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Database: UniProt
Entry: W2TMA8_NECAM
LinkDB: W2TMA8_NECAM
Original site: W2TMA8_NECAM 
ID   W2TMA8_NECAM            Unreviewed;       206 AA.
AC   W2TMA8;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   27-SEP-2017, entry version 17.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETN82769.1};
GN   ORFNames=NECAME_07774 {ECO:0000313|EMBL:ETN82769.1};
OS   Necator americanus (Human hookworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Strongylida; Ancylostomatoidea; Ancylostomatidae; Bunostominae;
OC   Necator.
OX   NCBI_TaxID=51031 {ECO:0000313|EMBL:ETN82769.1, ECO:0000313|Proteomes:UP000053676};
RN   [1] {ECO:0000313|Proteomes:UP000053676}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=24441737; DOI=10.1038/ng.2875;
RA   Tang Y.T., Gao X., Rosa B.A., Abubucker S., Hallsworth-Pepin K.,
RA   Martin J., Tyagi R., Heizer E., Zhang X., Bhonagiri-Palsikar V.,
RA   Minx P., Warren W.C., Wang Q., Zhan B., Hotez P.J., Sternberg P.W.,
RA   Dougall A., Gaze S.T., Mulvenna J., Sotillo J., Ranganathan S.,
RA   Rabelo E.M., Wilson R.K., Felgner P.L., Bethony J., Hawdon J.M.,
RA   Gasser R.B., Loukas A., Mitreva M.;
RT   "Genome of the human hookworm Necator americanus.";
RL   Nat. Genet. 46:261-269(2014).
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DR   EMBL; KI658383; ETN82769.1; -; Genomic_DNA.
DR   RefSeq; XP_013304996.1; XM_013449542.1.
DR   GeneID; 25347804; -.
DR   KEGG; nai:NECAME_07774; -.
DR   CTD; 25347804; -.
DR   Proteomes; UP000053676; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:InterPro.
DR   InterPro; IPR019424; 7TM_GPCR_Srsx.
DR   InterPro; IPR000276; GPCR_Rhodpsn.
DR   InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR   Pfam; PF10320; 7TM_GPCR_Srsx; 1.
DR   SMART; SM01381; 7TM_GPCR_Srsx; 1.
DR   PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000053676};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053676};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM      6     31       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     43     63       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     83    108       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    120    145       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       25    115       G_PROTEIN_RECEP_F1_2.
FT                                {ECO:0000259|PROSITE:PS50262}.
SQ   SEQUENCE   206 AA;  22944 MW;  B65D777209D45B0E CRC64;
     MGISVSLLVL VSLITIAFNC AGLFGNFNII IALIRKPALR SKAGYLMGLL CCFQSFCLLF
     ELSNIRIYWS EMIMGKGVCF RVVYPHLFCM VAQSLMYFII TLDMLIAISA PLRHKMWPKV
     PYVIVMCAPP TMFASTAWIG SYFYIGEGSF YSCRLLTASI ISVGAAADVP PSSLSGRCFF
     WPVISLTMLN LSHCFHDSDC YDTSKL
//
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