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Database: UniProt
Entry: W4ZHT6_STRPU
LinkDB: W4ZHT6_STRPU
Original site: W4ZHT6_STRPU 
ID   W4ZHT6_STRPU            Unreviewed;      1795 AA.
AC   W4ZHT6;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   07-JUN-2017, entry version 31.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EnsemblMetazoa:SPU_027748-tr};
OS   Strongylocentrotus purpuratus (Purple sea urchin).
OC   Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa;
OC   Echinoidea; Euechinoidea; Echinacea; Echinoida; Strongylocentrotidae;
OC   Strongylocentrotus.
OX   NCBI_TaxID=7668 {ECO:0000313|EnsemblMetazoa:SPU_027748-tr, ECO:0000313|Proteomes:UP000007110};
RN   [1] {ECO:0000313|EnsemblMetazoa:SPU_027748-tr}
RP   NUCLEOTIDE SEQUENCE.
RA   Murali S., Liu Y., Vee V., English A., Wang M., Skinner E., Han Y.,
RA   Muzny D.M., Worley K.C., Gibbs R.A.;
RT   "Genome sequencing for Strongylocentrotus purpuratus.";
RL   Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EnsemblMetazoa:SPU_027748-tr}
RP   IDENTIFICATION.
RG   EnsemblMetazoa;
RL   Submitted (JUN-2015) to UniProtKB.
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DR   EMBL; AAGJ04096900; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAGJ04096901; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAGJ04096902; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAGJ04096903; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAGJ04096904; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAGJ04096905; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAGJ04096906; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AAGJ04096907; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   STRING; 7668.SPU_027748tr; -.
DR   EnsemblMetazoa; SPU_027748-tr; SPU_027748-tr; SPU_027748.
DR   eggNOG; KOG2301; Eukaryota.
DR   eggNOG; ENOG410XNP6; LUCA.
DR   OMA; MLGDSAM; -.
DR   OrthoDB; EOG091G00F9; -.
DR   Proteomes; UP000007110; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0005261; F:cation channel activity; IBA:GO_Central.
DR   GO; GO:0006816; P:calcium ion transport; IBA:GO_Central.
DR   GO; GO:0034220; P:ion transmembrane transport; IBA:GO_Central.
DR   GO; GO:0086010; P:membrane depolarization during action potential; IBA:GO_Central.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR028823; NALCN.
DR   PANTHER; PTHR10037:SF252; PTHR10037:SF252; 1.
DR   Pfam; PF00520; Ion_trans; 5.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000007110};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000007110};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    182    199       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    267    294       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    358    377       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    397    416       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    482    504       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    547    573       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    593    622       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    928    952       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    964    982       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1002   1020       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1064   1087       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1180   1206       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1257   1274       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1280   1303       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1315   1332       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1375   1397       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   1463   1485       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       50    298       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      356    563       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      564    626       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      934   1207       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN     1255   1496       Ion_trans. {ECO:0000259|Pfam:PF00520}.
SQ   SEQUENCE   1795 AA;  206257 MW;  4243FF6C13490914 CRC64;
     MVLKKRKQST TRLGDDIAIA DYGADENITD NAKIQWVNQP WVRKLLRGAA MVSFISLCFN
     TPKTFEKIPS MEYMTLVVDS VVTLLFFSET IFKMTTRGII FGEYAYLRDN WGRFDTSMVL
     SLWVSILLQI CQIANVVPKY TPYTILRAPR PFIMIRSFRV YLKFKLPKAR VKSIFKRSGQ
     QVWSVTIFLV FFLVLYGMLG VQMFGDLSTH CVKKEIDNQT FSALQKGHSI FNKICVSIFT
     VYESASLEGW VFIMYKVTDS FPSWRGYFFF ITMIFFLAWL VKNVFIAVII ETFAEIRVQF
     RQMWTRGGAA QSFDSKVEVL QDDGTYTPWK LTIVDENNSR GPAPMCCQRV LESRSCHFFI
     LGMVAIDAVL ASTYNMFYPD NEDLKNRYHK GLYIAQVGFT LLFDVEVLFK VWCLGFRGYF
     KRSLHKFELC LAIGNSIRIM DPERLYSSQL AYFQVMRCFR LIKLSPTLED FSRKIFGPFI
     KLGTLILFTM SSLILVSVIS LQLFCYVEDL KQFDTFPTAV MSVFQILTQE GWIEVVDECF
     LACKEELSSL VALYFVTIHV FSSSAFMSMF QILTQKGWAI VMYECMLAAD NNALAPVIAI
     YFIAYHLFAT VIVLSLFVAV ILDNLELGED FKGMKQMKAS EKNTAAKVLP RRLRVFQKFP
     DKPQMVMLSK IPSEFTLPKI RDSFIRQFVE TGTDMERLLK RSANRESSGT LLALALPPAT
     YACPTSPLYL MSRRLPAFTT QIQGKLQKKT GVNCIVRDSA HQRVVSLGFS AVGVRGRMLS
     EYGSRDRRLR ALRGSIRGHK PMESIKDNSD IANRNVSFNI KVIQERKQQA VQKRQTNQKV
     IEFCQHLPLV FDSGPQVKQH SNIHYHRNAT EEDLRENPPY HDMPLFAVGR ESNLRKFCTG
     IVYARYNATH TDESGMVIKR RYQEIHDFVA MVTYMTWCSI VVTTATCISM MYESPVNRVM
     DNKVLVIAEY IFVIFMGSEM ILKILADGLF FTPKALIRDV GGFLDVFIYL ISVIFLFWMP
     KNVQPASLAH VFLVLRCCRP LRIFALVPHL RKLFYELLRS FKEIFLVSVL LLALIFVFAS
     YGVQIFATRL AKCNDPNITE ERDCVGEFRI MVSVVKTHKP RSPEDELPTF LVPRVWANPR
     NFNFDNLGNA LLALFEVLSL EGWLEVRDII INQTNMWHTL YIHIFVFIGC MIGLTLFVGV
     VISNYFENKG TTLLTIDQRR WQDLKGRLQL AQPLHLPPRP DRSRFRAKLY DLSQHKYFKR
     FIAFLVLVNF FLLSSKPRSL AYISVVLTLM FVLEVILKCI SLSPIGYWHS RRNRYDLLVT
     LMGVAWLILH FTNMNNTSFA FGAATVLFRF FTITGKHPTL KMLMMTIVVS CGKSFFIIVG
     LFLLITFYAF LGVVLFGKVK YGEHLGRHAN FENAPNAMAT LFRIVTGEDW NKIMHDCMIS
     EPHCSKRGEN YWETDCGNSI ASMVYFCSFY VLIAYIVINL LVGIIMENFS LFYSNEEDAL
     LSYADIKNFQ ITWNMVDIHR KGVIPVSRVK FVLRLLRGRL EVDMEKDHLL YKHMCCEIEK
     MRNGQDVTFH DVLSMLSYRS VDIRKSLQLD ELLAREELEY NIEEEVAKET IRNWLDKCLI
     RMRAKEKSHH PSYSNPFYGG EKPERLVVPP AFITTPSPPK EDTNKSKEET PVLDNIAPNP
     ETNKDSTKKK LAFSPNAQTK SEHGAPSSPG HKLLVPTLSE GNVKPDGEDS ASLRPRRSNR
     RYQTGSTSSS TSVTPVSSTC SAPVYPRSTS APTATKEVQD WWKEQLHYDS GSEED
//
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