ID W2WTW1_PHYPR Unreviewed; 2204 AA.
AC W2WTW1;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 08-NOV-2023, entry version 38.
DE RecName: Full=Bromodomain and WD repeat-containing protein 1 {ECO:0008006|Google:ProtNLM};
GN ORFNames=F441_11081 {ECO:0000313|EMBL:ETP13951.1};
OS Phytophthora parasitica CJ01A1.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=1317063 {ECO:0000313|EMBL:ETP13951.1, ECO:0000313|Proteomes:UP000018958};
RN [1] {ECO:0000313|EMBL:ETP13951.1, ECO:0000313|Proteomes:UP000018958}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CJ01A1 {ECO:0000313|EMBL:ETP13951.1,
RC ECO:0000313|Proteomes:UP000018958};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Johnson C.S., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Phytophthora parasitica CJ01A1.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETP13951.1}.
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DR EMBL; ANIX01002202; ETP13951.1; -; Genomic_DNA.
DR EnsemblProtists; ETP13951; ETP13951; F441_11081.
DR Proteomes; UP000018958; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd04369; Bromodomain; 1.
DR CDD; cd15571; ePHD; 1.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 1.20.920.10; Bromodomain-like; 2.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR001487; Bromodomain.
DR InterPro; IPR036427; Bromodomain-like_sf.
DR InterPro; IPR034732; EPHD.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR16266:SF17; BRWD3; 1.
DR PANTHER; PTHR16266; WD REPEAT DOMAIN 9; 1.
DR Pfam; PF00439; Bromodomain; 2.
DR Pfam; PF00400; WD40; 5.
DR Pfam; PF13771; zf-HC5HC2H; 1.
DR PRINTS; PR00503; BROMODOMAIN.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00297; BROMO; 2.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF47370; Bromodomain; 2.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50014; BROMODOMAIN_2; 2.
DR PROSITE; PS51805; EPHD; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 3.
DR PROSITE; PS50082; WD_REPEATS_2; 6.
DR PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE 4: Predicted;
KW Bromodomain {ECO:0000256|PROSITE-ProRule:PRU00035};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT REPEAT 360..391
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 392..433
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 434..460
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 515..542
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 694..727
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 823..865
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 1268..1381
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS51805"
FT DOMAIN 1708..1778
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT DOMAIN 2022..2090
FT /note="Bromo"
FT /evidence="ECO:0000259|PROSITE:PS50014"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 40..80
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 551..577
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 628..650
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1055..1219
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1865..1896
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1952..1980
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2114..2204
