ID W4AG92_9BACL Unreviewed; 632 AA.
AC W4AG92;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Integral membrane sensor signal transduction histidine kinase {ECO:0000313|EMBL:ETT30495.1};
GN ORFNames=C162_32969 {ECO:0000313|EMBL:ETT30495.1};
OS Paenibacillus sp. FSL R7-269.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=1226755 {ECO:0000313|EMBL:ETT30495.1, ECO:0000313|Proteomes:UP000019056};
RN [1] {ECO:0000313|EMBL:ETT30495.1, ECO:0000313|Proteomes:UP000019056}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FSL R7-269 {ECO:0000313|EMBL:ETT30495.1,
RC ECO:0000313|Proteomes:UP000019056};
RX PubMed=24422886; DOI=10.1186/1471-2164-15-26;
RA Moreno Switt A.I., Andrus A.D., Ranieri M.L., Orsi R.H., Ivy R.,
RA den Bakker H.C., Martin N.H., Wiedmann M., Boor K.J.;
RT "Genomic comparison of sporeforming bacilli isolated from milk.";
RL BMC Genomics 15:26-26(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETT30495.1}.
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DR EMBL; ASPS01000144; ETT30495.1; -; Genomic_DNA.
DR RefSeq; WP_036702115.1; NZ_ASPS01000144.1.
DR AlphaFoldDB; W4AG92; -.
DR PATRIC; fig|1226755.4.peg.6503; -.
DR OrthoDB; 9776552at2; -.
DR Proteomes; UP000019056; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR010559; Sig_transdc_His_kin_internal.
DR PANTHER; PTHR34220; SENSOR HISTIDINE KINASE YPDA; 1.
DR PANTHER; PTHR34220:SF7; SENSOR HISTIDINE KINASE YPDA; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF06580; His_kinase; 1.
DR SMART; SM00304; HAMP; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:ETT30495.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 25..45
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 321..345
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 342..394
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
SQ SEQUENCE 632 AA; 72307 MW; DEC578D754381A9F CRC64;
MKERTGALWH SFHYWWGRRS LQSRLIAAYI FIILGPSLLV SFYSYQEINN TYMRDSIEKN
SYLLQMERMH VLNQIEAMER ALQMAYNDKS VRDYLISEDD PTLGELIDFN TTTFLNFSQI
QFNNPNIEHL YLFSASPNVY ELWPVIFRES RVSMEPWFQQ AMRLEGRRNL WSFQNTDIDL
MQRFSGGAGE GQPKVSVLRE ISIPAGNHIG MVQVDMLLSK FTPKTYTSVQ DNESQMVIVD
DALNLFTRTD NSFLTTDSGL SAAIKERLAA YRKTGEWEMD YKENGNSFLL IQAPVEQIDA
SLVTVVSMKG LMKDISRTRN LIIGVNIGFI FLVTAITYVL NAFILKNLRR LTETMKKVRR
GEPYGSIKVS GGGEVGELAH HFSKLMNTIN TLVAQAVYKQ ALSKEAELRT LHNQIDAHFL
YNTLENIKML AEIENQRTIS DALTRLGGMM RYNFKWTGEY VKLRDELRHI ENYIEVMNIR
FEHTIQLELH IDSAYLEVEV LKMSLQPIVE NSVKHAWNAD GVELTDRIVK IELTEAEGDI
FIVLRDNGLG LTQERLVELH EAIYAKEELG ADASGISSGG YKAGGVGLRN VHQRLQLFYG
EAYGLEVQSE AGKWTAVYMS LPKVLLTGDN QR
//
