ID W2W3W7_PHYPR Unreviewed; 1211 AA.
AC W2W3W7;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=FAD-binding FR-type domain-containing protein {ECO:0000259|PROSITE:PS51384};
GN ORFNames=F441_18605 {ECO:0000313|EMBL:ETP04688.1};
OS Phytophthora parasitica CJ01A1.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=1317063 {ECO:0000313|EMBL:ETP04688.1, ECO:0000313|Proteomes:UP000018958};
RN [1] {ECO:0000313|EMBL:ETP04688.1, ECO:0000313|Proteomes:UP000018958}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CJ01A1 {ECO:0000313|EMBL:ETP04688.1,
RC ECO:0000313|Proteomes:UP000018958};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Johnson C.S., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Phytophthora parasitica CJ01A1.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETP04688.1}.
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DR EMBL; ANIX01003733; ETP04688.1; -; Genomic_DNA.
DR AlphaFoldDB; W2W3W7; -.
DR EnsemblProtists; ETP04688; ETP04688; F441_18605.
DR Proteomes; UP000018958; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd07067; HP_PGM_like; 1.
DR CDD; cd06186; NOX_Duox_like_FAD_NADP; 1.
DR Gene3D; 3.40.50.80; Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module; 1.
DR Gene3D; 3.40.50.1240; Phosphoglycerate mutase-like; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR InterPro; IPR000778; Cyt_b245_heavy_chain.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR013112; FAD-bd_8.
DR InterPro; IPR017927; FAD-bd_FR_type.
DR InterPro; IPR013130; Fe3_Rdtase_TM_dom.
DR InterPro; IPR013121; Fe_red_NAD-bd_6.
DR InterPro; IPR039261; FNR_nucleotide-bd.
DR InterPro; IPR013078; His_Pase_superF_clade-1.
DR InterPro; IPR029033; His_PPase_superfam.
DR InterPro; IPR017938; Riboflavin_synthase-like_b-brl.
DR PANTHER; PTHR11972:SF69; METALLOREDUCTASE AIM14-RELATED; 1.
DR PANTHER; PTHR11972; NADPH OXIDASE; 1.
DR Pfam; PF08022; FAD_binding_8; 1.
DR Pfam; PF01794; Ferric_reduct; 1.
DR Pfam; PF00300; His_Phos_1; 1.
DR Pfam; PF08030; NAD_binding_6; 1.
DR PRINTS; PR00466; GP91PHOX.
DR SFLD; SFLDS00052; Ferric_Reductase_Domain; 1.
DR SFLD; SFLDG01168; Ferric_reductase_subgroup_(FRE; 1.
DR SFLD; SFLDG01169; NADPH_oxidase_subgroup_(NOX); 1.
DR SMART; SM00855; PGAM; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF52343; Ferredoxin reductase-like, C-terminal NADP-linked domain; 1.
DR SUPFAM; SSF53254; Phosphoglycerate mutase-like; 1.
DR SUPFAM; SSF63380; Riboflavin synthase domain-like; 1.
DR PROSITE; PS51384; FAD_FR; 1.
PE 4: Predicted;
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW NADP {ECO:0000256|ARBA:ARBA00022857};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 673..689
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 754..777
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 808..828
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 840..861
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 873..1010
FT /note="FAD-binding FR-type"
FT /evidence="ECO:0000259|PROSITE:PS51384"
FT REGION 398..428
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 414..428
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1211 AA; 137253 MW; DDD0C310B060D214 CRC64;
MTGPHSTSSS NSPTIRAVDG FFSTIPQAEA SSELLQLFRQ FKLATSSWSE FREKLEADGT
RNLKVVFFIR HGEGLHNEAI KLYGSERWYK ELVTSDVYRD AELTPFGIQD AKNKGPPSIK
AEMERGMPPI ERVVVSPISR AIQTAQNFFV ENQIPDKPFV CIESCREHLG VDTCNNRRSV
SELKAKFPAV DFSALKDEED TLWTTDYRES AEEIQTRAKE FLTELFRTIP ERHVAVVTHF
GFIEAVCAAM LGMKIEAVLS RQHGRLDITL STSVKCRVQN VSGSLVDFAP SDDILLSGLE
TKMVVNYASN EPQPGDSIFP RSTTTTPAST IKSEFAMLET NTPVECTHTL HQEETKELQR
LPSALAMPRI YGPSVRQPPI DSQSKRTSFV AMLGGSGVDR HVRKPLGNSR RGHTRRAGGT
TNRSSFLPNE SALNMSFHPS MSGASMWSRP SRQMNKAELY ELKDRLWKDS LSSAPSNAFG
AVDCGDPHAP EQLSFFTHAF NTSRITGEGS AALGYDERSR SSMAFIPLPR ESVAMMIDAV
RVSALDDNEK CRFLFEMFDV EHHGVLTKEG VRAFIEATFA ANGVDFVGAF DYDAVVDKVF
GHCRQPYKMT FNEFKAIFAD VVVEADDDKS KEALGLMSSV VETQRQREIV YNNEQGGRWY
RVKKYCRKYK PEIFWLTLYF LLMIGVFIAK ASRFPVDPAV GNCPRIAKGF AEICLVNTMF
VLLPMCRNFV TGLRTLPVVV NHLPIDNHIE FHKVCGVVML IASVGHTAAW LAIVIYVRTV
PLAVWEASRY HHLSFVRDEN LFDFALRIPI WTGMVMLICA GIAAPLCLAK YRRGNFNMFW
VTHMLFIPFL VLMAFHGFAR WLAEPQAQYW ILPPVVIFLI EKRYRMTQVF GGQTKIIHVQ
LSKESVAIFM KKPRSFGKRQ RFLPGMYMFI NVPAISKFEW HPFTISSAPE DKFLSLHIQK
AGDWTGALYK NLEMLQREHK ASSIEDQGSP MTSPYPVVYL DGPVGAPAQD YSRYREVVLI
GAGIGVTPFA SILRSIMHQW ESFRCPHCRH VRFPPSFQLR KIYFYWVTRE QESLTWFTNT
MNQLSEMDTE NRLEIHNFFS SVKSEAVIAP LQALQKFIHN NEGQDIISGL NTKQQTHFGR
PDWNTELSRV ARNHRLLEPS VNTSDEREEI GVFFCGPKPL GNIIHEQCTV LNQAKARQAP
DVQFEFHSEN F
//
