ID W3AV69_9FIRM Unreviewed; 859 AA.
AC W3AV69;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=ATPase with chaperone activity, ATP-binding subunit {ECO:0000313|EMBL:ETP73907.1};
GN ORFNames=UYO_0163 {ECO:0000313|EMBL:ETP73907.1};
OS Lachnospiraceae bacterium JC7.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=1165092 {ECO:0000313|EMBL:ETP73907.1, ECO:0000313|Proteomes:UP000018967};
RN [1] {ECO:0000313|EMBL:ETP73907.1, ECO:0000313|Proteomes:UP000018967}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JC7 {ECO:0000313|EMBL:ETP73907.1,
RC ECO:0000313|Proteomes:UP000018967};
RA Rosewarne C.P., Cheung J.L., Evans P.N., Tomkins N.W., Denman S.E.,
RA O Cuiv P., Morrison M.;
RT "Isolation and genomic characterisation of Lachnospiraceae sp. JC7, a newly
RT identified member of the bovine rumen core microbiota.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ClpA/ClpB family.
CC {ECO:0000256|RuleBase:RU004432}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETP73907.1}.
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DR EMBL; ALYD01000001; ETP73907.1; -; Genomic_DNA.
DR AlphaFoldDB; W3AV69; -.
DR PATRIC; fig|1165092.3.peg.163; -.
DR OrthoDB; 9803641at2; -.
DR Proteomes; UP000018967; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR CDD; cd19499; RecA-like_ClpB_Hsp104-like; 1.
DR Gene3D; 1.10.8.60; -; 2.
DR Gene3D; 1.10.1780.10; Clp, N-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 4.10.860.10; UVR domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR019489; Clp_ATPase_C.
DR InterPro; IPR036628; Clp_N_dom_sf.
DR InterPro; IPR004176; Clp_R_dom.
DR InterPro; IPR001270; ClpA/B.
DR InterPro; IPR018368; ClpA/B_CS1.
DR InterPro; IPR028299; ClpA/B_CS2.
DR InterPro; IPR041546; ClpA/ClpB_AAA_lid.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11638; ATP-DEPENDENT CLP PROTEASE; 1.
DR PANTHER; PTHR11638:SF193; CHAPERONE PROTEIN CLPB; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF07724; AAA_2; 1.
DR Pfam; PF17871; AAA_lid_9; 1.
DR Pfam; PF02861; Clp_N; 2.
DR Pfam; PF10431; ClpB_D2-small; 1.
DR PRINTS; PR00300; CLPPROTEASEA.
DR SMART; SM00382; AAA; 2.
DR SMART; SM01086; ClpB_D2-small; 1.
DR SUPFAM; SSF81923; Double Clp-N motif; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51903; CLP_R; 1.
DR PROSITE; PS00870; CLPAB_1; 1.
DR PROSITE; PS00871; CLPAB_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004432};
KW Chaperone {ECO:0000256|ARBA:ARBA00023186, ECO:0000256|RuleBase:RU004432};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004432};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|PROSITE-
KW ProRule:PRU01251}.
FT DOMAIN 1..144
FT /note="Clp R"
FT /evidence="ECO:0000259|PROSITE:PS51903"
FT REGION 813..859
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 417..467
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 813..830
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 839..859
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 859 AA; 96086 MW; EC251C970C0B2215 CRC64;
MNQFTIQAQR SLQLAIEAAE ELGHNYIGTE HILLGLRREG TAVAAKVLQS NGIDDERIKE
MIAKFISPDN SVAITDRAGY TPSAKKIMEN SMQEAMRSGS RLVGTEHILI SLLKDTNCVA
SRIIATLGGN AQRMYQQIMA VIGDDIIVDD RSSRQAQPAK QSETPTLDQY SRDLTEMAAN
GKLDPVIGRE SEIMRVIQIL SRRTKNNPCL IGEPGVGKTA VVEGLAERIF TGDVPETIQN
KRLVTLDISG MVAGSKYRGE FEERIKRVIA EARNDGNVLL FIDEIHTIIG AGGAEGALDA
ANILKPALAR GELQIIGATT LDEYRKHIEK DAALERRFQP VTVDEPSEDE TYDILKGIAP
KYEEHHHVVI DDEALKAAVS LSVRYINDRY LPDKAIDLVD EAASKIRINS SGEPQSIKKL
RAQIEALEAD KEQCIRKEDF EGASEIKKKQ EQKKQKLDKE FEKWQKDKEE NMLHVTETDI
ANVVSEWTKI PVQKLTEGET EKLMRLEDTL HKRVVGQTEA VSAVSKAIKR GRVGLKDPKR
PIGSFMFLGP TGVGKTELSK ALAEAMFGSE NNLIRVDMSE YMEKYSVSKM IGSPPGYVGY
DEGGQLSEKV RRNPYSVILF DEIEKAHPDV LNILLQVLDD GHITDAQGRK VSFKNTIIIM
TSNAGAEQIV SPKRLGFDTG DGSAEKDYQF MQSRVMDEVH RIFKPEFLNR IDEIIVFHQI
TRDNMKDILD IMMRDVINRA STQMNIRINL DAKSKEWIIE KGFNPKFGAR PLRRTIQTEV
EDKLAEEILD GKIPENSTVK ITVDKEENVL KFTDRSKPEA AAEKKPVKKA AAAPKKTSTR
RKKTTEPVQE ADTETLETK
//
