ID W2WII7_PHYPR Unreviewed; 1720 AA.
AC W2WII7;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=Nephrocystin-3 {ECO:0000256|ARBA:ARBA00040387};
DE Flags: Fragment;
GN ORFNames=F441_13978 {ECO:0000313|EMBL:ETP10385.1};
OS Phytophthora parasitica CJ01A1.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=1317063 {ECO:0000313|EMBL:ETP10385.1, ECO:0000313|Proteomes:UP000018958};
RN [1] {ECO:0000313|EMBL:ETP10385.1, ECO:0000313|Proteomes:UP000018958}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CJ01A1 {ECO:0000313|EMBL:ETP10385.1,
RC ECO:0000313|Proteomes:UP000018958};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Johnson C.S., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Phytophthora parasitica CJ01A1.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETP10385.1}.
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DR EMBL; ANIX01002771; ETP10385.1; -; Genomic_DNA.
DR EnsemblProtists; ETP10385; ETP10385; F441_13978.
DR Proteomes; UP000018958; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR Gene3D; 3.30.1370.10; K Homology domain, type 1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR024983; CHAT_dom.
DR InterPro; IPR036612; KH_dom_type_1_sf.
DR InterPro; IPR007111; NACHT_NTPase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR45641:SF1; NEPHROCYSTIN-3; 1.
DR PANTHER; PTHR45641; TETRATRICOPEPTIDE REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_6G03870); 1.
DR Pfam; PF12770; CHAT; 1.
DR Pfam; PF05729; NACHT; 1.
DR Pfam; PF00536; SAM_1; 1.
DR Pfam; PF13374; TPR_10; 2.
DR Pfam; PF13424; TPR_12; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM00454; SAM; 1.
DR SMART; SM00028; TPR; 3.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 1.
DR PROSITE; PS50005; TPR; 1.
PE 4: Predicted;
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}; Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687}.
FT DOMAIN 4..68
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT REPEAT 1426..1459
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 919..992
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1220..1306
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1503..1523
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1660..1720
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 919..950
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 967..992
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1228..1245
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1255..1303
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1508..1523
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1702..1720
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ETP10385.1"
SQ SEQUENCE 1720 AA; 189132 MW; 066691EC7858408A CRC64;
WSSWSCADVG QWLCAQGFQE HVELFAANKI SGAILPELTR NALRDDLGIA AFGDRVRISQ
AIEALIASSS AGESTPSPTS ISATTTSTMT TSQQLNQAWL PRDDYALDLV VLHAAPLVIK
DSRHRIYPME KLDLEAERRE ISNSLLTDVQ HKAIHVRFDI ATADILRSLM TAWKCTVLHF
SGHGLGQRAA LCFEDGVGCT HLITPDALRQ LMFSGDRRQQ QVPGAAPVEM KTVDSGITGP
KPLDGNVQLV FVNACHSQKV ASVFLNAGIP HVVAVHSDSL VVDASATMFA KHFYLSLFHG
HTVSTAFEIA KGAVRALPTQ KRAACCCAHL HEPTCTWMRD GSRHSQHSAT QCCCKGHVLA
FPHDESSKFL LLGTAPHDVV LFGDIPNGKL RDYTPRYPSN IPSMHGQFIG RNTETYLMVK
SLRENAVTAC LGAPGIGKSS LIISVAHFVH SRRMFPDGVF YVDLEGQKLS TVRYAIAQSI
GMPAADTDEE VFAELGTKNC LLVLDKVEEL LDEDENKGEE LLHQLISVAP NLKLLLASRR
NMHIPSVTPY SLSISELPLH TATELLCLVA PGCSTSLAER LARICGCLPL AIRVVGRALA
NARMTVTPER MIEYLERDEH RFETIRELNQ VGHKECVDRC IRSSFCHLDE PLRLAFMAFG
FFRGSFEIEA AEAVLSSVLT EQNAAGKLAG GSGYSLTSSS LSGSGGTTTS ASSTTYFPAE
AYAKSNRSRN RDDDASSVRS LGSQLSNMDG FGFDNDGAMT NDSYDLLDLE SSEEVNAREV
IVPSASVALE LLHQWSLVEF DSKTNRYRMH NLVQLFAEEE AGRMGDECFA DPASTSSPNS
APSSFVTASM GAPPTSIPLG KELLLTWKRR FVRYYCMIVA KASHAYRFDG TLALFDKERA
NIESAMRLAH ELTQQSIEQV RESNRRTQQD LVSGQLDEAP ASSASAMRSK SEPSFFMDDG
TTPKPSMERH SRSFAGNTSN SSNSSSGVGF GRRSTGAATL NNSSIVDALL YSNLVVRCRF
IFRARVEPRR RIQVVSSCLQ LSRETRSLNC TCGNRENDPA TLLWDVEEAK FDRELSLLDK
LPSFEEPQLP AAAAAAHDRC TCVGIRELIA LEALLLTDLG YACCDVTDWV AAEYHYLESL
RLQREVLGWS EHPQVAEVLN QFGICLSTRW GYLAHNVWLL QHAERLLKGA LQMRSRVLSK
NHPEYATSLN NLANFYKNYP TAGKRRSPSA AQREEARDSR NRHMRGGKNS GRRGGGARSG
SSPSPSRSNT SSESLKSASQ DSATNHAEAP GKSTTSSNAE GEPQPDIASM YRQSLKIREI
TLGENHPQVA QSLNNLALYL SNQLETQQLS EEELATQRAE IGRLYERALR IRRSRLGNAS
FETAATLNNM GNFKRLAKDW RGAEENIKEA LQITDRYFND ISPRAARIFI NLARVYRDQK
LYEEAIAAYK KAQDIRQQLF PDTRDVGFCI EQIGKCLRLQ GMEEEGKAVE ERGRQMKKLG
LSALEQDEMG QDESSSSMSG ETNSFKHAVL SGDSVESSVS SGHLFAKVNV YDSVDAEALV
SRKFNFPGKL LGERGIHLKK IEAIACAQLR YFGPWPQTLS KWGKGRGDGK KEISQQSMPE
AYIQITSTSE AALERAKEQS VLLLREMKLS WERFLARTAA HQGGAGHRGQ PPPLHHQHGR
GGGASRGGGR GRHLHLHRTP ISAQLPRSSS AAGGAWGSIT
//
