ID W4IW43_PLAFP Unreviewed; 2750 AA.
AC W4IW43;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=MMS19 N-terminal domain-containing protein {ECO:0000259|Pfam:PF14500};
GN ORFNames=PFUGPA_04608 {ECO:0000313|EMBL:ETW53592.1};
OS Plasmodium falciparum (isolate Palo Alto / Uganda).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=57270 {ECO:0000313|EMBL:ETW53592.1, ECO:0000313|Proteomes:UP000019103};
RN [1] {ECO:0000313|EMBL:ETW53592.1, ECO:0000313|Proteomes:UP000019103}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Palo Alto/Uganda {ECO:0000313|EMBL:ETW53592.1,
RC ECO:0000313|Proteomes:UP000019103};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Hoffman S., Volkman S., Rosenthal P., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W.,
RA Alvarado L., Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J.,
RA Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A.,
RA Ireland A., Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W.,
RA Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Annotation of Plasmodium falciparum Palo Alto/Uganda.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ETW53592.1, ECO:0000313|Proteomes:UP000019103}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Palo Alto/Uganda {ECO:0000313|EMBL:ETW53592.1,
RC ECO:0000313|Proteomes:UP000019103};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Cheeseman I., Volkman S., Adams J., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Plasmodium falciparum Palo Alto/Uganda.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KI927385; ETW53592.1; -; Genomic_DNA.
DR EnsemblProtists; ETW53592; ETW53592; PFUGPA_04608.
DR OMA; KIEDWHC; -.
DR Proteomes; UP000019103; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR InterPro; IPR029240; MMS19_N.
DR PANTHER; PTHR43655; ATP-DEPENDENT PROTEASE; 1.
DR PANTHER; PTHR43655:SF2; SD01613P; 1.
DR Pfam; PF14500; MMS19_N; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000019103};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 2659..2682
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2722..2741
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 375..450
FT /note="MMS19 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF14500"
FT DOMAIN 557..658
FT /note="MMS19 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF14500"
FT REGION 482..540
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 923..960
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1783..1913
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 840..867
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 489..503
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 504..522
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 929..960
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1783..1797
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1812..1913
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2750 AA; 329919 MW; 3C00B87CBD5D6E0F CRC64;
MASLEELIEE YICPEKVMFT YGKEKKIELI YEKNKDKEEN KIRDNILEKL LFLIENEDYE
