ID   W3AM50_9FIRM            Unreviewed;       431 AA.
AC   W3AM50;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   24-JAN-2024, entry version 33.
DE   SubName: Full=Bacterial capsule synthesis protein {ECO:0000313|EMBL:ETP72100.1};
GN   ORFNames=UYO_1890 {ECO:0000313|EMBL:ETP72100.1};
OS   Lachnospiraceae bacterium JC7.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=1165092 {ECO:0000313|EMBL:ETP72100.1, ECO:0000313|Proteomes:UP000018967};
RN   [1] {ECO:0000313|EMBL:ETP72100.1, ECO:0000313|Proteomes:UP000018967}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JC7 {ECO:0000313|EMBL:ETP72100.1,
RC   ECO:0000313|Proteomes:UP000018967};
RA   Rosewarne C.P., Cheung J.L., Evans P.N., Tomkins N.W., Denman S.E.,
RA   O Cuiv P., Morrison M.;
RT   "Isolation and genomic characterisation of Lachnospiraceae sp. JC7, a newly
RT   identified member of the bovine rumen core microbiota.";
RL   Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the CapA family.
CC       {ECO:0000256|ARBA:ARBA00005662}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ETP72100.1}.
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DR   EMBL; ALYD01000021; ETP72100.1; -; Genomic_DNA.
DR   AlphaFoldDB; W3AM50; -.
DR   PATRIC; fig|1165092.3.peg.1874; -.
DR   OrthoDB; 9810906at2; -.
DR   Proteomes; UP000018967; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
DR   CDD; cd07381; MPP_CapA; 1.
DR   Gene3D; 3.60.21.10; -; 1.
DR   InterPro; IPR019079; Capsule_synth_CapA.
DR   InterPro; IPR029052; Metallo-depent_PP-like.
DR   PANTHER; PTHR33393:SF12; LIPOPROTEIN-RELATED; 1.
DR   PANTHER; PTHR33393; POLYGLUTAMINE SYNTHESIS ACCESSORY PROTEIN RV0574C-RELATED; 1.
DR   Pfam; PF09587; PGA_cap; 1.
DR   SMART; SM00854; PGA_cap; 1.
DR   SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        20..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          96..346
FT                   /note="Capsule synthesis protein CapA"
FT                   /evidence="ECO:0000259|SMART:SM00854"
FT   REGION          49..90
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        64..90
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   431 AA;  47899 MW;  3589663E660F1A27 CRC64;
     MKKEIKDASS EIRMRNWRNM VIVVFFCIDL IMFALPAYSR VAARGWEPST KGPGIGMQTE
     DGTGMETAPV SETSAAEASE PAGSEVSSSD ESCKLTMIAA GDNLIHKTIV DKAWRPYQGT
     HDFHFLYTPI LDTIQSRDLS VINQETIFIS DNSLISDYPT FGTPQVMGEA LVDSGFDVVL
     SATNHTWDKG VRGVNDTLNY WKTFHPEITL LGIHDSPQAF NTIDYVEKNG IRLAMFNYTY
     GLNGFRVPSS LYYMVNLLSQ SDKFLNDVRI AENEADMTVC FLHIGEEYRY QPTAFQMGYV
     QALIDAGADL IICSHPHVVE PAGYITTALG NSGLVFWSCG NLISAQSKVP RILGGLADVT
     IIKDDSGTRI SSWDFIPTVT HFSGMDVRVF LLKDYNDILA SVNHANYKDG PLTTERLWNL
     WTSITGLGRK F
//