ID W2TR82_NECAM Unreviewed; 239 AA.
AC W2TR82;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Ras family protein {ECO:0000313|EMBL:ETN84184.1};
DE Flags: Fragment;
GN ORFNames=NECAME_07005 {ECO:0000313|EMBL:ETN84184.1};
OS Necator americanus (Human hookworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae; Bunostominae;
OC Necator.
OX NCBI_TaxID=51031 {ECO:0000313|EMBL:ETN84184.1, ECO:0000313|Proteomes:UP000053676};
RN [1] {ECO:0000313|Proteomes:UP000053676}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24441737; DOI=10.1038/ng.2875;
RA Tang Y.T., Gao X., Rosa B.A., Abubucker S., Hallsworth-Pepin K., Martin J.,
RA Tyagi R., Heizer E., Zhang X., Bhonagiri-Palsikar V., Minx P., Warren W.C.,
RA Wang Q., Zhan B., Hotez P.J., Sternberg P.W., Dougall A., Gaze S.T.,
RA Mulvenna J., Sotillo J., Ranganathan S., Rabelo E.M., Wilson R.K.,
RA Felgner P.L., Bethony J., Hawdon J.M., Gasser R.B., Loukas A., Mitreva M.;
RT "Genome of the human hookworm Necator americanus.";
RL Nat. Genet. 46:261-269(2014).
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DR EMBL; KI658001; ETN84184.1; -; Genomic_DNA.
DR RefSeq; XP_013306411.1; XM_013450957.1.
DR AlphaFoldDB; W2TR82; -.
DR STRING; 51031.W2TR82; -.
DR EnsemblMetazoa; NECAME_07005; NECAME_07005; NECAME_07005.
DR GeneID; 25347036; -.
DR KEGG; nai:NECAME_07005; -.
DR CTD; 25347036; -.
DR OMA; DRFACEN; -.
DR OrthoDB; 8685at2759; -.
DR Proteomes; UP000053676; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR CDD; cd01869; Rab1_Ypt1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR001806; Small_GTPase.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR47977:SF26; LD21953P; 1.
DR PANTHER; PTHR47977; RAS-RELATED PROTEIN RAB; 1.
DR Pfam; PF00071; Ras; 1.
DR PRINTS; PR00449; RASTRNSFRMNG.
DR SMART; SM00177; ARF; 1.
DR SMART; SM00175; RAB; 1.
DR SMART; SM00176; RAN; 1.
DR SMART; SM00173; RAS; 1.
DR SMART; SM00174; RHO; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51417; ARF; 1.
DR PROSITE; PS51419; RAB; 1.
DR PROSITE; PS51421; RAS; 1.
DR PROSITE; PS51420; RHO; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000053676}.
FT REGION 217..239
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ETN84184.1"
SQ SEQUENCE 239 AA; 26586 MW; F3857FB09FA52129 CRC64;
QSNWPPKYPK VSRPLISVEE DGSDEPRIER RKVYKAPFFA CSDYLFKLLL IGDSGVGKSC
LLLRFADDTY TESYISTIGV DFKIRTIELD GKTIKLQIWD TAGQERFRTI TSSYYRGAHG
IIVVYDITDQ ESFNNVKQWL QEIDRYACEN VNKLLVGNKC DLTAKRAVET QAAKDYADQL
GIPFLETSAK SSTNVEQAFL TMASEIKSRM GPVQGAGGAP AVRITGSQPV QDKKSGGCC
//
