ID W5K790_ASTMX Unreviewed; 329 AA.
AC W5K790;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=NFATC2-interacting protein {ECO:0000256|ARBA:ARBA00039921};
DE AltName: Full=Nuclear factor of activated T-cells, cytoplasmic 2-interacting protein {ECO:0000256|ARBA:ARBA00042764};
OS Astyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Characidae; Astyanax.
OX NCBI_TaxID=7994 {ECO:0000313|Ensembl:ENSAMXP00000003451.2, ECO:0000313|Proteomes:UP000018467};
RN [1] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RA Jeffery W., Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RX PubMed=25329095; DOI=10.1038/ncomms6307;
RA McGaugh S.E., Gross J.B., Aken B., Blin M., Borowsky R., Chalopin D.,
RA Hinaux H., Jeffery W.R., Keene A., Ma L., Minx P., Murphy D., O'Quin K.E.,
RA Retaux S., Rohner N., Searle S.M., Stahl B.A., Tabin C., Volff J.N.,
RA Yoshizawa M., Warren W.C.;
RT "The cavefish genome reveals candidate genes for eye loss.";
RL Nat. Commun. 5:5307-5307(2014).
RN [3] {ECO:0000313|Ensembl:ENSAMXP00000003451.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; W5K790; -.
DR STRING; 7994.ENSAMXP00000003451; -.
DR Ensembl; ENSAMXT00000003451.2; ENSAMXP00000003451.2; ENSAMXG00000003379.2.
DR eggNOG; KOG1769; Eukaryota.
DR GeneTree; ENSGT00390000007119; -.
DR HOGENOM; CLU_067349_0_0_1; -.
DR InParanoid; W5K790; -.
DR Proteomes; UP000018467; Unassembled WGS sequence.
DR Bgee; ENSAMXG00000003379; Expressed in testis and 14 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR InterPro; IPR022617; Rad60/SUMO-like_dom.
DR InterPro; IPR000626; Ubiquitin-like_dom.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR47187; NFATC2-INTERACTING PROTEIN; 1.
DR PANTHER; PTHR47187:SF1; NFATC2-INTERACTING PROTEIN; 1.
DR Pfam; PF11976; Rad60-SLD; 1.
DR SMART; SM00213; UBQ; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000018467}.
FT DOMAIN 174..244
FT /note="Ubiquitin-like"
FT /evidence="ECO:0000259|SMART:SM00213"
FT REGION 40..173
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 57..73
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 97..112
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 152..173
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 329 AA; 36537 MW; 8587A16626F6E23D CRC64;
PNPPAKRRRV IDPSAITSVP IYSNKFQVNS SLQLKPAVFK QVDPTGDEEE ARLWSPSPPK
TKQQPTAITL SDSEDESEQP DTLQSPSPPP PTFSPGRRTR RADKKIEINR RLEVIDSLLC
PSPEREDDDD PGYSDCSSSG NDLDDDDDII IVSNEDKQKR RAPRSEPRGP AREISLKFRW
RTDVHRIPLL STAPLSQAVD QLSAKLKVPP SQILLLKQET ELPTQSTVAE LGLGIADIIC
VVVTEDKEEE NSIRDLITVR LQGKEKGSAQ EYSLHKDDPL GSILTQYTSG LSAAAKRKVK
FLFDGSKVTP NQTPSQLDME NGDVIEVWN
//
