ID W2YCM7_PHYPR Unreviewed; 2358 AA.
AC W2YCM7;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=EF-hand domain-containing protein {ECO:0000259|PROSITE:PS50222};
GN ORFNames=F442_18894 {ECO:0000313|EMBL:ETP32383.1};
OS Phytophthora parasitica P10297.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=1317064 {ECO:0000313|EMBL:ETP32383.1, ECO:0000313|Proteomes:UP000018948};
RN [1] {ECO:0000313|EMBL:ETP32383.1, ECO:0000313|Proteomes:UP000018948}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P10297 {ECO:0000313|EMBL:ETP32383.1,
RC ECO:0000313|Proteomes:UP000018948};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Johnson C.S., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Phytophthora parasitica P10297.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the WD repeat EMAP family.
CC {ECO:0000256|ARBA:ARBA00006489}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETP32383.1}.
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DR EMBL; ANIY01003981; ETP32383.1; -; Genomic_DNA.
DR EnsemblProtists; ETP32383; ETP32383; F442_18894.
DR Proteomes; UP000018948; Unassembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 6.
DR InterPro; IPR024977; Apc4-like_WD40_dom.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR005108; HELP.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR13720:SF33; HELP DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR13720; WD-40 REPEAT PROTEIN; 1.
DR Pfam; PF12894; ANAPC4_WD40; 1.
DR Pfam; PF03451; HELP; 3.
DR Pfam; PF00400; WD40; 11.
DR SMART; SM00320; WD40; 27.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 4.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 7.
DR PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Reference proteome {ECO:0000313|Proteomes:UP000018948};
KW WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT DOMAIN 152..187
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REPEAT 579..609
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 933..966
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1271..1310
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 1623..1657
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 2068..2099
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 2172..2206
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 2323..2358
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 1669..1695
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2358 AA; 258076 MW; 03146ECF0E6AAF1C CRC64;
MLKRERLRSS VGVIVMGNAL LLAAVKDRQA VALADAILPF DNLRLHEIEA FWRAFYDSAT
SFALSKAQLR SICCRAVASG VSSLHSSSVR VAEYADSAFD LFTESLMQRR WQQVQPGVRG
LQSQQYQNPS DSLTAIDALE FLSAIAFIAA IPLDEKIDLL FDSWDMSEDG ALDLDEFTIS
LKSTLSGLAK IIQPASCSRT TTSDATVDEE EIVMLAESTF RDISNCGASS SKETRSEESP
TITCEQFREF CMKNKRAKEL FDLFDVADEM RGINHEEEGM PLELVAKLEK HSDPTESSAT
VDTPMDAMQD DVGDMFLAVK PWIGAIVAPT KIPPLSKGAP LVSVELDWIF GYSAQDCKNN
VRFAATTANA KSGRFEEIVY PAAAVSVVLN TKTMKQRHHL SHTDDILSLC LHPRLPLAAS
GEIGKQPKII VWNLETMDDQ CVIQGFHKRG ILQLAFLSPD MLVSIGGDDD HSIAIYESSN
NWKSAVLRIS VKGNKAAPFH ITTNPRVPSE FVTCGQKYIE FWSLGGKELV SKKGLLGKKG
SLQPFPVAQY LETADQAVVV GTSDGCLYLF VGRQLTNVIK AHEGAITVLF YSSGVLLSGG
RDGQIIQWDD KLKQVGSPIQ IRDSLESSLL PQRKGIRSCC YSPDRRTILV GTLASEIYEL
DAKTGQNVHS EPLTKGHFQG ELWGLDTHPT KQQCCTVGDD QTLRVWDLAE KYELGFLELP
IPGRACTYSG DGKLIAVGLG TEDSGKTGKP AVNAKKQQPN GGFVVYSGVD LTCVKEPCFD
AKRWVSDVKF SPDNRTLAVA SHDSKIYLYN VLKGFSRTHV FNKHSSYITH MDFSLDGNYL
QSTSGGYELL FTEVKTGKHV TNASTFRDEV WHTITSTLGW SVQGIWEAES DGTDVNAVDR
SNNGKLLATG DDFGKVKVFQ YPCALEKASF LELRGHASHV TNVRWSPDDN YIVSVGGNDR
CVFVWKHDKQ PVQKDYFQRR LSETDSDSEE IEHLDKRADD PLEVAATNDD VGDEFMAVRP
WLGAVVAPSK AASMKVDSTS PNTRLELERV HGYQAQTASN NARYDSNGKV VYHTAALGIV
FDKSAQRQSF FRSHDDDVVA LCAHPNGTTF ATSQMGKKPK IYVWDSASGE AVAPCLEGFH
QRFVNAICFS SDGTKLGSVG GDDDHSIAIY NWQSGVLSSQ SRGERNNVRG ICYHAASKEW
VTCGDKHIRF WTEQGKNLTS KKAIFGTKAH QSGKVPSVFD CVVSFGQMVV AGGSTGHLVV
FQNSVDVTKT VQAHDTAVLA LYATERELIS GGKDSKIAVW DAQFSKMAAF DMKEYTLQGA
KLLNSEIRSI CSSKISPRLF LVGTGGSDLI EFDAGRAQPT LSTISRGHYR VEVWGLACHP
TKAEYCTVGD DQTIRVWCLV KKIQLRIQRL ECVARACALS DAADVVAIGF GGRNAITGLS
KTAQAKTGGI VLLCYSDLTK KVFEDRPSKQ AISEMKFSPN GSVLAVGSHD HKVYLYRLDR
NATKVVKAAV FDKHQSYITH LDFSADSQVL QSNCGAYELL FSNASTGKHI TSASSTKDTQ
WHSWTCVLGW PVQGIWPPCS DGTDVNAVAR NSRENLLVTS DDFGLVKLYC YPCVAKNASS
VDHRGHSSHV TNVRWSCDDS YVVSVGGNDR SIMEWRVLNE GEQISAVPGS DKRLSLIEPE
ETTDSSAESE DEPFDDAAGD EFMAVKPWIG AIVAPTNAAT PNSREPDLNV ELEWVFGYQS
ELSQQNLVYN AQDEIVYHTA AVGIIYDSTN HFQRHHVGHN DDIISLAICD DKRNLIATGE
RGKKPALRVW DAHTGELRCE MKEFHSRGIL SLAFSSDSTR LVSVGDDDDH SLAVWSDASN
GSWTLAKLLA TGKGDKAVNR FASFGANADT IITGGVKHVL FWSVQGKTLV SKKGIVGKKG
TLQTFPTGCN FGGDFVTGTA GGELYVWRGN DLSRAVKAHD GDVRVVASMR STDNSAGSSA
VVLSGGKDGR VVMWNAAYQS LKCFDLGAMQ VGSFGKFINS VYLNSTGRKL LVGTCSSDII
EIDVASGSVL NGGQPLFSGH FAMELWGLAV HPSQREFVTV GDDRTLRVWD MEAKRLIQAR
LLPAKARACA YSPDSELLAV GFGGDNGVRQ RRKPASKQGQ AQSREGGFAV LRARDLDTGT
LVFEDKPAKE WISDVKFSPN GDILALGSHD NSIYLYSVGS GASEFKKRKP FSKHNSYITH
FDFSDDGKYI QSNCGAYEYL FCDTASSSQV SRASSVRDVH WATWTCTLGW PVQGIWPDCA
DGTDINAVCA SSTRTILASG DDSGNVKFFR YPCIPKGSKF IARRGHSSHV ANVRFSFDDK
YLISVGGNDR SIFQWKLA
//
