ID   W2Z2Z7_PHYPR            Unreviewed;       636 AA.
AC   W2Z2Z7;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   13-SEP-2023, entry version 35.
DE   RecName: Full=FYVE-type domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=F442_11227 {ECO:0000313|EMBL:ETP41727.1};
OS   Phytophthora parasitica P10297.
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Phytophthora.
OX   NCBI_TaxID=1317064 {ECO:0000313|EMBL:ETP41727.1, ECO:0000313|Proteomes:UP000018948};
RN   [1] {ECO:0000313|EMBL:ETP41727.1, ECO:0000313|Proteomes:UP000018948}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=P10297 {ECO:0000313|EMBL:ETP41727.1,
RC   ECO:0000313|Proteomes:UP000018948};
RG   The Broad Institute Genomics Platform;
RA   Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA   Machado M., Johnson C.S., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Phytophthora parasitica P10297.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ETP41727.1}.
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DR   EMBL; ANIY01002326; ETP41727.1; -; Genomic_DNA.
DR   AlphaFoldDB; W2Z2Z7; -.
DR   EnsemblProtists; ETP41727; ETP41727; F442_11227.
DR   Proteomes; UP000018948; Unassembled WGS sequence.
DR   GO; GO:0008289; F:lipid binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd00065; FYVE_like_SF; 1.
DR   Gene3D; 3.30.530.20; -; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR023393; START-like_dom_sf.
DR   InterPro; IPR002913; START_lipid-bd_dom.
DR   InterPro; IPR000306; Znf_FYVE.
DR   InterPro; IPR017455; Znf_FYVE-rel.
DR   InterPro; IPR011011; Znf_FYVE_PHD.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PANTHER; PTHR13510; FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED; 1.
DR   PANTHER; PTHR13510:SF44; RABENOSYN-5; 1.
DR   Pfam; PF01363; FYVE; 1.
DR   Pfam; PF01852; START; 1.
DR   SMART; SM00064; FYVE; 1.
DR   SUPFAM; SSF55961; Bet v1-like; 1.
DR   SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR   PROSITE; PS50848; START; 1.
DR   PROSITE; PS50178; ZF_FYVE; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018948};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00091}.
FT   DOMAIN          19..245
FT                   /note="START"
FT                   /evidence="ECO:0000259|PROSITE:PS50848"
FT   DOMAIN          272..332
FT                   /note="FYVE-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50178"
FT   REGION          375..469
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          507..593
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        378..404
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        416..469
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   636 AA;  69735 MW;  B084526D1B40AA52 CRC64;
     MSTSLPLPKG FFNTNVRVSE DMRRQYIEFA EASIRKVFAL SDCHKNSWIP MREKKGVAIY
     RNFGQMHGPK AYKSNVAEVG CKGQLSASLD QVGRAYAAHD DALFRRLMKK LNPAVMDAAV
     LLTVVPRTPL TPFRYIGIKW YAVKTPTPIV SHRDYCCLEV QDKIVDSFGN EMYIRVLNSI
     EVNECPSLEN SHGLVRAKIL AGYMYRIDRA ESNVVRVHHV ARFDPGGYFP AQWAFKTAES
     QLVNSIVQIR RVIDKQQMNS CTFVDKRQWV PNHERLHCAV CSRTFGTFRP RHHCRSCGEV
     ICGKCSVFKS VEVPGTTLKN VRICSVCNMG VQKTGGQDDD GNMSDISTSS VTSSSTIAHN
     EMNLMDLYMG NGGGPRTPSA YSDASAQSNL SIRSTTSTRS AYDARGRAHS QARGSRNPGA
     FFNESNTPRS YIANNLTPRS TLGFGFGSGA STPRSGANSA ATTPSGGVRP SISAASVVAA
     AAITAQRLSS YKLNPVDIGY LRDSVNETSA SEARERPEDP TTSWPPAKMQ RLETEETADV
     DMESDDQEEM EAKPAAPLAS DVQEAQQRPP AMQLPTVERI SESPFEQSSR ASTVLRVSLD
     KEDPSGAPAS GLRPFFSGIL SRVRGESVEK SSHRAA
//