ID W5JU08_ANODA Unreviewed; 219 AA.
AC W5JU08;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=SREBP regulating gene protein {ECO:0000256|ARBA:ARBA00023485};
GN ORFNames=AND_001810 {ECO:0000313|EMBL:ETN66415.1};
OS Anopheles darlingi (Mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=43151 {ECO:0000313|EMBL:ETN66415.1};
RN [1] {ECO:0000313|EMBL:ETN66415.1, ECO:0000313|Proteomes:UP000000673}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=20920257; DOI=10.1186/1471-2164-11-529;
RA Mendes N.D., Freitas A.T., Vasconcelos A.T., Sagot M.F.;
RT "Combination of measures distinguishes pre-miRNAs from other stem-loops in
RT the genome of the newly sequenced Anopheles darlingi.";
RL BMC Genomics 11:529-529(2010).
RN [2] {ECO:0000313|EMBL:ETN66415.1}
RP NUCLEOTIDE SEQUENCE.
RA Almeida L.G., Nicolas M.F., Souza R.C., Vasconcelos A.T.R.;
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:ETN66415.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23761445;
RA Marinotti O., Cerqueira G.C., de Almeida L.G., Ferro M.I., Loreto E.L.,
RA Zaha A., Teixeira S.M., Wespiser A.R., Almeida E Silva A.,
RA Schlindwein A.D., Pacheco A.C., Silva A.L., Graveley B.R., Walenz B.P.,
RA Lima Bde A., Ribeiro C.A., Nunes-Silva C.G., de Carvalho C.R., Soares C.M.,
RA de Menezes C.B., Matiolli C., Caffrey D., Araujo D.A., de Oliveira D.M.,
RA Golenbock D., Grisard E.C., Fantinatti-Garboggini F., de Carvalho F.M.,
RA Barcellos F.G., Prosdocimi F., May G., Azevedo Junior G.M., Guimaraes G.M.,
RA Goldman G.H., Padilha I.Q., Batista Jda S., Ferro J.A., Ribeiro J.M.,
RA Fietto J.L., Dabbas K.M., Cerdeira L., Agnez-Lima L.F., Brocchi M.,
RA de Carvalho M.O., Teixeira Mde M., Diniz Maia Mde M., Goldman M.H.,
RA Cruz Schneider M.P., Felipe M.S., Hungria M., Nicolas M.F., Pereira M.,
RA Montes M.A., Cantao M.E., Vincentz M., Rafael M.S., Silverman N.,
RA Stoco P.H., Souza R.C., Vicentini R., Gazzinelli R.T., Neves Rde O.,
RA Silva R., Astolfi-Filho S., Maciel T.E., Urmenyi T.P., Tadei W.P.,
RA Camargo E.P., de Vasconcelos A.T.;
RT "The genome of Anopheles darlingi, the main neotropical malaria vector.";
RL Nucleic Acids Res. 41:7387-7400(2013).
RN [4] {ECO:0000313|EnsemblMetazoa:ADAC001810-PA}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC {ECO:0000256|ARBA:ARBA00004194}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004194}. Membrane
CC {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004167}.
CC -!- SIMILARITY: Belongs to the SPRING family.
CC {ECO:0000256|ARBA:ARBA00023461}.
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DR EMBL; ADMH02000457; ETN66415.1; -; Genomic_DNA.
DR AlphaFoldDB; W5JU08; -.
DR EnsemblMetazoa; ADAC001810-RA; ADAC001810-PA; ADAC001810.
DR VEuPathDB; VectorBase:ADAC001810; -.
DR VEuPathDB; VectorBase:ADAR2_007636; -.
DR eggNOG; KOG3136; Eukaryota.
DR HOGENOM; CLU_079455_0_0_1; -.
DR OMA; QHICKSC; -.
DR OrthoDB; 63629at2759; -.
DR Proteomes; UP000000673; Unassembled WGS sequence.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:2000640; P:positive regulation of SREBP signaling pathway; IEA:InterPro.
DR InterPro; IPR019352; SPRING1.
DR PANTHER; PTHR13481:SF0; SREBP REGULATING GENE PROTEIN; 1.
DR PANTHER; PTHR13481; UNCHARACTERIZED; 1.
DR Pfam; PF10218; SPRING1; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000673};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 14..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 219 AA; 24949 MW; F83FFD2F191EEFAA CRC64;
MCYAILAKFV RRRWVLAIIF ILSLSYCMIH LIRKNNNLNL HGDFLQSQLL RHKEIVWTKP
ASLPSANETE EKLPSSCRNS VQGKTLIVDD RGYVCPRAAL LQNGCCNDIS KRKLYPCSSC
LPNRCCAVYE YCVACCLHPD MRPILEEVLA KANGRQVALY ATVVDQFELC LTKCRTNSKS
VQNENKYRNP EQKYCYGENN EAWLSSSEND GNKVIPDDA
//