DYEENEKGHR EETYKEYEKK SHSTYVNNVR SSNHVLSKDI FDMCPYKIKK WPNNNLIKII
TILKKYYFCS ENMKRGSSIN LVTQLLERID ICDMPLDYFE SIIYFFIKKI EDWHCINGVV
NFFFLMFEKY EHVLKRIYYD NEITELYKNL FIYKNKEKRT KNKNKNENEN ELYIHNDVTI
GDNNNNNNDD GNNNNNNNHY VGDLRTMNCF NDEEENDKID ALMEKDILYE KCGVNVNCCG
SDGNYEDGNY EDGNYEDGNY EDDKCLSSFD EYESDYDNNF YAEPSDYNSS DEEDYIQVRR
INKEQDEGEG LCIVYNILKK LFKHIHAPSY LQGIRLNYYK IILISLEKFR NEIITVPNFI
NKIQVQLENE SDPRNILILF DIIYLLCNAY ISPLETSEDF ISINEYHLYE QRDDEIIKVV
KSNDDDGDVP KSNNNNNNNN NDDNNDDNND DDNNDDDNND DEDVLKSNNN NNNNNDEKRK
KEYINDESLF TYDKETNYLK SLIDISFYYF PIEFINNDGR YDSITEENLE ESFFRCLLSN
KRLGAYVIMN ILDQFYNSEN DEISEKNLKS ILRALELCVP YYGCECASKF ITTVVGLIDL
ECVENNSTDK MVSYFIDILL VFINILNKEP ISTKYNIFNK YLSSMFKKIQ KYVILHKSTY
ENRTYNINEI VEILKGNKEI HKNGDNNKKY IYDDNHKKYI YDDNKKYIYD DNHKKYIYDE
SKMVVDMKED TYRIINSYDY SSHNSSDNED NNNNYFINTN EHNKNNMYGS DESDKNIFTI
IKEKNEIEKI KEKKQKEKKK NRIKLDKFPV LQKILISISK ENNYIFLYIL YTIVKPILKE
CYYLICFLTS QNEVMKKYMK KINDNNKNDN NKNNKNGNNK NNKNGNNKKS NNNNNNLCSN
EDKKFFTRNE KEEEESKYNI RIKKLFNILT SYINFVNNIL ENSVETYKVI KYNIYFLNEI
YIVREIIRIG GDLFVNKYHE CGLELFNILI NLICIHNNDN VLQKELNFDD DNLSIYLINT
IISFFSIVGF NNELIQISEY KKKEVYLYYK CYNKLYNLKI DNNSFNYTDL WREHILQNSF
NFMEDIRKNN EENVLNQNCE FNKNTLLFFL SLINKIIKYK YMHIKNYLNT MLINMSLFIL
KIYVCKEEHM DSYIELLKKL CPMDNITYII FVITNISSFI LHYFYKDVQR ICGDNICGDN
ICGDDKNKSL NNINMIEKDK ETYSDLFQYI YYKQNCNYCL DKNMLKVGYS LKFPNLLFEK
SKNVEDVACR KEEDYEKDIK KPDFEEIKDN NICVSGNVQN VQEEDNNIIK IIVNLDMDND
EIVNYHFNFL LSLTYLHLYY RYVNVTNILF LEDYNKDKTI LSLENIQNEN GCKNKKEMLY
GIFISINIME IMDLCIKYMY EESVLNKFLC LKEMEDEKNK MRKNKRNNVM VEKDYMKIID
DDKENIFYYR NYLNKIKEFI HINHINDLEI TDFDDIGGII SGDKYIPEND GNNDKDKNLN
MINNNLFNYD VLSFKKKKFT NFNLIINTKE LLYMLRIILS INIVYNKIKN ECNITKNNRQ
EKLLFSFCKY IYYKWKGIMN YLFMYFDKIK NRKIFLENLI DHCLNKVDEC IINLDPVKGD
IYCDTFKNMY NLEHNHFHHN LYNSNNIMIH KKYGNHPIYL YKSLNVLLIF FIPTMLGIDN
NISERHIYDL LHLCMYIYML YMYNVTTSFK GIRGPSMLKE QVKEQKEKTG VERSNEGVEE
DDCGDVYVTH GDEDNDGDED EDNDDNDGDE DEDNDGDEDE DNDDNDGDED NGGDEDNDGN
DDDGNDDDGN DDDGNDDDGN DDDDDNDDNN DDNNNDNNDD NNNDNNNDDD FYYSDCDSYD
DYTKRERTFI FKKSFFFKKK RNKINNNIIM NNDVLKSYDS FLNFLNEKNR TMLYCVEKND
IIHKINYDVI RNALQFIDLD LYENIYHCAL QVLSIIIYNK LYKTEELDYV YIHMNIIKYC
TLKLKDSIIF KIVIDHFTNI YQALVNNNLK KNKYEENKNN NNINKINKIN KINIFLPIDS
FLKFISNTFN FTFYEDEKIQ RKIMNRCDYD IMNIHVQALF FLFDNLYCKK EIIHDKTKYD
LYLTHDYYSD KIDYKKNCYT INVHILDNIY TNKIIDEKTE DCNKKINFSW KYLKKININV
YNSVIIKLIN IQSLFQIHKD KSSSSTHEET SDFYFMCHFF ISIFQMFSLF YDLGLYHMHK
QEEKLKKEKK SRHHDMSNDI YDEENIENIY RNMNNKRDKR VLIIFYYTYT SHIYNTLFPN
VYNIDTNTLF CNNNFNSIYF RQHDDFMNTY KNFLVLFLYH MYNYLYFIDI TNKFITITQY
FFLINKFNIS FESSLSYDLI RNKKEVVEFV EKNVDNLCGG YNKKDKDNDA KCGDKYGDKY
GDKYGDKYEL VISSNEHNVD TYKNNKINSI YDLNKIKDNS PIIYNVKYKR KQEKTKINCK
YLTLINLKLI LLSYMSIQEI VDKNYYSILE ICILKGINKV ANFFINKKEY LRNNRKYITQ
VLRYNNDMVK DIFTRDYKKK NRKRKGKKEK TKIERNIKNE LLYEENLENE ENESIIQNII
YDQILPSYSE YKKLIIRKII SMNFILCLRL LYLIINTLNY FLKYENKIYH KEQNEENIKI
LKKNIYFLLS YKSIIMKNVM KMLVSVPLGV TYFYPAANIS WGHQIPYYLK
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