ID   W4PE35_9BACE            Unreviewed;       787 AA.
AC   W4PE35;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   24-JAN-2024, entry version 26.
DE   RecName: Full=beta-N-acetylhexosaminidase {ECO:0000256|ARBA:ARBA00012663};
DE            EC=3.2.1.52 {ECO:0000256|ARBA:ARBA00012663};
GN   ORFNames=JCM6294_920 {ECO:0000313|EMBL:GAE18071.1};
OS   Bacteroides pyogenes DSM 20611 = JCM 6294.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae;
OC   Bacteroides.
OX   NCBI_TaxID=1121100 {ECO:0000313|EMBL:GAE18071.1, ECO:0000313|Proteomes:UP000018842};
RN   [1] {ECO:0000313|Proteomes:UP000018842}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 6294 {ECO:0000313|Proteomes:UP000018842};
RA   Sakamoto M., Oshima K., Suda W., Kitamura K., Iida T., Hattori M.,
RA   Ohkuma M.;
RT   "Draft Genome Sequences of Three Strains of Bacteroides pyogenes Isolated
RT   from a Cat and Swine.";
RL   Genome Announc.2:e01242-13(2014).
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC       {ECO:0000256|ARBA:ARBA00006285}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAE18071.1}.
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DR   EMBL; BAIR01000005; GAE18071.1; -; Genomic_DNA.
DR   AlphaFoldDB; W4PE35; -.
DR   STRING; 1121100.GCA_000428105_00526; -.
DR   eggNOG; COG3525; Bacteria.
DR   Proteomes; UP000018842; Unassembled WGS sequence.
DR   GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   CDD; cd06563; GH20_chitobiase-like; 1.
DR   Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR   InterPro; IPR000421; FA58C.
DR   InterPro; IPR026876; Fn3_assoc_repeat.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR015883; Glyco_hydro_20_cat.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR029018; Hex-like_dom2.
DR   InterPro; IPR015882; HEX_bac_N.
DR   PANTHER; PTHR22600; BETA-HEXOSAMINIDASE; 1.
DR   PANTHER; PTHR22600:SF21; BETA-HEXOSAMINIDASE A; 1.
DR   Pfam; PF00754; F5_F8_type_C; 1.
DR   Pfam; PF13287; Fn3_assoc; 1.
DR   Pfam; PF00728; Glyco_hydro_20; 1.
DR   Pfam; PF02838; Glyco_hydro_20b; 1.
DR   PRINTS; PR00738; GLHYDRLASE20.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
DR   SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR   PROSITE; PS50022; FA58C_3; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT   DOMAIN          622..762
FT                   /note="F5/8 type C"
FT                   /evidence="ECO:0000259|PROSITE:PS50022"
FT   ACT_SITE        346
FT                   /note="Proton donor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR625705-1"
SQ   SEQUENCE   787 AA;  88603 MW;  8DDFFF2C3010A733 CRC64;
     MKYLYLLTTN FYFMKQLLRL TGCLAIAGLA VSCQSVQKEA DYRIIPLPQE IATAQGNPFV
     LKSGVKILYP EGNEKMQRNA EFLAGYLKEA TGKSFSMEAG TEGKHAIVLT LGLDAENPEA
     YRLSVAESGI TVAAPTEAGV FYGIQSLRKS LPVAMNAEIS LPAAEINDYP RFSYRGAHFD
     VARHFFTLDE VKTYIDMMVL HNMNRLHWHL TEDQGWRLEI KKYPKLTEIG SVRKETMVGK
     NFDKFDGKPH GGFYTQEEAK EIVKYAAERY ITVIPEIDLP GHMQAALAAY PELGCTGGPY
     EVWTKWGVSD NVLCAGNDRT LEFIDDVLTE VMEIFPSEYI HVGGDECPKT QWEKCPKCQA
     RIKALGLKSD KEHTKEERLQ SFVINHAEKF LNEHGRQIIG WDEILEGGLA PNATVMSWRG
     EAGGIEAAKQ NHDVIMTPNT YLYFDYYQSK DTKNEPLAIG GYLPVERVYG YEPMPSSLTP
     EQQKYIKGVQ ANLWTEYIPT FEQAQYMVLP RWAALAEVQW TMPDKKNYED FLSRLPRLIE
     WYDAEEYNYA KHVFDVKAEF TPNTEDGTLD VTLVTVDNAP IHYTLDGSEP TASSPKYEGV
     LKLKEDTRLM AVAIRPTGNS RVVSEEFHFN KASMKPIVAN QPVNRQYMFK GAPSLVDGLR
     GGDNYNTGRW IAFRNNDMDM TIDLRQPTEI SSVSIAAFAA KGDWVFDARG LAVEVSDDGK
     SFTKVASEEY PAMKQSDNDG ICEHKLAFTP VKTRFVRVVA LSEKAIPSWH GGKGKPGFLF
     VDEIVID
//