ID W5L405_ASTMX Unreviewed; 199 AA.
AC W5L405;
DT 16-APR-2014, integrated into UniProtKB/TrEMBL.
DT 16-APR-2014, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=Transgelin {ECO:0000256|RuleBase:RU361224};
GN Name=TAGLN3 {ECO:0000313|Ensembl:ENSAMXP00000014567.1};
OS Astyanax mexicanus (Blind cave fish) (Astyanax fasciatus mexicanus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes;
OC Characoidei; Characidae; Astyanax.
OX NCBI_TaxID=7994 {ECO:0000313|Ensembl:ENSAMXP00000014567.1, ECO:0000313|Proteomes:UP000018467};
RN [1] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RA Jeffery W., Warren W., Wilson R.K.;
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000018467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=female {ECO:0000313|Proteomes:UP000018467};
RX PubMed=25329095; DOI=10.1038/ncomms6307;
RA McGaugh S.E., Gross J.B., Aken B., Blin M., Borowsky R., Chalopin D.,
RA Hinaux H., Jeffery W.R., Keene A., Ma L., Minx P., Murphy D., O'Quin K.E.,
RA Retaux S., Rohner N., Searle S.M., Stahl B.A., Tabin C., Volff J.N.,
RA Yoshizawa M., Warren W.C.;
RT "The cavefish genome reveals candidate genes for eye loss.";
RL Nat. Commun. 5:5307-5307(2014).
RN [3] {ECO:0000313|Ensembl:ENSAMXP00000014567.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the calponin family.
CC {ECO:0000256|ARBA:ARBA00009631, ECO:0000256|RuleBase:RU361224}.
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DR RefSeq; XP_007249047.1; XM_007248985.2.
DR AlphaFoldDB; W5L405; -.
DR STRING; 7994.ENSAMXP00000014567; -.
DR Ensembl; ENSAMXT00000014567.2; ENSAMXP00000014567.1; ENSAMXG00000014160.2.
DR GeneID; 103030448; -.
DR KEGG; amex:103030448; -.
DR CTD; 797861; -.
DR eggNOG; KOG2046; Eukaryota.
DR GeneTree; ENSGT00940000159385; -.
DR HOGENOM; CLU_055232_1_0_1; -.
DR InParanoid; W5L405; -.
DR OMA; GVMEISC; -.
DR OrthoDB; 11630at2759; -.
DR Proteomes; UP000018467; Unassembled WGS sequence.
DR Bgee; ENSAMXG00000014160; Expressed in bone element and 8 other cell types or tissues.
DR CDD; cd21281; CH_TAGLN3; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR InterPro; IPR000557; Calponin_repeat.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR003096; SM22_calponin.
DR PANTHER; PTHR47385; CALPONIN; 1.
DR PANTHER; PTHR47385:SF10; TRANSGELIN-3; 1.
DR Pfam; PF00402; Calponin; 1.
DR Pfam; PF00307; CH; 1.
DR PRINTS; PR00888; SM22CALPONIN.
DR PRINTS; PR00890; TRANSGELIN.
DR SMART; SM00033; CH; 1.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR PROSITE; PS01052; CALPONIN_1; 1.
DR PROSITE; PS51122; CALPONIN_2; 1.
DR PROSITE; PS50021; CH; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000018467}.
FT DOMAIN 24..136
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
SQ SEQUENCE 199 AA; 22690 MW; 59E82B560073EE27 CRC64;
MANRGPSYGL SREVLEKIEQ KYDTDLEVRL VDWIIAQCGG NLERPLPGKQ NFQNWLMDGT
ILCRLINSLY PRGKEPIKKI QETQMAFKQM EKISQFLVAA EAYGVITTDI FQTVDLWEGK
DMAAVQRTLM ALGSVALTKD DGHYRGNRDW FHRTAQSNRR EFSEEQLRQG QNLIGLQMGS
NRGASQAGMT GYGMHRQIM
//
