ID   W2ZQX7_PHYPR            Unreviewed;       541 AA.
AC   W2ZQX7;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   13-SEP-2023, entry version 26.
DE   RecName: Full=Glycosyl hydrolase family 30 TIM-barrel domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=F442_05059 {ECO:0000313|EMBL:ETP49406.1};
OS   Phytophthora parasitica P10297.
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Phytophthora.
OX   NCBI_TaxID=1317064 {ECO:0000313|EMBL:ETP49406.1, ECO:0000313|Proteomes:UP000018948};
RN   [1] {ECO:0000313|EMBL:ETP49406.1, ECO:0000313|Proteomes:UP000018948}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=P10297 {ECO:0000313|EMBL:ETP49406.1,
RC   ECO:0000313|Proteomes:UP000018948};
RG   The Broad Institute Genomics Platform;
RA   Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA   Machado M., Johnson C.S., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Phytophthora parasitica P10297.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 30 family.
CC       {ECO:0000256|ARBA:ARBA00005382}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ETP49406.1}.
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DR   EMBL; ANIY01001102; ETP49406.1; -; Genomic_DNA.
DR   AlphaFoldDB; W2ZQX7; -.
DR   EnsemblProtists; ETP49406; ETP49406; F442_05059.
DR   Proteomes; UP000018948; Unassembled WGS sequence.
DR   GO; GO:0004348; F:glucosylceramidase activity; IEA:InterPro.
DR   GO; GO:0006665; P:sphingolipid metabolic process; IEA:InterPro.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR   InterPro; IPR033452; GH30_C.
DR   InterPro; IPR001139; Glyco_hydro_30.
DR   InterPro; IPR033453; Glyco_hydro_30_TIM-barrel.
DR   InterPro; IPR013780; Glyco_hydro_b.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR11069; GLUCOSYLCERAMIDASE; 1.
DR   PANTHER; PTHR11069:SF23; LYSOSOMAL ACID GLUCOSYLCERAMIDASE; 1.
DR   Pfam; PF02055; Glyco_hydro_30; 1.
DR   Pfam; PF17189; Glyco_hydro_30C; 1.
DR   PRINTS; PR00843; GLHYDRLASE30.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF51011; Glycosyl hydrolase domain; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018948};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           23..541
FT                   /note="Glycosyl hydrolase family 30 TIM-barrel domain-
FT                   containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004832318"
FT   DOMAIN          103..464
FT                   /note="Glycosyl hydrolase family 30 TIM-barrel"
FT                   /evidence="ECO:0000259|Pfam:PF02055"
FT   DOMAIN          467..530
FT                   /note="Glycosyl hydrolase family 30 beta sandwich"
FT                   /evidence="ECO:0000259|Pfam:PF17189"
SQ   SEQUENCE   541 AA;  60325 MW;  3921F7E700880A1D CRC64;
     MLAPYLLTTL AGLLLATQEA SATCSNWSTR YQTNLEGVCV CNATQCDTVS NNYTSLTTGQ
     VGVYTTSKAG DRFAYKVANV DSTTVSSPTY SIDVSTQYQT MIGFGGAFTD AAAINVYKLS
     SKLQQMVLDQ YFSDTGLQYT LGRVPIGSTD FSTSIYSYND VVDDFEMEHF SINVDKSSSS
     HKIELIQRAL NTTSRDIKLF ASSWAPPVWM TTENTTINCA LKGNPGEEYW EALALYYSKF
     FDAYSEEGID FWAMTVQNEP SSSILQTSEW QSLRLTADQE RDFVKLDLGP RMAKDHPDLK
     IIAGDDQKSG ILDRLAPFED ADALKYISGL GVHWYRDLDF FFFSLGGDFD KLLSFYEDYP
     DIFMLATEAC EGYLPSWLGT GSGVSLTDAD KSWSRAENYG HDIIEDLNNY VAGWTDWNLA
     LDTTGGPNWA ENYVDAPILV DEENGVEFYK QPMFYIMGHF SKFVPAGSKR IEFPKTKTLS
     SFHRCAFVTP DNRVVIQFMN RDSSAVTVSV KQTDSKTFTL SLPAHSMQTV ILPASDDTTI
     L
//