ID W2VPM8_9FIRM Unreviewed; 561 AA.
AC W2VPM8;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE SubName: Full=Beta-eliminating lyase {ECO:0000313|EMBL:ETO99383.1};
GN ORFNames=HMPREF1495_0354 {ECO:0000313|EMBL:ETO99383.1};
OS Lachnoanaerobaculum sp. MSX33.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Lachnoanaerobaculum.
OX NCBI_TaxID=936596 {ECO:0000313|EMBL:ETO99383.1, ECO:0000313|Proteomes:UP000018910};
RN [1] {ECO:0000313|EMBL:ETO99383.1, ECO:0000313|Proteomes:UP000018910}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MSX33 {ECO:0000313|EMBL:ETO99383.1,
RC ECO:0000313|Proteomes:UP000018910};
RA Durkin A.S., Haft D.R., McCorrison J., Torralba M., Gillis M., Haft D.H.,
RA Methe B., Sutton G., Nelson K.E.;
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- SIMILARITY: Belongs to the beta-eliminating lyase family.
CC {ECO:0000256|ARBA:ARBA00009721}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETO99383.1}.
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DR EMBL; AZXX01000002; ETO99383.1; -; Genomic_DNA.
DR RefSeq; WP_034211075.1; NZ_AZXX01000002.1.
DR AlphaFoldDB; W2VPM8; -.
DR PATRIC; fig|936596.3.peg.38; -.
DR eggNOG; COG3033; Bacteria.
DR OrthoDB; 9764079at2; -.
DR Proteomes; UP000018910; Unassembled WGS sequence.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR GO; GO:0006520; P:amino acid metabolic process; IEA:InterPro.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 2.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR001597; ArAA_b-elim_lyase/Thr_aldolase.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR PANTHER; PTHR32325; BETA-ELIMINATING LYASE-LIKE PROTEIN-RELATED; 1.
DR PANTHER; PTHR32325:SF4; TRYPTOPHANASE; 1.
DR Pfam; PF01212; Beta_elim_lyase; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000313|EMBL:ETO99383.1}.
FT DOMAIN 52..506
FT /note="Aromatic amino acid beta-eliminating lyase/threonine
FT aldolase"
FT /evidence="ECO:0000259|Pfam:PF01212"
SQ SEQUENCE 561 AA; 64184 MW; 6E4F31600AD5AB33 CRC64;
MEYEKMLGVE APKSWTHVVR EVPTVTQEQR KKALEMTHYN EFAFPAGLLY IDCLSDSGTT
SMTDTQWSAM FLADESYGRN KGYYVLLDAF RDVWERGDDQ KRLINYIKEG VDKDDVEKMM
NEVYLVDYEG GFINGGKYQL SRPNTFIVPQ GRCAEALLFD VLKPLFAKRW PGKVFTIPSN
AHFDTTEGNI KQMGNVPRNL FHKEILFEVP ESGKYEKNPF KGDMDIDKLN QLIEAVGVEN
VPLIYSTVTN NSVCGQAVSM KNIREVSKIA HKYNIPFVMD GARWAENCYF IKMNEEGYAD
KSICEIAKEM FSYFDVVSAS LKKNGHANMG GVLAFRDKGL FWQKFSEFNE DGSVKTDIGH
LLKVRQISAY GNDSYGGMSG HDIMALCQGM YEEARFDYQD ERVRQCQYLA DGLTANGVPV
VQPAGGHGIY IDVDKFFNYK RGHESFAGQA LSLEMIHRYG IRCSELGDFS MEYDLKTPEQ
QKEVCNVVRL AINRSQFSKQ HMDYIIAALT QLYKDRDTVP NLKITFGHTL PMRHFHAWAE
PYAPSKEEMC DEGNYGYWEK K
//
