ID W2Y4G1_PHYPR Unreviewed; 1387 AA.
AC W2Y4G1;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 13-SEP-2023, entry version 33.
DE RecName: Full=FYVE-type domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=F442_21247 {ECO:0000313|EMBL:ETP29612.1};
OS Phytophthora parasitica P10297.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=1317064 {ECO:0000313|EMBL:ETP29612.1, ECO:0000313|Proteomes:UP000018948};
RN [1] {ECO:0000313|EMBL:ETP29612.1, ECO:0000313|Proteomes:UP000018948}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P10297 {ECO:0000313|EMBL:ETP29612.1,
RC ECO:0000313|Proteomes:UP000018948};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Johnson C.S., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Phytophthora parasitica P10297.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETP29612.1}.
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DR EMBL; ANIY01004404; ETP29612.1; -; Genomic_DNA.
DR EnsemblProtists; ETP29612; ETP29612; F442_21247.
DR Proteomes; UP000018948; Unassembled WGS sequence.
DR GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.530.20; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR023393; START-like_dom_sf.
DR InterPro; IPR002913; START_lipid-bd_dom.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13510; FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED; 1.
DR PANTHER; PTHR13510:SF44; RABENOSYN-5; 1.
DR Pfam; PF01363; FYVE; 1.
DR SMART; SM00064; FYVE; 1.
DR SUPFAM; SSF55961; Bet v1-like; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS50848; START; 1.
DR PROSITE; PS50178; ZF_FYVE; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000018948};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT DOMAIN 74..262
FT /note="START"
FT /evidence="ECO:0000259|PROSITE:PS50848"
FT DOMAIN 294..362
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 394..546
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 695..833
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 979..1016
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1118..1172
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1224..1251
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10..25
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 394..423
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 802..816
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 979..999
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1133..1153
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1387 AA; 152467 MW; 28E8E8E14D088688 CRC64;
MARGLSSSRV AGPAASTSSN ESLGSSRVWT PLRENYFEPP LLSSRERAYL VRKSCEAAQE
LVERARSAGG PIAWRHVEKN NGVQIYAGSP RSTATGAALT AASMCGVTSV PGTVKEVASL
FQLGSTRQMK EFARAHREWF YDGVVLHTLA PRTKEKPLHQ VTAKWMVVQM PHGLPHRDFC
YLECQDKFID ARGRKGWVLG QHSIKLPGCD DLKREFGLVR GSLYHSGFVV VESEERPGHV
DVIHLVQLNL KEHTPVPASL LRMRVLFVAQ VRNMLRSKRL NEQRYLSDLE LVPRKYRARC
AVCQDSFSLL LLRKLNCRKC GEVVCAACSK EFPIENRNFA ATNGGDEVRK LRICMHCFQV
ITNAPKPTSA LVEPPHSSTM SMSFLGYHDD ERRASRVGHH GRREEEAPKI FLQSMRREKP
SSRRMSSTSP IPGFGADLPP STSRHRSRGQ PDADLYRRSQ RYQQQQQDYS RSRDHRGSQL
MRPSDFRPSQ SLSLDDPIAR GEGRYTLQMP GPPPVPSPAS IFDRPATGAS RRPQNGIPRS
QSSDMLLGAG TGGRNMSNFS RLQELSSRER LEQLQRQDNY MSRSSIDHRM PDAYMSALQQ
ASRDKHDFDA PPMYQAPPSD FGAYGATLDD HAVIPDFGTY DSTLDDPNAP PPLDMSALTT
SASTIPIELN SMSMAAMPPT APRDGGRGHE LLRQREREME QRRSSTSSDS SASSIDIDTY
DDTPGRAVVP PIAEQKHDES IGRMTPKTQV QNPVDSIENG LKAAKIYDTD EDSETSMGAS
DDEEERRVST KLSTFSNALP RKPIDDDAEE TKAHEFAETP ALPPPSPSAH TATRQVLERP
SIANSSVGSQ LAPRFTNNTH AVEVVAPKNT EVVEDLIDHD QQLQRSKVED LIDHEYQKES
ITTLDERVSK KSHDDGGVDV VTRKYTLHGR YDQAEKTKHE QLSESEDEAI LNTVGCDMNY
LDADMRQFHD QSLFIRQSRD GTSSQLKDGV SSYERMPTSP KTESGKALDL AKPSRPSISR
EETFVLDNMS VEEQQRSANT RVVLGSSELS SPSTTRTDDR FATDVSLVSA PVDGTADDLA
FDGAQRDSEV PRASLANLVE DEHTTPPVIP VSMMLSADPE QTSGDEVSES RSRASSRISF
SSVPSSSARG SSICSMGLDA ITPPATPPSS SPVAIERLSA TSASSPAAVP ALDLAATNPS
IGNEAALQPR SNSNAPAYLP DRFRTEQQSS AKEPSGSSTP RQSNDSNSTL DNFQLNFSAS
FNAHQEQKSQ ASGVLEGISR LAQDERNRAS SSSSTGSSDV QVFRYQSVGS SVLDTVPASG
VSEDEDSEDE SMLLSARKLY GRFGNTKQLS KLGGDRPGFQ QTLTQIQQSF DELSSDSEDD
EKKPAAP
//
