ID   W2ZZI3_PHYPR            Unreviewed;       281 AA.
AC   W2ZZI3;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   22-FEB-2023, entry version 20.
DE   RecName: Full=Peptidase A2 domain-containing protein {ECO:0000259|PROSITE:PS50175};
GN   ORFNames=F442_02559 {ECO:0000313|EMBL:ETP52430.1};
OS   Phytophthora parasitica P10297.
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Phytophthora.
OX   NCBI_TaxID=1317064 {ECO:0000313|EMBL:ETP52430.1, ECO:0000313|Proteomes:UP000018948};
RN   [1] {ECO:0000313|EMBL:ETP52430.1, ECO:0000313|Proteomes:UP000018948}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=P10297 {ECO:0000313|EMBL:ETP52430.1,
RC   ECO:0000313|Proteomes:UP000018948};
RG   The Broad Institute Genomics Platform;
RA   Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA   Machado M., Johnson C.S., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Phytophthora parasitica P10297.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ETP52430.1}.
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DR   EMBL; ANIY01000553; ETP52430.1; -; Genomic_DNA.
DR   AlphaFoldDB; W2ZZI3; -.
DR   EnsemblProtists; ETP52430; ETP52430; F442_02559.
DR   Proteomes; UP000018948; Unassembled WGS sequence.
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   CDD; cd00303; retropepsin_like; 1.
DR   Gene3D; 2.40.70.10; Acid Proteases; 1.
DR   InterPro; IPR001995; Peptidase_A2_cat.
DR   InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR   Pfam; PF13650; Asp_protease_2; 1.
DR   SUPFAM; SSF50630; Acid proteases; 1.
DR   PROSITE; PS50175; ASP_PROT_RETROV; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018948}.
FT   DOMAIN          37..76
FT                   /note="Peptidase A2"
FT                   /evidence="ECO:0000259|PROSITE:PS50175"
SQ   SEQUENCE   281 AA;  32304 MW;  95AE63B8B58167C4 CRC64;
     MMKLNPGERQ GWWSAKKFDR RIRMRALVQG AVNDHRTRIL LDTGANVSVV TDTFAKKLRL
     RDIPGHGRSI GIQGISEGKV STTRRALVKI TLGWEMVYEF EMWVMAHSAG VDVVLGTDFM
     IPAGIRLDLF HGAAQLPNKV CIPLIKSKNM VDSMEYSAHV NAGPSEALNI PGHESREYRL
     AKRAARLEQR VRWVRRTEKV IPSVTRFRRG RPVRVRLTNV SERTAYVPAF DRLVMLVPVG
     DLPRGEGYVR LDSKKYKDWQ VLAYEICRDR QLFRRECELY E
//