ID W4VHT1_9BACI Unreviewed; 458 AA.
AC W4VHT1;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=O-acetylhomoserine sulfhydrylase {ECO:0000313|EMBL:GAE92772.1};
GN ORFNames=JCM21714_1790 {ECO:0000313|EMBL:GAE92772.1};
OS Gracilibacillus boraciitolerans JCM 21714.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Gracilibacillus.
OX NCBI_TaxID=1298598 {ECO:0000313|EMBL:GAE92772.1, ECO:0000313|Proteomes:UP000019102};
RN [1] {ECO:0000313|EMBL:GAE92772.1, ECO:0000313|Proteomes:UP000019102}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 21714 {ECO:0000313|EMBL:GAE92772.1,
RC ECO:0000313|Proteomes:UP000019102};
RA Ahmed I., Oshima K., Suda W., Kitamura K., Iida T., Ohmori Y., Fujiwara T.,
RA Hattori M., Ohkuma M.;
RT "Draft Genome Sequence of the Boron-Tolerant and Moderately Halotolerant
RT Bacterium Gracilibacillus boraciitolerans JCM 21714T.";
RL Genome Announc. 2:e00097-14(2014).
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|RuleBase:RU362118};
CC -!- SIMILARITY: Belongs to the trans-sulfuration enzymes family.
CC {ECO:0000256|ARBA:ARBA00009077, ECO:0000256|RuleBase:RU362118}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAE92772.1}.
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DR EMBL; BAVS01000007; GAE92772.1; -; Genomic_DNA.
DR AlphaFoldDB; W4VHT1; -.
DR STRING; 1298598.JCM21714_1790; -.
DR eggNOG; COG2873; Bacteria.
DR Proteomes; UP000019102; Unassembled WGS sequence.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0016765; F:transferase activity, transferring alkyl or aryl (other than methyl) groups; IEA:InterPro.
DR GO; GO:0019346; P:transsulfuration; IEA:InterPro.
DR CDD; cd00614; CGS_like; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR000277; Cys/Met-Metab_PyrdxlP-dep_enz.
DR InterPro; IPR006235; OAc-hSer/O-AcSer_sulfhydrylase.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR NCBIfam; TIGR01326; OAH_OAS_sulfhy; 1.
DR PANTHER; PTHR43797; HOMOCYSTEINE/CYSTEINE SYNTHASE; 1.
DR PANTHER; PTHR43797:SF2; HOMOCYSTEINE_CYSTEINE SYNTHASE; 1.
DR Pfam; PF01053; Cys_Met_Meta_PP; 1.
DR PIRSF; PIRSF001434; CGS; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR PROSITE; PS00868; CYS_MET_METAB_PP; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|PIRSR:PIRSR001434-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000019102}.
FT COILED 276..303
FT /evidence="ECO:0000256|SAM:Coils"
FT MOD_RES 198
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR001434-2"
SQ SEQUENCE 458 AA; 49809 MW; 27DD92398BABCFAE CRC64;
MGGQAPDPTT GSRAVPIYQT TSYVFHDTEH AERLFALDEP GNIYSRIGNP TVDVFEKRLA
LLEDGGVAAV ATASGMSAIT LSILNLASAG DEIVAGGVNL YGGTYNLFNV TLPRYGIKVK
FVDPTDPENF KAAITDQTKA VYGEIIGNPG LQVLDVEKVS EIAHDAGIPL IVDNTFATPF
GCKPIILGAD IVVHSATKWI GGHGTSIGGI IIDGGRFNWN SEKYPAFTEP DPSYNGIRYA
VDFGTLAFIT KVRVQLLRDF GAALSPFNAF QLIQGLETLH LRIERHNQNA QELAEYLEDH
EAVDWVRYPG LESHPSHDLA KRILNNGFGS IIVFGIKGGK DAGRKLINNV ALWSHVANVG
DAKSLIIHPA STTHQQLTKE ELKTTGVTEE LVRLSVGIES IRDIKNDLEQ AIVKATGIGE
DKQQQIIVND EGIIKWALNS PHMNAIQKMA KKKQDKKR
//
