ID W5JW66_ANODA Unreviewed; 525 AA.
AC W5JW66;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 24-JAN-2024, entry version 40.
DE SubName: Full=Selenocysteine-specific elongation factor {ECO:0000313|EMBL:ETN67204.1};
GN ORFNames=AND_000992 {ECO:0000313|EMBL:ETN67204.1};
OS Anopheles darlingi (Mosquito).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; Culicidae;
OC Anophelinae; Anopheles.
OX NCBI_TaxID=43151 {ECO:0000313|EMBL:ETN67204.1};
RN [1] {ECO:0000313|EMBL:ETN67204.1, ECO:0000313|Proteomes:UP000000673}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=20920257; DOI=10.1186/1471-2164-11-529;
RA Mendes N.D., Freitas A.T., Vasconcelos A.T., Sagot M.F.;
RT "Combination of measures distinguishes pre-miRNAs from other stem-loops in
RT the genome of the newly sequenced Anopheles darlingi.";
RL BMC Genomics 11:529-529(2010).
RN [2] {ECO:0000313|EMBL:ETN67204.1}
RP NUCLEOTIDE SEQUENCE.
RA Almeida L.G., Nicolas M.F., Souza R.C., Vasconcelos A.T.R.;
RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:ETN67204.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=23761445;
RA Marinotti O., Cerqueira G.C., de Almeida L.G., Ferro M.I., Loreto E.L.,
RA Zaha A., Teixeira S.M., Wespiser A.R., Almeida E Silva A.,
RA Schlindwein A.D., Pacheco A.C., Silva A.L., Graveley B.R., Walenz B.P.,
RA Lima Bde A., Ribeiro C.A., Nunes-Silva C.G., de Carvalho C.R., Soares C.M.,
RA de Menezes C.B., Matiolli C., Caffrey D., Araujo D.A., de Oliveira D.M.,
RA Golenbock D., Grisard E.C., Fantinatti-Garboggini F., de Carvalho F.M.,
RA Barcellos F.G., Prosdocimi F., May G., Azevedo Junior G.M., Guimaraes G.M.,
RA Goldman G.H., Padilha I.Q., Batista Jda S., Ferro J.A., Ribeiro J.M.,
RA Fietto J.L., Dabbas K.M., Cerdeira L., Agnez-Lima L.F., Brocchi M.,
RA de Carvalho M.O., Teixeira Mde M., Diniz Maia Mde M., Goldman M.H.,
RA Cruz Schneider M.P., Felipe M.S., Hungria M., Nicolas M.F., Pereira M.,
RA Montes M.A., Cantao M.E., Vincentz M., Rafael M.S., Silverman N.,
RA Stoco P.H., Souza R.C., Vicentini R., Gazzinelli R.T., Neves Rde O.,
RA Silva R., Astolfi-Filho S., Maciel T.E., Urmenyi T.P., Tadei W.P.,
RA Camargo E.P., de Vasconcelos A.T.;
RT "The genome of Anopheles darlingi, the main neotropical malaria vector.";
RL Nucleic Acids Res. 41:7387-7400(2013).
RN [4] {ECO:0000313|EnsemblMetazoa:ADAC000992-PA}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (JUN-2015) to UniProtKB.
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DR EMBL; ADMH02000262; ETN67204.1; -; Genomic_DNA.
DR AlphaFoldDB; W5JW66; -.
DR STRING; 43151.W5JW66; -.
DR EnsemblMetazoa; ADAC000992-RA; ADAC000992-PA; ADAC000992.
DR VEuPathDB; VectorBase:ADAC000992; -.
DR VEuPathDB; VectorBase:ADAR2_003768; -.
DR eggNOG; KOG0461; Eukaryota.
DR HOGENOM; CLU_019148_1_0_1; -.
DR OMA; LAFWGRI; -.
DR OrthoDB; 54465at2759; -.
DR Proteomes; UP000000673; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR CDD; cd04094; eSelB_III; 1.
DR CDD; cd01889; SelB_euk; 1.
DR CDD; cd03696; SelB_II; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 2.
DR InterPro; IPR049394; eEFSec_C.
DR InterPro; IPR049393; eEFSec_III.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR43721; ELONGATION FACTOR TU-RELATED; 1.
DR PANTHER; PTHR43721:SF11; SELENOCYSTEINE-SPECIFIC ELONGATION FACTOR; 1.
DR Pfam; PF21131; eEFSec_4th; 1.
DR Pfam; PF21208; euk_SelB_III; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Elongation factor {ECO:0000313|EMBL:ETN67204.1};
KW Protein biosynthesis {ECO:0000313|EMBL:ETN67204.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000673}.
FT DOMAIN 2..192
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT COILED 128..155
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 525 AA; 58426 MW; BE420273CA47EBAF CRC64;
MFLNLNVGIL GHVDSGKTTL AKALSAIAST AAFDKHPQSQ ERGITLDLGF SAAQFELPEH
LKGLVGYDRL QFTFVDCPGH ASLIRTIIGG AQIIDMMLLV IDAEKGIQPQ TAECLIIGEL
TCRKMIVVLN KLDTLADAER RAKRLEKLTK GIRETLSKMA FDETPIVAIS ALSGENIQTL
TETMLRRAFL PTRNADLPLM FAVDHCFAIK GQGTVCTGTV LQGTVSVGDK VEIPKLKLER
KVRSIQMFRQ SYTTIRQGDR AGICITQFDP KSLERGIVCA ADYAHYVYAA ILKITPLRYY
KRPIRSKAKF HITCGYETVL ATILLFSTDG KEPFSYDRQY EFLEELTDDA IANRTVFALL
EFEKPILATP DALIIGSKLD SDIQHNTDCR IAFHGHLRLT MREPNYAESV LPGLQVFKQK
CKTGTIQRIV NEQELIVAGL FKKAGSNRQV FLGLTVTLSS GDRGVIEDTF GTGGKVKLRF
HQPIAAEVLE RLNPKTSAKR DDLLVELKFK KFLFERAGKE KKIVQ
//
