ID W2TLD1_NECAM Unreviewed; 213 AA.
AC W2TLD1;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=7TM GPCR serpentine receptor class x (Srx) domain-containing protein {ECO:0000259|Pfam:PF10328};
GN ORFNames=NECAME_07847 {ECO:0000313|EMBL:ETN82593.1};
OS Necator americanus (Human hookworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae; Bunostominae;
OC Necator.
OX NCBI_TaxID=51031 {ECO:0000313|EMBL:ETN82593.1, ECO:0000313|Proteomes:UP000053676};
RN [1] {ECO:0000313|Proteomes:UP000053676}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24441737; DOI=10.1038/ng.2875;
RA Tang Y.T., Gao X., Rosa B.A., Abubucker S., Hallsworth-Pepin K., Martin J.,
RA Tyagi R., Heizer E., Zhang X., Bhonagiri-Palsikar V., Minx P., Warren W.C.,
RA Wang Q., Zhan B., Hotez P.J., Sternberg P.W., Dougall A., Gaze S.T.,
RA Mulvenna J., Sotillo J., Ranganathan S., Rabelo E.M., Wilson R.K.,
RA Felgner P.L., Bethony J., Hawdon J.M., Gasser R.B., Loukas A., Mitreva M.;
RT "Genome of the human hookworm Necator americanus.";
RL Nat. Genet. 46:261-269(2014).
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DR EMBL; KI658412; ETN82593.1; -; Genomic_DNA.
DR RefSeq; XP_013304820.1; XM_013449366.1.
DR AlphaFoldDB; W2TLD1; -.
DR EnsemblMetazoa; NECAME_07847; NECAME_07847; NECAME_07847.
DR GeneID; 25347877; -.
DR KEGG; nai:NECAME_07847; -.
DR CTD; 25347877; -.
DR OMA; WEICHAF; -.
DR OrthoDB; 2874484at2759; -.
DR Proteomes; UP000053676; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR019430; 7TM_GPCR_serpentine_rcpt_Srx.
DR PANTHER; PTHR23017:SF3; G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR23017; SERPENTINE RECEPTOR, CLASS X; 1.
DR Pfam; PF10328; 7TM_GPCR_Srx; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053676};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 15..37
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 49..71
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 91..114
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 135..156
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 162..187
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 23..103
FT /note="7TM GPCR serpentine receptor class x (Srx)"
FT /evidence="ECO:0000259|Pfam:PF10328"
FT DOMAIN 108..179
FT /note="7TM GPCR serpentine receptor class x (Srx)"
FT /evidence="ECO:0000259|Pfam:PF10328"
SQ SEQUENCE 213 AA; 23912 MW; 3BDCF56CECD60DF3 CRC64;
MSNSTTAAYL SLENIAVSAI IAVVGIFGLL SNAAAMISVR CNPVLRSSFG VLCFSHSVAN
FGVMLVFVFW VTPMTVIHSD ISSELLGKIF GQINIMFWDI MNHQGSGSTV SLAAHKKRRQ
IETRFFMQTL YQNALFFYEI SNFYYVTVLF TDPWAVFFTS TFAWEICHAF DGFVVVLFNF
HLSFIGIHTT KTRSAMISEH KKTTSAWHIV TNG
//
