ID W2XIE1_PHYPR Unreviewed; 590 AA.
AC W2XIE1;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Acid phosphatase {ECO:0008006|Google:ProtNLM};
GN ORFNames=F441_04259 {ECO:0000313|EMBL:ETP22421.1};
OS Phytophthora parasitica CJ01A1.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=1317063 {ECO:0000313|EMBL:ETP22421.1, ECO:0000313|Proteomes:UP000018958};
RN [1] {ECO:0000313|EMBL:ETP22421.1, ECO:0000313|Proteomes:UP000018958}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CJ01A1 {ECO:0000313|EMBL:ETP22421.1,
RC ECO:0000313|Proteomes:UP000018958};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Johnson C.S., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Phytophthora parasitica CJ01A1.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a phosphate monoester + H2O = an alcohol + phosphate;
CC Xref=Rhea:RHEA:15017, ChEBI:CHEBI:15377, ChEBI:CHEBI:30879,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:67140; EC=3.1.3.2;
CC Evidence={ECO:0000256|ARBA:ARBA00000032};
CC -!- SIMILARITY: Belongs to the histidine acid phosphatase family.
CC {ECO:0000256|ARBA:ARBA00005375}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETP22421.1}.
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DR EMBL; ANIX01000949; ETP22421.1; -; Genomic_DNA.
DR AlphaFoldDB; W2XIE1; -.
DR EnsemblProtists; ETP22421; ETP22421; F441_04259.
DR Proteomes; UP000018958; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1240; Phosphoglycerate mutase-like; 1.
DR InterPro; IPR033379; Acid_Pase_AS.
DR InterPro; IPR000560; His_Pase_clade-2.
DR InterPro; IPR029033; His_PPase_superfam.
DR PANTHER; PTHR11567:SF110; ACID PHOSPHATASE 1, ISOFORM B; 1.
DR PANTHER; PTHR11567; ACID PHOSPHATASE-RELATED; 1.
DR Pfam; PF00328; His_Phos_2; 1.
DR SUPFAM; SSF53254; Phosphoglycerate mutase-like; 1.
DR PROSITE; PS00616; HIS_ACID_PHOSPHAT_1; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 21..590
FT /note="Acid phosphatase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004829855"
FT TRANSMEM 549..571
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 590 AA; 65556 MW; 40ADFFB272F22D76 CRC64;
MKLGRAATLL ALGTLSLVNA AMYAPDSGLR QVIVLSRHGV RGPYGLGTES PSEDLLKQYV
LNPNLNLPLS ANAWGTSETE DPAEIVSPKL TKHGFHVVKQ MGAYFRDHLY EEFLNAACEE
TFAYADNNQR DNLTALAFLS GLYPLCTELV PITKETQSLF EQGQDPTANC PVCSRAVYEG
ITGSNDTRFV LQEIQEEVAE VNELLQCCAA SVCSTDEEPE KSDSTESATC DLFGIPTQWN
GAFYLPWKDT LSNADYFSEW LLLQSLNNMS LPSQLSFEKI LSLARIHETH MDLITNEVNS
ANFGATLLAH LTASFEQNIM QKPLPVAKGE GPHLLQGPEN RLLYYAAHDI NLLYVRNLLR
LQWHTKGWHP HQPVPGGMLV FELHATPTKS NKQTSPTTSE FRNLKSTGRV SWDVEVAVDT
EDASRFYVKL YFVAASPEQI RNGDELSSEN PPDRVQVIIP SCSEEIDIGD GATDVRCPFS
TFKKLIGKTL KHVCVADTLR PFVDSLIHEK ITNHSTLTTA IKVDQVRSIG IGSADTGKSL
PKTTAVFEAL LWTVFGVLIL CFMVLLVRHI FNRHPERQKY GSIPMQINNR
//
