ID W2VGP8_9FIRM Unreviewed; 197 AA.
AC W2VGP8;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE RecName: Full=UDP-N-acetylglucosamine kinase {ECO:0000256|ARBA:ARBA00011963};
DE EC=2.7.1.176 {ECO:0000256|ARBA:ARBA00011963};
DE AltName: Full=UDP-N-acetylglucosamine kinase {ECO:0000256|ARBA:ARBA00032897};
GN ORFNames=HMPREF1495_2393 {ECO:0000313|EMBL:ETO97486.1};
OS Lachnoanaerobaculum sp. MSX33.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Lachnoanaerobaculum.
OX NCBI_TaxID=936596 {ECO:0000313|EMBL:ETO97486.1, ECO:0000313|Proteomes:UP000018910};
RN [1] {ECO:0000313|EMBL:ETO97486.1, ECO:0000313|Proteomes:UP000018910}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MSX33 {ECO:0000313|EMBL:ETO97486.1,
RC ECO:0000313|Proteomes:UP000018910};
RA Durkin A.S., Haft D.R., McCorrison J., Torralba M., Gillis M., Haft D.H.,
RA Methe B., Sutton G., Nelson K.E.;
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + UDP-N-acetyl-alpha-D-glucosamine = ADP + H(+) + UDP-N-
CC acetyl-alpha-D-glucosamine 3'-phosphate; Xref=Rhea:RHEA:32671,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:57705,
CC ChEBI:CHEBI:64353, ChEBI:CHEBI:456216; EC=2.7.1.176;
CC Evidence={ECO:0000256|ARBA:ARBA00000912};
CC -!- SIMILARITY: Belongs to the zeta toxin family.
CC {ECO:0000256|ARBA:ARBA00009104}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETO97486.1}.
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DR EMBL; AZXX01000060; ETO97486.1; -; Genomic_DNA.
DR RefSeq; WP_034212674.1; NZ_AZXX01000060.1.
DR AlphaFoldDB; W2VGP8; -.
DR PATRIC; fig|936596.3.peg.1023; -.
DR eggNOG; COG4185; Bacteria.
DR OrthoDB; 9791543at2; -.
DR Proteomes; UP000018910; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010488; Zeta_toxin_domain.
DR PANTHER; PTHR39206; SLL8004 PROTEIN; 1.
DR PANTHER; PTHR39206:SF1; SLL8004 PROTEIN; 1.
DR Pfam; PF06414; Zeta_toxin; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 2..164
FT /note="Zeta toxin"
FT /evidence="ECO:0000259|Pfam:PF06414"
SQ SEQUENCE 197 AA; 22424 MW; 6B8E02A2540B91E4 CRC64;
MPTYTIFAGV NGAGKSTLYS ILLQENHDFG VRVNSDEIVI SNSGDWRNKS DQAKAMKMAV
KIIKDCMNKC ISFNQETTLT GRSMLNNILK AKKLGYKIIM NYVGLNSPEL AIQRVAHRVS
MGGHGIPEED IKRRYYVSLS KLKELMSLID ELYIYDNSKH MKLVAKEIAG CRTLLENNCL
WLSSSHLFDR YTNEFML
//
