ID W4RRU7_9BACI Unreviewed; 479 AA.
AC W4RRU7;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Membrane protein {ECO:0000313|EMBL:GAE46837.1};
GN ORFNames=JCM21738_3764 {ECO:0000313|EMBL:GAE46837.1};
OS Mesobacillus boroniphilus JCM 21738.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Mesobacillus.
OX NCBI_TaxID=1294265 {ECO:0000313|EMBL:GAE46837.1, ECO:0000313|Proteomes:UP000018949};
RN [1] {ECO:0000313|EMBL:GAE46837.1, ECO:0000313|Proteomes:UP000018949}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 21738 {ECO:0000313|EMBL:GAE46837.1,
RC ECO:0000313|Proteomes:UP000018949};
RA Hattori M., Oshima K., Inaba H., Suda W., Sakamoto M., Iino T.,
RA Kitahara M., Oshida Y., Iida T., Kudo T., Itoh T., Ahmed I., Ohkuma M.;
RT "NBRP : Genome information of microbial organism related human and
RT environment.";
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the resistance-nodulation-cell division (RND)
CC (TC 2.A.6) family. MmpL subfamily. {ECO:0000256|ARBA:ARBA00010157}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAE46837.1}.
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DR EMBL; BAUW01000055; GAE46837.1; -; Genomic_DNA.
DR AlphaFoldDB; W4RRU7; -.
DR eggNOG; COG1511; Bacteria.
DR eggNOG; COG2409; Bacteria.
DR Proteomes; UP000018949; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 1.
DR InterPro; IPR004869; MMPL_dom.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF6; MEMBRANE PROTEIN SCO0839-RELATED; 1.
DR Pfam; PF03176; MMPL; 1.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000018949};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 146..175
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 195..216
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 244..265
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 271..294
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 322..343
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 7..326
FT /note="Membrane transport protein MMPL"
FT /evidence="ECO:0000259|Pfam:PF03176"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 37..64
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 479 AA; 52999 MW; DC1EF55F335E94A8 CRC64;
MPDEYSSTLA GKIMDDVRKQ EGGGDDTQVA LVFHSEKKLT QEEIKEAERA ISELEKNSEE
IGITDILTHF NEESLKDQLV SDDGKSILTS VTVNWNDREP SEVSKLLYET IENVKVDHYY
TSQWLINEDL MSSSEEGLKK TEGITVVFIL VVLLLVFRSV VAPVIPLLTV GMSYLVSQSI
VAMLVDQFDF PLSNYTQIFL VAVLFGIGTD YCILLLSRFK EEMTHHESVP SAIVATYKNA
GRTVFFSGVA VMIGFAAIGF SQFILYQSAA AVAIGVAMLL LGLFTIVPFF MAVLGQKIFW
PSKQSAEHGE SKLWGTVGSF SLARPFLSLL IVAAVCVPFL FAYDGELSYN SLDEISGDVN
SINAFNAIAD SFGPGESMPT QVILKNDERM DSAEYIELAE NISSELEKVD LVDTVRSVTR
PTGEPIEDFF VSKQAETLVP ALGKEKKVWI KSVKAFRELN LSCQNQLQNW KAQQMASTS
//
