ID   W4ME42_9BACT            Unreviewed;       355 AA.
AC   W4ME42;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   RecName: Full=AMP-dependent synthetase/ligase domain-containing protein {ECO:0008006|Google:ProtNLM};
DE   Flags: Fragment;
GN   ORFNames=ETSY2_05360 {ECO:0000313|EMBL:ETX08450.1};
OS   Candidatus Entotheonella gemina.
OC   Bacteria; Nitrospinae/Tectomicrobia group; Candidatus Tectomicrobia;
OC   Entotheonella.
OX   NCBI_TaxID=1429439 {ECO:0000313|EMBL:ETX08450.1, ECO:0000313|Proteomes:UP000019140};
RN   [1] {ECO:0000313|EMBL:ETX08450.1, ECO:0000313|Proteomes:UP000019140}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TSY2 {ECO:0000313|Proteomes:UP000019140};
RX   PubMed=24476823; DOI=10.1038/nature12959;
RA   Wilson M.C., Mori T., Ruckert C., Uria A.R., Helf M.J., Takada K.,
RA   Gernert C., Steffens U.A., Heycke N., Schmitt S., Rinke C., Helfrich E.J.,
RA   Brachmann A.O., Gurgui C., Wakimoto T., Kracht M., Crusemann M.,
RA   Hentschel U., Abe I., Matsunaga S., Kalinowski J., Takeyama H., Piel J.;
RT   "An environmental bacterial taxon with a large and distinct metabolic
RT   repertoire.";
RL   Nature 506:58-62(2014).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ETX08450.1}.
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DR   EMBL; AZHX01000221; ETX08450.1; -; Genomic_DNA.
DR   AlphaFoldDB; W4ME42; -.
DR   HOGENOM; CLU_000022_2_12_7; -.
DR   Proteomes; UP000019140; Unassembled WGS sequence.
DR   Gene3D; 3.30.300.30; -; 1.
DR   Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR   InterPro; IPR010071; AA_adenyl_domain.
DR   InterPro; IPR025110; AMP-bd_C.
DR   InterPro; IPR045851; AMP-bd_C_sf.
DR   InterPro; IPR020459; AMP-binding.
DR   InterPro; IPR020845; AMP-binding_CS.
DR   InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR   InterPro; IPR042099; ANL_N_sf.
DR   NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR   PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR   PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR   Pfam; PF00501; AMP-binding; 1.
DR   Pfam; PF13193; AMP-binding_C; 1.
DR   PRINTS; PR00154; AMPBINDING.
DR   SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR   PROSITE; PS00455; AMP_BINDING; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000019140}.
FT   DOMAIN          3..227
FT                   /note="AMP-dependent synthetase/ligase"
FT                   /evidence="ECO:0000259|Pfam:PF00501"
FT   DOMAIN          286..355
FT                   /note="AMP-binding enzyme C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13193"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:ETX08450.1"
FT   NON_TER         355
FT                   /evidence="ECO:0000313|EMBL:ETX08450.1"
SQ   SEQUENCE   355 AA;  38905 MW;  1E17BEA9935CB131 CRC64;
     PHPLLPSHPA YVIYTSGSTG QPKGVVVPHR QVARLFGVTH AWFDFGPDDV WPLLHSYAFD
     FSVWELWGAL LYGGQLVLVS KRVTQSPAEL LELLVKHRVT ILNQTPSAFY ELMQAEGEHS
     ELGRNLRLRR IIFGGEALEL GRLAPWYERH GDTAPVLVNM YGITETTVHV SYLPLVREWA
     RVGEGSLVGG NIPDLRLYVL DAGLGLMPVG VAGELYVAGA GLARGYLNRA GLTAERFVAD
     PYGIEPGSRM YRTGDLARWR PDGTLEFLGR ADDQVKIRGF RIELGEIASV LAAQASVAQA
     AVVVREESPG DPQLVAYVVA SSGARPEGGN LRHVLSERLP DYMVPRAIVE LETLP
//