ID   W3ALK4_9FIRM            Unreviewed;       260 AA.
AC   W3ALK4;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Putative divalent heavy-metal cations transporter {ECO:0000313|EMBL:ETP71885.1};
GN   ORFNames=UYO_2114 {ECO:0000313|EMBL:ETP71885.1};
OS   Lachnospiraceae bacterium JC7.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=1165092 {ECO:0000313|EMBL:ETP71885.1, ECO:0000313|Proteomes:UP000018967};
RN   [1] {ECO:0000313|EMBL:ETP71885.1, ECO:0000313|Proteomes:UP000018967}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JC7 {ECO:0000313|EMBL:ETP71885.1,
RC   ECO:0000313|Proteomes:UP000018967};
RA   Rosewarne C.P., Cheung J.L., Evans P.N., Tomkins N.W., Denman S.E.,
RA   O Cuiv P., Morrison M.;
RT   "Isolation and genomic characterisation of Lachnospiraceae sp. JC7, a newly
RT   identified member of the bovine rumen core microbiota.";
RL   Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ETP71885.1}.
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DR   EMBL; ALYD01000026; ETP71885.1; -; Genomic_DNA.
DR   AlphaFoldDB; W3ALK4; -.
DR   PATRIC; fig|1165092.3.peg.2092; -.
DR   OrthoDB; 9787346at2; -.
DR   Proteomes; UP000018967; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR003689; ZIP.
DR   PANTHER; PTHR11040:SF205; ZINC-REGULATED TRANSPORTER 3; 1.
DR   PANTHER; PTHR11040; ZINC/IRON TRANSPORTER; 1.
DR   Pfam; PF02535; Zip; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..25
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        37..58
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        70..91
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        181..205
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        241..259
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   260 AA;  27052 MW;  5BD7C83069CB9181 CRC64;
     MNMNVLIGIM IPFLGTALGS AGVFFMKKEL DNGIRRALTG FAAGVMVAAS IWSLIIPAMD
     QSEAMGRLSF LPAFVGFWLG ILFLLFLDCV IPHLHMNAEK AEGPHVSLRK TTMLVLAVTL
     HNIPEGMAVG VVFAGLVAGS ASITAGGALA LALGIAIQNF PEGAIISMPL CAEGNSKGKA
     FFYGVLSGAV EPVGAALTIL AAGFIVPAMP YLLSFAAGAM MYVVVEELIP EMSEGEHSNI
     GVIMFSVGFT LMMALDVALG
//