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Database: UniProt
Entry: W4YHF0_STRPU
LinkDB: W4YHF0_STRPU
Original site: W4YHF0_STRPU 
ID   W4YHF0_STRPU            Unreviewed;       856 AA.
AC   W4YHF0;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   30-AUG-2017, entry version 19.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:SPU_015194-tr};
OS   Strongylocentrotus purpuratus (Purple sea urchin).
OC   Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa;
OC   Echinoidea; Euechinoidea; Echinacea; Echinoida; Strongylocentrotidae;
OC   Strongylocentrotus.
OX   NCBI_TaxID=7668 {ECO:0000313|EnsemblMetazoa:SPU_015194-tr, ECO:0000313|Proteomes:UP000007110};
RN   [1] {ECO:0000313|EnsemblMetazoa:SPU_015194-tr}
RP   NUCLEOTIDE SEQUENCE.
RA   Murali S., Liu Y., Vee V., English A., Wang M., Skinner E., Han Y.,
RA   Muzny D.M., Worley K.C., Gibbs R.A.;
RT   "Genome sequencing for Strongylocentrotus purpuratus.";
RL   Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:SPU_015194-tr}
RP   IDENTIFICATION.
RG   EnsemblMetazoa;
RL   Submitted (JUN-2015) to UniProtKB.
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DR   EMBL; AAGJ04130071; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAGJ04130072; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 7668.SPU_015194tr; -.
DR   EnsemblMetazoa; SPU_015194-tr; SPU_015194-tr; SPU_015194.
DR   eggNOG; KOG3609; Eukaryota.
DR   eggNOG; ENOG410XQ0Y; LUCA.
DR   OrthoDB; EOG09371R9T; -.
DR   Proteomes; UP000007110; Unassembled WGS sequence.
DR   GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR   GO; GO:0015279; F:store-operated calcium channel activity; IBA:GO_Central.
DR   GO; GO:0006828; P:manganese ion transport; IBA:GO_Central.
DR   GO; GO:0051480; P:regulation of cytosolic calcium ion concentration; IBA:GO_Central.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR013555; TRP_dom.
DR   InterPro; IPR002153; TRPC_channel.
DR   PANTHER; PTHR10117; PTHR10117; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF08344; TRP_2; 1.
DR   PRINTS; PR01097; TRNSRECEPTRP.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000007110};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007110};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    164    186       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    198    219       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    225    244       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    265    287       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    338    360       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    381    403       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    450    475       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       33     76       TRP_2. {ECO:0000259|Pfam:PF08344}.
FT   DOMAIN      202    485       Ion_trans. {ECO:0000259|Pfam:PF00520}.
SQ   SEQUENCE   856 AA;  96676 MW;  F67243CD6D7E3FCA CRC64;
     MAAIRNNFII VQYLLKAGAE RIREPKLEGL SEASLSEVVE YLDIYRALSS PAYLGLAHPN
     ALSNAFKLTG RLRKIAGLWE AVNKEFYDLA DQVEQFCASL LDYVANSVEL GTLFRQSDDP
     EVVHVVAQVK NAVDFEQKAF VAHAYTQKIM SINFYRNIDT HTPWFGFLSL LTMFGYPFIC
     LAYILVQHPR LKRWLSIPYI KLCIFFGSDL AIFVCYAALC VVNDPRITDI ILVFILIFCV
     ALSWKHICDI MEYGIGDFLG YGANILESIT LIISFVLLMC KSITLLLDVY ETRAMKRHDK
     RVAMVNNVTV TSDLKLSNVT VTDRLEQFVS LDWNDPQIVL YVLLGVVVLP NAIRAFTTAL
     NSYQDLYSIW ESTVGALSDM FKFVTVFAIF HFAFAVGLFG IYVTQKEIYA EDLADEGYHS
     IPNALLTLWW VFNSMGDKAE LNGQVTFVNV VHIVIVGIYY TVALVLINTL IAILASKFES
     IAENSDTEWK FGRTKMWLRF IRTDIALPPP FNIVPTTGFI IRLLKNCFSL CTAGCTQTSQ
     KQPEKSEEKT NHDGNARKVM KEILKRYNTT QIEKPDDEES FGIDDIRQIN QDFVTVKFNV
     QTKLQVIKNM IDAIWLTIGN IECNFPIMDD IKDKIPVTRT EVIDMFQTNY PVLDDDIGNL
     QVVIEDVMEE LGYRPEVAPK PRRKEIVQDV IDGPPIVLPD PTPAPTPEPT PEPTPEPTPE
     PTPEPTPEPT PEPTPEPTRE PTPEPTPEPT PEPEKTLIER VIDFFTELSD NNEIGQDVID
     GPPIVLPDPT PEPTTEPTTE PTPKPKMTLT QKMANMFAEG RTVETDDEVT EEVQKFRLGF
     IDRVIGFVKG SSDDND
//
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