ID W4ME22_9BACT Unreviewed; 924 AA.
AC W4ME22;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Helicase SNF2 {ECO:0000313|EMBL:ETX08181.1};
GN ORFNames=ETSY2_06890 {ECO:0000313|EMBL:ETX08181.1};
OS Candidatus Entotheonella gemina.
OC Bacteria; Nitrospinae/Tectomicrobia group; Candidatus Tectomicrobia;
OC Entotheonella.
OX NCBI_TaxID=1429439 {ECO:0000313|EMBL:ETX08181.1, ECO:0000313|Proteomes:UP000019140};
RN [1] {ECO:0000313|EMBL:ETX08181.1, ECO:0000313|Proteomes:UP000019140}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TSY2 {ECO:0000313|Proteomes:UP000019140};
RX PubMed=24476823; DOI=10.1038/nature12959;
RA Wilson M.C., Mori T., Ruckert C., Uria A.R., Helf M.J., Takada K.,
RA Gernert C., Steffens U.A., Heycke N., Schmitt S., Rinke C., Helfrich E.J.,
RA Brachmann A.O., Gurgui C., Wakimoto T., Kracht M., Crusemann M.,
RA Hentschel U., Abe I., Matsunaga S., Kalinowski J., Takeyama H., Piel J.;
RT "An environmental bacterial taxon with a large and distinct metabolic
RT repertoire.";
RL Nature 506:58-62(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETX08181.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AZHX01000281; ETX08181.1; -; Genomic_DNA.
DR AlphaFoldDB; W4ME22; -.
DR PATRIC; fig|1429439.4.peg.1185; -.
DR HOGENOM; CLU_011520_0_0_7; -.
DR Proteomes; UP000019140; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016817; F:hydrolase activity, acting on acid anhydrides; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd18011; DEXDc_RapA; 1.
DR CDD; cd18793; SF2_C_SNF; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 2.30.30.930; -; 1.
DR Gene3D; 3.30.360.80; -; 1.
DR Gene3D; 6.10.140.1500; -; 1.
DR Gene3D; 6.10.140.2230; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR HAMAP; MF_01821; Helicase_RapA; 1.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR023949; Helicase_RapA.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR022737; RapA_C.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR049730; SNF2/RAD54-like_C.
DR InterPro; IPR000330; SNF2_N.
DR InterPro; IPR040765; Tudor_1_RapA.
DR InterPro; IPR040766; Tudor_2_RapA.
DR PANTHER; PTHR45766; DNA ANNEALING HELICASE AND ENDONUCLEASE ZRANB3 FAMILY MEMBER; 1.
DR PANTHER; PTHR45766:SF3; SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A-LIKE PROTEIN 1; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF12137; RapA_C; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR Pfam; PF18339; Tudor_1_RapA; 1.
DR Pfam; PF18337; Tudor_RapA; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:ETX08181.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000019140};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 163..335
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 450..601
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 924 AA; 104026 MW; BF9431F1F09BC948 CRC64;
MTDYVVGQRW ISDTEPDLGL GHIQHVEPRR VTISFEASGQ TRLYATSSAP LTRVRFNVGD
RIQSQHGWHM TVDRVEDGEG LLTYFGERDD GSAVALPEAE LAHHIHFNQP KERLFAGQID
SDSWFRLRLE ALRHQQELAR LPVRGLIGGR VDLIPHQLYI ADEVSQRRAP RVLLADEVGL
GKTIEAGLIL HRLLLGERIG RVLVIVPDAL LYQWLVEMLR RFNVRFSILD EDRFEAWKEA
DPEVNPFLEE PHILCGLDFL TQHRGAAAKA LAGEWDMLIV DEAHHLQWSP EAASPAYRLV
EALAMMTPSL LLLTATPEQL GRAGHFARLR LLDAQRFHDF DAFLEEESGY PETAAVATVL
GGNDERLSAQ DVALLSARLT DDDIQPLLQR LETGTAEPED RERLLDLLID RHGTGRVLFR
NTRAAVQGFP ARRLMAHALT EDGADTRLAW LVQQLKTLVP ERALLICQQA QTAIGLAAAL
RETVGLHAAL FHERMSIVER DRAAAYFADE ESGTPLLICS EIGSEGRNFQ FAHRLILFDL
PENPDLLEQR IGRLDRIGQQ HTVHIHVPYL ENSREAFWLR WYHEGLDAFE HTCPVGTAVL
NTLEEEFGQS LSALAADPDR IDAIIDRTRE LRTAQLVLLE QGRDRLLELN SCRPQRARVL
CESVAAADDD PGVRHFMERT FDCYGVHFED HSPGCWIAQP SDHMYITQFP GLPEEGCTLT
TSREMALRRE DIQFLSWDHP LARGALDLIL HSREGNVTVA AIQLASVPAG QVLVESFFRL
DCPADLRLNA QRYLPPDLLR VLVDPEGCDC AVDIDADTVS KSAVSVPLHL VRDLIESQYE
TVRRQVMAAE VLAEEQAPRL REQSVAHMQA ELGAEFNRLV ALAKVNPSIR SDELQALQDD
MADLREALSQ SRMQMEAVRV LFTH
//
