ID W2TM24_NECAM Unreviewed; 301 AA.
AC W2TM24;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Methyltransferase domain-containing protein {ECO:0000259|Pfam:PF13383};
GN ORFNames=NECAME_08186 {ECO:0000313|EMBL:ETN82087.1};
OS Necator americanus (Human hookworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae; Bunostominae;
OC Necator.
OX NCBI_TaxID=51031 {ECO:0000313|EMBL:ETN82087.1, ECO:0000313|Proteomes:UP000053676};
RN [1] {ECO:0000313|Proteomes:UP000053676}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24441737; DOI=10.1038/ng.2875;
RA Tang Y.T., Gao X., Rosa B.A., Abubucker S., Hallsworth-Pepin K., Martin J.,
RA Tyagi R., Heizer E., Zhang X., Bhonagiri-Palsikar V., Minx P., Warren W.C.,
RA Wang Q., Zhan B., Hotez P.J., Sternberg P.W., Dougall A., Gaze S.T.,
RA Mulvenna J., Sotillo J., Ranganathan S., Rabelo E.M., Wilson R.K.,
RA Felgner P.L., Bethony J., Hawdon J.M., Gasser R.B., Loukas A., Mitreva M.;
RT "Genome of the human hookworm Necator americanus.";
RL Nat. Genet. 46:261-269(2014).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KI658576; ETN82087.1; -; Genomic_DNA.
DR RefSeq; XP_013304314.1; XM_013448860.1.
DR AlphaFoldDB; W2TM24; -.
DR STRING; 51031.W2TM24; -.
DR EnsemblMetazoa; NECAME_08186; NECAME_08186; NECAME_08186.
DR GeneID; 25348216; -.
DR KEGG; nai:NECAME_08186; -.
DR CTD; 25348216; -.
DR OMA; YEVNGYS; -.
DR OrthoDB; 34467at2759; -.
DR Proteomes; UP000053676; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR InterPro; IPR025714; Methyltranfer_dom.
DR InterPro; IPR026913; METTL24.
DR PANTHER; PTHR32026; METHYLTRANSFERASE-LIKE PROTEIN 24; 1.
DR PANTHER; PTHR32026:SF10; METHYLTRANSFERASE-LIKE PROTEIN 24-RELATED; 1.
DR Pfam; PF13383; Methyltransf_22; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053676};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..23
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 88..276
FT /note="Methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF13383"
SQ SEQUENCE 301 AA; 34277 MW; 0AE7364869556B0F CRC64;
MTRKGVVLGA TLIIFAVIII LTYHGDKRLA AVDSVYTRLS NLTQMFGVAQ TANDSETTRS
WVREYYSRQA ADRIRALDTI TGSITNFASL YNTMVPEVYC PALVRVGTVL DGGKFVCNPH
DMPKNCSIYS LGLNNEISFD VDIQEFNNYT CRIYGYDRDI QAAEISIRYK EVNGEVESVT
ISPKTNVTKN EYFLGDLLIK NKDTYAEILK MDIEYAEHKT LIPFLQRFSV CQILLEIHGK
PIQHVTLLHQ IAELDYALFS YEVNGYSLEA CEYSFINLNC MARYGATIWK LYLKHVNPSE
M
//
