ID   W2ZPY4_PHYPR            Unreviewed;      1008 AA.
AC   W2ZPY4;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   27-MAR-2024, entry version 41.
DE   RecName: Full=Vacuolar protein sorting-associated protein 11 homolog {ECO:0000256|PIRNR:PIRNR007860};
GN   ORFNames=F442_05104 {ECO:0000313|EMBL:ETP49348.1};
OS   Phytophthora parasitica P10297.
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Phytophthora.
OX   NCBI_TaxID=1317064 {ECO:0000313|EMBL:ETP49348.1, ECO:0000313|Proteomes:UP000018948};
RN   [1] {ECO:0000313|EMBL:ETP49348.1, ECO:0000313|Proteomes:UP000018948}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=P10297 {ECO:0000313|EMBL:ETP49348.1,
RC   ECO:0000313|Proteomes:UP000018948};
RG   The Broad Institute Genomics Platform;
RA   Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA   Machado M., Johnson C.S., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Phytophthora parasitica P10297.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the VPS11 family.
CC       {ECO:0000256|ARBA:ARBA00007070, ECO:0000256|PIRNR:PIRNR007860}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ETP49348.1}.
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DR   EMBL; ANIY01001105; ETP49348.1; -; Genomic_DNA.
DR   AlphaFoldDB; W2ZPY4; -.
DR   EnsemblProtists; ETP49348; ETP49348; F442_05104.
DR   Proteomes; UP000018948; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:UniProtKB-UniRule.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   CDD; cd16688; RING-H2_Vps11; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   InterPro; IPR000547; Clathrin_H-chain/VPS_repeat.
DR   InterPro; IPR016528; VPS11.
DR   InterPro; IPR024763; VPS11_C.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   InterPro; IPR001841; Znf_RING.
DR   PANTHER; PTHR23323; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN; 1.
DR   PANTHER; PTHR23323:SF24; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 11 HOMOLOG; 1.
DR   Pfam; PF12451; VPS11_C; 1.
DR   PIRSF; PIRSF007860; VPS11; 4.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
DR   PROSITE; PS50236; CHCR; 2.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR007860};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018948};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00175}.
FT   DOMAIN          906..942
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50089"
FT   COILED          863..897
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   1008 AA;  114143 MW;  DAE560032034A477 CRC64;
     MAQWRRFAFF DKEVLKDANG PWMKGVDITS MSANRGLICV GDADGFVHLA NRSLEARKFQ
     AHELFVSHVV MMKRSNVLVT IGDGIDPRPD ELREQSKAIA EAGRSPNAEE MYTSKPSGKS
     TAVVRFWRTD QQDREGKPKL LQQIPVFAKK YPEEAVTAFA VNDDLSQFAV GLKNGAVILF
     RSDLKRRADR PPHLLQPAGQ YPVTGLSFTS KPVTATVSHV FLYASTRRGL TCYHCSHDDP
     ALVKSAGGAA ALPPRTTVLD ERGVDMNCSC VNEEGEIAVG QTDAVYFYTT EDRSVCFGFE
     GEKKYLCFFK HYLLVAHVDP RGRHQVNVYD LQNKFIAFNW TLTSTNPKGP MRKPPLASNA
     RAPGARFGLD EMEEVRHVVC EFGAIFVVSS MGHVYRLSEK DTTSKLEILF RKNLYSIAIS
     LAFSSNYDVN SIIDIFRMYG DHLYQKGDYD GSLRQYVRTI GHVEPSYVIR RFLDAQRIHN
     LTAYLEALHE KAFANAEHTT LLLNCYTKLK DVKKLDKFIQ LDEVIDAKKT KSDSDSGDLT
     PRNGAAANLN FDVETAISVL WENYPQHALT LAKKHEEHSW YLKIQLDHIS YVDSEDSAAL
     SESEKERVAD ALEYIEHLSF SEADSNLRKY GRTLVTHMPA PTTELLKRLC TGKFVPGNPS
     LKSDPGDFLH LFVSHRAQLK EFLQYIVEVE TVSNTSIGNT LLEMVLSDDD EEEGGTRSVE
     EKEEAVLRIL DNPRVKYDED HALIHLQMHG MKKGKRYLYN KLHMYHMLVQ FHIEENDDQS
     ILEEVRKHGE KDPNLWSLAL KYFAERGPLP KGATGGEEWK ELKQLLALID TNPAIPPLQV
     VQVLSQSREL PVSVIKQYVV NQLASDEKKI EEDEEKIKAF KGDTKQMKEE IAQLSSRAVV
     FQATKCDLCN HDLDLPAVHF MCQHSFHLNC ISETDRECIT CSMDHRHILG LKTQLEQKAG
     NHEQFYNQLE TAADGFHTIA EYFGKGIFKS NEVVLDEGSF ETRFSAEF
//