ID W5K412_ASTMX Unreviewed; 448 AA.
AC W5K412;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Integrin, beta-like 1 {ECO:0000313|Ensembl:ENSAMXP00000002323.2};
OS Astyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Characidae; Astyanax.
OX NCBI_TaxID=7994 {ECO:0000313|Ensembl:ENSAMXP00000002323.2, ECO:0000313|Proteomes:UP000018467};
RN [1] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RA Jeffery W., Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RX PubMed=25329095; DOI=10.1038/ncomms6307;
RA McGaugh S.E., Gross J.B., Aken B., Blin M., Borowsky R., Chalopin D.,
RA Hinaux H., Jeffery W.R., Keene A., Ma L., Minx P., Murphy D., O'Quin K.E.,
RA Retaux S., Rohner N., Searle S.M., Stahl B.A., Tabin C., Volff J.N.,
RA Yoshizawa M., Warren W.C.;
RT "The cavefish genome reveals candidate genes for eye loss.";
RL Nat. Commun. 5:5307-5307(2014).
RN [3] {ECO:0000313|Ensembl:ENSAMXP00000002323.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; W5K412; -.
DR STRING; 7994.ENSAMXP00000002323; -.
DR Ensembl; ENSAMXT00000002323.2; ENSAMXP00000002323.2; ENSAMXG00000002270.2.
DR eggNOG; KOG1226; Eukaryota.
DR GeneTree; ENSGT01100000263555; -.
DR HOGENOM; CLU_043045_0_0_1; -.
DR InParanoid; W5K412; -.
DR Proteomes; UP000018467; Unassembled WGS sequence.
DR Bgee; ENSAMXG00000002270; Expressed in bone element and 10 other cell types or tissues.
DR Gene3D; 2.10.25.10; Laminin; 9.
DR InterPro; IPR013111; EGF_extracell.
DR InterPro; IPR015812; Integrin_bsu.
DR PANTHER; PTHR10082; INTEGRIN BETA SUBUNIT; 1.
DR PANTHER; PTHR10082:SF60; INTEGRIN BETA-PS; 1.
DR Pfam; PF07974; EGF_2; 5.
DR SUPFAM; SSF57196; EGF/Laminin; 7.
DR PROSITE; PS00243; INTEGRIN_BETA; 5.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000018467};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..448
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5017322974"
FT DOMAIN 48..82
FT /note="EGF-like"
FT /evidence="ECO:0000259|Pfam:PF07974"
FT DOMAIN 89..119
FT /note="EGF-like"
FT /evidence="ECO:0000259|Pfam:PF07974"
FT DOMAIN 183..209
FT /note="EGF-like"
FT /evidence="ECO:0000259|Pfam:PF07974"
FT DOMAIN 278..303
FT /note="EGF-like"
FT /evidence="ECO:0000259|Pfam:PF07974"
FT DOMAIN 410..440
FT /note="EGF-like"
FT /evidence="ECO:0000259|Pfam:PF07974"
SQ SEQUENCE 448 AA; 48562 MW; 02618348969BA465 CRC64;
MNAEALVNSV LVSLLLILLS AVEESLLQSL RQVGGVCKLS TESSQRRCQT SDGLICSGRG
ECECGVCICQ VTDPGKYYGP RCECHDWVCT TYDGKTCGGH GVCDCGKCEC DKGWFGEACQ
YQQNCKLSSR KSKDLCRNAQ GVVCSNAGTC HCGSCMCHNP DGKGLISGRH CECDDSQCLD
EDSGEVCGGH GKCYCGNCYC SAGWHGDKCE FQCDISPWES KRRCTSPDGK ICSNRGTCVC
GECTCYDVDP SGDWGDIHGD TCECDERSCH STYDRYSDDF CSGHGQCNCG RCDCKEGWTG
KKCEHPVSCP LSADASLRKC RGSSKLLPCF GRDHGFCSCG RCICGDGWFG KHCQFPRSCN
MTDEQSKSQC ETANGGMCSG KGSCHCGRCI CSPQEWYISG DFCECDDREC DQHDGLICTG
NGVCNCGTCE CWDGWTGNAC EIWVGEEY
//
