ID W5KWE0_ASTMX Unreviewed; 661 AA.
AC W5KWE0;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 05-DEC-2018, sequence version 2.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=Small ribosomal subunit protein mS39 {ECO:0000256|ARBA:ARBA00035134};
OS Astyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Characidae; Astyanax.
OX NCBI_TaxID=7994 {ECO:0000313|Ensembl:ENSAMXP00000011902.2, ECO:0000313|Proteomes:UP000018467};
RN [1] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RA Jeffery W., Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RX PubMed=25329095; DOI=10.1038/ncomms6307;
RA McGaugh S.E., Gross J.B., Aken B., Blin M., Borowsky R., Chalopin D.,
RA Hinaux H., Jeffery W.R., Keene A., Ma L., Minx P., Murphy D., O'Quin K.E.,
RA Retaux S., Rohner N., Searle S.M., Stahl B.A., Tabin C., Volff J.N.,
RA Yoshizawa M., Warren W.C.;
RT "The cavefish genome reveals candidate genes for eye loss.";
RL Nat. Commun. 5:5307-5307(2014).
RN [3] {ECO:0000313|Ensembl:ENSAMXP00000011902.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
CC -!- SIMILARITY: Belongs to the mitochondrion-specific ribosomal protein
CC mS39 family. {ECO:0000256|ARBA:ARBA00008551}.
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DR AlphaFoldDB; W5KWE0; -.
DR STRING; 7994.ENSAMXP00000011902; -.
DR Ensembl; ENSAMXT00000011902.2; ENSAMXP00000011902.2; ENSAMXG00000011570.2.
DR eggNOG; KOG4422; Eukaryota.
DR GeneTree; ENSGT00390000016876; -.
DR HOGENOM; CLU_026264_0_1_1; -.
DR InParanoid; W5KWE0; -.
DR OrthoDB; 2966953at2759; -.
DR Proteomes; UP000018467; Unassembled WGS sequence.
DR Bgee; ENSAMXG00000011570; Expressed in embryo and 14 other cell types or tissues.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
DR GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR GO; GO:0043024; F:ribosomal small subunit binding; IEA:InterPro.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
DR GO; GO:0032543; P:mitochondrial translation; IEA:InterPro.
DR GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR002885; Pentatricopeptide_rpt.
DR InterPro; IPR037387; PTCD3.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR NCBIfam; TIGR00756; PPR; 2.
DR PANTHER; PTHR16276; PENTATRICOPEPTIDE REPEAT DOMAIN-CONTAINING PROTEIN 3; 1.
DR PANTHER; PTHR16276:SF1; PENTATRICOPEPTIDE REPEAT DOMAIN-CONTAINING PROTEIN 3, MITOCHONDRIAL; 1.
DR Pfam; PF01535; PPR; 1.
DR Pfam; PF13812; PPR_3; 1.
DR PROSITE; PS51375; PPR; 2.
PE 3: Inferred from homology;
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Reference proteome {ECO:0000313|Proteomes:UP000018467};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274};
KW Ribosomal protein {ECO:0000256|ARBA:ARBA00022980};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW rRNA-binding {ECO:0000256|ARBA:ARBA00022730};
KW Translation regulation {ECO:0000256|ARBA:ARBA00022845}.
FT REPEAT 248..282
FT /note="PPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00708"
FT REPEAT 323..357
FT /note="PPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00708"
FT REGION 201..227
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 209..227
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 661 AA; 75338 MW; 0BAF9AB9D5A005AB CRC64;
MASSCVHVGR QIHKTGRIFQ RGARDILQRR YVGLGSAACQ QSAAEVSGSA EEIVIPRKKT
WNKETVLQAL AATVNRDPTA SNYVLQDDSY LIPNSYAQFK LFTLSKESGR NTAKYFINTY
PKYFQKDFAE PHIPCLMPET LELEIEEVSE AALIERIQLR KVKAAVDMYD QLQQSGTPLS
VDLTNDLLDL ICLYGDQDPA PEQGSDYMGE DQEDVKKKEG IPQRDSGISR WRENNNAERI
FHIMPERTRR SYGALIRGMV KYGAYSKAFD MYTDMLNNRL TADVHIFNAL ITAAPEVREQ
IQEKWELVLN LLKQMAKQDV KPNLLTFHAV LRCLRRSRHL AKVFSVFNEM KALGIAPSLA
TYNLILGIVY KQASFAKGHT EILEKVLDEI SGKSFTPQDP DDVKFFINAM RICQEAKDIE
LAYKLHSVVG VGENWKLLGE SYFQNIYYWR FFSLLCMMEN IDVVLKWYKE LIPSLYYPTA
QGMRDFLQAL DTDNRLDLIP QIWKDIKQMG YGNMSDMVEE ILSLMAREKQ SPEVQQAFAD
CALDIKGLYM TQSGPLTWSG ISLRCITSIL LAAERTQQAW EMLNLFKPNN RVPPESLMND
FLASIKASNK AQQAVELVQI SASFCLPVTP SLIERVQQEF ELTEEQRNVL TDLESSADMS
D
//
