ID W5KBQ3_ASTMX Unreviewed; 785 AA.
AC W5KBQ3;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Kelch domain containing 7A {ECO:0000313|Ensembl:ENSAMXP00000005014.2};
GN Name=KLHDC7A {ECO:0000313|Ensembl:ENSAMXP00000005014.2};
OS Astyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Characidae; Astyanax.
OX NCBI_TaxID=7994 {ECO:0000313|Ensembl:ENSAMXP00000005014.2, ECO:0000313|Proteomes:UP000018467};
RN [1] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RA Jeffery W., Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RX PubMed=25329095; DOI=10.1038/ncomms6307;
RA McGaugh S.E., Gross J.B., Aken B., Blin M., Borowsky R., Chalopin D.,
RA Hinaux H., Jeffery W.R., Keene A., Ma L., Minx P., Murphy D., O'Quin K.E.,
RA Retaux S., Rohner N., Searle S.M., Stahl B.A., Tabin C., Volff J.N.,
RA Yoshizawa M., Warren W.C.;
RT "The cavefish genome reveals candidate genes for eye loss.";
RL Nat. Commun. 5:5307-5307(2014).
RN [3] {ECO:0000313|Ensembl:ENSAMXP00000005014.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; W5KBQ3; -.
DR STRING; 7994.ENSAMXP00000005014; -.
DR Ensembl; ENSAMXT00000005014.2; ENSAMXP00000005014.2; ENSAMXG00000004892.2.
DR eggNOG; KOG1072; Eukaryota.
DR GeneTree; ENSGT00940000162724; -.
DR HOGENOM; CLU_020313_1_0_1; -.
DR InParanoid; W5KBQ3; -.
DR OrthoDB; 5472491at2759; -.
DR Proteomes; UP000018467; Unassembled WGS sequence.
DR Bgee; ENSAMXG00000004892; Expressed in pharyngeal gill and 3 other cell types or tissues.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 1.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR PANTHER; PTHR45972; BTB_2 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45972:SF1; KELCH DOMAIN-CONTAINING PROTEIN 7A; 1.
DR Pfam; PF01344; Kelch_1; 2.
DR SMART; SM00612; Kelch; 2.
DR SUPFAM; SSF117281; Kelch motif; 1.
PE 4: Predicted;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000018467};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REGION 74..94
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 785 AA; 87491 MW; 468889426051F9A8 CRC64;
MPIADLLGVR FDMQLLGKLT LSVAAILLIS WAYRFYSSRA QGQTQTIGRT PLPRGTQTGA
ETCSNCKTVL QPQKKTAKEE ANGESQSRQS SVDLVKDIFK PEESDAAHPC ENEESKSEVF
AFKTMQYSTS VRSDIQDFCQ DAVKETSESK DCKSELTLLL PDEAGKSSTT VNNSSTGRRS
PCLLRKVDGG IEVGRELRQD LGHLGNFSSF QSKAEIKMEN ADLVLEGTGN QNTGVRGKIY
DYYVETSSHS ISDLSPTHSL SPTFGPYETG NLFDSKLSEL SGIMDKPRSP SPLPSALIIR
DLELSHDSDG EPLSPMKSEP IKLLRQGLIR KDSYLAAAVD SELQIPFPPP VTSTPCSHSP
TVPSEMLQNY SDSNNKEMQH INRASFKEPG TQVQTVAGAK FLNFPPQENV GCSELESLKG
KLDLGNCLEA LILAKKYGHS TLQKSALKVM SDNYFQVLRD PALYGRLKAG ERDQIQRQRM
RGRRCLMVAD MESPEWSRLP SQSTMSEAKK ASSGLYYYDD YKDTWHYQCQ IPQEVLSRGC
AMCTMDNYLF VAVGFQGNSL AVPSRKVFCY NPITSIWSEI CPMNEARPHC KLVTLQDHVY
AIGGECLSTV ERYDPRSNRW SFVAPLPNET FAVAHRATAC NGELFVSGGT LKYTLLRYNP
KTDVWRQSLI VGSKERTTEM VAVRNFLYRF DVSPTMGISV YRYHAVARLW YECCSKRMPH
CPAFQCIAMD DVIYCVSRQF TMRFLADEIS PGFVAEDLKV LSAAKGILFP FVLALPDKST
IQTSV
//
