2855C56E44F890 CRC64;
MVDARASFGV GVPTDPELIA ELRDRLTEAS IKCSERCLYQ SAKWAAELLN SLPEEADLDD
DSQMLNADAP QSSYRIFSTS YDDPIEAALE AREAPRYLLA KTFFDTKEFD RCAAVFIPPA
IPAGGLAIFE KPKGRNSTST PKSKTKAKQS EVPTNPFPKL SQKSLFLGLY AKYLAGEKRK
EEETEMVLGP ADGGQTVNKE LPALARGLEG YFRARDAIDP ELKRSQGWLE FLYGFILARL
KQESVAQQWL IRSVRLNPYH WGAWEELASL LSSVDDLNAH LASSILPQNI MIIFYQTHAN
VDLFSTTDAS ATINSLNTLL SIFPDSTFLL TQLALCHYHG KDFETSASVF QEILTSHPHR
LDALDHYSNI LYVMEDRPKL AFLAHLATSV DKFRPETCCV VGNYYSLCSQ HEKAVMYFRR
ALTLDRSFLS AWTLMGHEYI ELKNTHAAIE SYRRAVDVNR KDYRAWYGLG QAYEVLDMGF
YALFYYQRAA GLRPYDPKMW QAVGSCYSKM ERYDQAIKAL KRALVAGTYF ETSDATPQQS
FGASINSTAS TKQKQRPTGR KLLDPETLYS IAQMYERLQN EHEAARYMEL CMAQETGASS
RGVSEAEKAM RKRAKKEARR AELAAERKRL MRTPGQEEES MQTEDDDGGD GDTEILSSPS
SPSTDDEQDD ADREDGFGTG TTETTSKARL WLARHAYKLA DLEKAERLAE ELCMDGFEVE
EAKSLVREVR GRKDFTRPHL AQGQGPGSGA SDFGTPIA
//