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 59..80
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 630..646
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1068..1106
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1107..1131
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1156..1190
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1201..1219
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1878..1896
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1955..1973
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2120..2138
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2155..2178
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2188..2204
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2204 AA; 247080 MW; C420D3CDF821FFC1 CRC64;
MADDPAPLSP ERNTDAQLAA ADDDTLAAIW LGDDVPRARE ELPAIAAPQV SESDGPAVVQ
TVEEHKSDEP ADSEQERVPP PVDESEVYFL IADFLKRRSV CLKAADVLIQ ELAEHQLLKG
GVDWTGKPRA AAYEDYRLRH RDISSSHLVQ LLQGASASFP RLNGKKEVDD KVKDAPIEEN
RSLLLKARVK TQLQLSVEER KKLAKEIVNQ LLKVRAVLKT LRVVEKVIRK YERYHKYMTA
SRVEELPPEL QLMLTGDRKT DAGTDKVTTL AADVRALKQL FQLRQERAEV EKQVEMLMQR
AKQSGLFQTT ARTGRNQASL LRRREIRWQH DTQLPPAYVY SRIRRLKTLS GHLQIQAYCL
AYDKLGKVVI TGSDDRLVKI WSLRTGDLLF TLRGHVGNIT DLAVNHSNTL LASSSDDKTV
RVWEISTGAP VAVLVGHSSV VNAVRFHPKK NIIVTASDDG RCFCYKVPEI PLMDQPETKI
ETARRLYSLN AYMLSLHPIY SMKHARREGV RSCKVHCVTF SRCGDFVASG GHDGIARVWD
LSMVSAPDAP AVVPRYQPTD EPQEARAPEQ QLGGNGPQIP PVTVPVIPAP VAQALNPALG
NLQTPLVQQT MSQVDGVAAS VIGEPFRAVA PPQPLDPAPL QPQTGPDVPL PTVAEALQRE
TAPRPTQPPQ VQNDLPSLSL SDDAVPSIEP IALLKGHKGP VSSIAYNHRG DRIVTASIKD
STARVWKWKR KYKSLFGAVL LAKESSAEYD EISAMYGVRG RKKPTPVVDM VAWTHDDKRL
ITLHSVKLNS ESADPTWEQR IRIWDPESGK LLMTLGAIDK EKKNGHVNAA FALSTHPTDW
RIVVTAGYDG RVFLWDISSG RMLKSFTNLS PDSKPLSNLD GGFTPDGSGF CFTDQIGRLL
IFGTGTGEQY AATPVQQYFL HDYVMLVTDG HYNVRDRETQ ELPSLMDSGP LMDASLVQYP
HQPPHLLPDK LFTSEEYAEN RRLRIQQSKE SEIQCGVHHL PEAEEDIQSF PLAIVKSEEK
KSSQGQTSFA ADAMALARAS YRLNGAPVML SELRRRGSGS RRYADHRRRR ERPAEERDTS
VLELEISSED DRSDEDFQVP TPRHAAEEEE DEEDEDEEEL DLDEDDLLSD NEEAVIYPAN
SRRRRLRSTP ARGGRRLQSE SEEEQEDAPR QLRTRRNAAR RSRLVLDSDA EEEGEIPGDE
QSDAGGEREA RNRDDSAEVV VESNDGVIMG DNQRDRFDDS MSYTQMLEAK RAQLGAAPIP
AENTDDALIP CAFCGVGNDD GMLKLPGDGM GVHPLIFGVQ RVFVHDQCAI ASPLCFNRDG
NWYNVTREIR RGRSLSCVAC TKRGATIGCT ISACRNSYHW KCAINLGWSV DQMHFFCPAH
QSRPLQRNRH EETRQSAAED GGAIIEPASK RFGLKFHREW LQLVSLRSIH QYVPQVGDYV
VYLPEGHPGY LHYGGMPHPR YYERLSKFYA VKCRVVDIKY VFPTAEEHAR CSIIKCELLL
AVLAVPTSAV RSSGENEEQK QEEETKEDVA DTAGLFNPES SPFAEFTSVD EALTPAASEP
STRFNFKVLY HSNDVANFLV LDHIYESGVC GNWRVGDRVQ MPYVQLNDHG LEEEAKMSYG
TVDSILRKPF ATSNSGEITP WECVKINWDA PDDEICAVCP WELEAASPEE RREKRVLSLR
RRSTRLFFSR YIIGEKCEAL LQEMDQVLTL SISRDFMYPV DEDTFMDYST MVANPIDLTK
IQQRLRLGYY RQVEAFLADV KLLSVNCETY NIPSSAISQN SRNLVSAVLT QAQRHFPHLL
NRREADGERA SMSYSYPPDD FLTNFSEDPE ETQLALLEVE LLIPTSVDTS SNASAVAGQV
DAAPAVAAPA SSDVQETSPL RRSRRHTRSN ETADNVAAEE KVDHVVEEQI ETTVNTAPSQ
AQSTSNGVDT AVFNSPRQLL KREVPEPQLL SPRTRRATRV VTTPSTNNGG SARKRQRRSA
DQELLTYSAL MDKYSVKNRE LIERACKEDL RSVLMIFHEA LTETDKEDIF AAPVTDDFAP
RYSEIIPRPM DFGTINDKLY KYRSFRDYFA HVELVFSNAI TYNGWHSFIG GLVEDLQKYC
VKFLLDAAGA NLRGMKNPST KKAARSTDKT STSKLPGKQR ARQKPAAVSE DEEDSWSSSS
SESEEDDDEE EDESLTDESD YDVGRKRRLR RPAPKSKKKA KRRY
//
